KEGG   ORTHOLOGY: K18553
Entry
K18553                      KO                                     
Symbol
cmlR, cmx
Name
MFS transporter, DHA1 family, chloramphenicol resistance protein
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K18553  cmlR, cmx; MFS transporter, DHA1 family, chloramphenicol resistance protein
   01504 Antimicrobial resistance genes
    K18553  cmlR, cmx; MFS transporter, DHA1 family, chloramphenicol resistance protein
Transporters [BR:ko02000]
 Major facilitator superfamily (MFS)
  Drug transporters
   Drug:H+ antiporter-1 (12 spanner) (DHA1) family
    K18553  cmlR, cmx; MFS transporter, DHA1 family, chloramphenicol resistance protein
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Phenicol resistance genes
   Transporters
    K18553  cmlR, cmx; MFS transporter, DHA1 family, chloramphenicol resistance protein
Other DBs
COG: COG2814
TC: 2.A.1.2.32
Genes
CYO: CD187_14370
CPOT: FOB25_02320
KIE: NCTC12125_01727(araJ_2)
SLQ: M495_11285
SFG: AV650_13610
GQU: AWC35_01775
RBAD: H2866_00255
XBO: XBJ1_3303
XBV: XBW1_3659
XDO: XDD1_0403 XDD1_0772
PAE: PA3336
PAEV: N297_3455
PAEI: N296_3455
PAU: PA14_20900
PAG: PLES_17281
PAF: PAM18_1629
PNC: NCGM2_4466
PAEB: NCGM1900_2940
PDK: PADK2_07590
PSG: G655_08080
PRP: M062_17820
PAEP: PA1S_08665
PAER: PA1R_gp1173
PAEM: U769_08165
PAEL: T223_08665
PAES: SCV20265_1712
PAEU: BN889_03705
PAEG: AI22_25220
PAEC: M802_3454
PAEO: M801_3320
SECH: B18_29685
PVD: CFBP1590__2753
PGG: FX982_03884
PKV: QYQ93_00905
CVC: BKX93_14730
CHRO: CXB49_20790
PPK: U875_02905
PPNO: DA70_19975
PPNM: LV28_10410
PRB: X636_06555
PPUL: RO07_04690
PSPU: NA29_00440
PAPI: SG18_05155
PVE: UC34_20775
POX: MB84_00680
PFG: AB870_07605
PNR: AT302_04330
PFIB: PI93_007225
PCOM: NTU39_22905
ACHR: C2U31_23510
AKA: TKWG_21575
AFA: UZ73_11570
PHN: PAEH1_11300
DIH: G7047_09900
JAZ: YQ44_10545
MNR: ACZ75_19195
MASS: CR152_21610
SHIN: LHJ69_23950(cmx)
PLUT: EI981_16660
MYV: G155_06380 G155_09900
MDX: BTO20_06325
MYJ: BCA37_11670
MSM: MSMEG_2028 MSMEG_6245
MSG: MSMEI_1983 MSMEI_6084
MSB: LJ00_10115 LJ00_30880
MSN: LI99_10115 LI99_30885
MSH: LI98_10115 LI98_30890
MNE: D174_19500
MYN: MyAD_19130
MFT: XA26_12730 XA26_20280
MPHL: MPHLCCUG_01471(ydhP)
MTY: MTOK_39170
MMUC: C1S78_008990
MMAT: MMAGJ_49540
MBOK: MBOE_23430 MBOE_54830
MFG: K6L26_22570
MGO: AFA91_28910
MSEN: K3U95_19920
MAB: MAB_2983c
MMV: MYCMA_1645
MABB: MASS_2918
MABL: MMASJCM_2982
CDB: CDBH8_0915(cmx)
CJK: jk1404(cmx)
CUR: cu0744(cmx1) cu1541(cmx2)
CUA: CU7111_1486(cmx)
CGY: CGLY_05495 CGLY_06050
CII: CIMIT_00705
CSX: CSING_01975(cmlR)
CPRP: I6I69_04605(cmx)
CHAD: CHAD_02605(ydhP)
CAFE: CAFEL_01280(ydhP)
CPYR: CYJ47_11095(cmx)
CPSK: Q0N40_08960(cmx)
NFA: NFA_18010 NFA_18410
NFR: ERS450000_02312(ydhP_2)
NCY: NOCYR_1919(cmlR) NOCYR_4769(cmlR)
NBR: O3I_011970 O3I_014290 O3I_021205 O3I_023215 O3I_031350
NNO: NONO_c42230 NONO_c75770
NTP: CRH09_09345 CRH09_36515 CRH09_39220
NOZ: DMB37_04495 DMB37_10255 DMB37_32540 DMB37_35900 DMB37_36925
NOD: FOH10_10245 FOH10_14825 FOH10_17685
NAH: F5544_09085 F5544_15555(cmx_cmrA) F5544_16750 F5544_21805(cmx_cmrA) F5544_22855
NWL: NWFMUON74_18470 NWFMUON74_70980
NIE: KV110_11890 KV110_11975
NYA: LTV02_13920
NGP: LTT66_02200 LTT66_26715
NSPU: IFM12276_09960 IFM12276_44060
NVU: V7968_19760 V7968_22025 V7968_30995 V7968_39175
RQI: C1M55_29560
RHOD: AOT96_09215
RHOP: D8W71_04325
RHOH: CPI83_30335
WHR: OG579_09640
TSM: ASU32_00400 ASU32_09380 ASU32_21775
SCO: SCO7526(cmlR1) SCO7662(SC10F4.35)
SALB: XNR_2375
SGR: SGR_2986 SGR_3196
SGB: WQO_19755 WQO_20760
SFI: SFUL_4133 SFUL_4366
SANL: KZO11_20725 KZO11_21980
SGRF: SGFS_055440
SCYE: R2B67_14015 R2B67_15390
SCB: SCAB_50641(cmlR1)
SSX: SACTE_1684 SACTE_3734
SVL: Strvi_7788 Strvi_8749
SRC: M271_27900 M271_32735
SMAL: SMALA_2521 SMALA_3455
SSOI: I1A49_16050 I1A49_21040
SFA: Sfla_2770 Sfla_4582
SBH: SBI_04941 SBI_07037
SVE: SVEN_0916 SVEN_4065
STRP: F750_2108 F750_4027
SLV: SLIV_01010(cmlR) SLIV_01680
SGU: SGLAU_19650
SVT: SVTN_21065 SVTN_38950
STRE: GZL_02005 GZL_03657 GZL_04030
SCW: TU94_23355
SLD: T261_2576 T261_3028 T261_3402
SLC: SL103_23715 SL103_32200
SXI: SXIM_14520 SXIM_32040
STRM: M444_16155
STRC: AA958_07920 AA958_15100 AA958_19820
SAMB: SAM23877_0687(cmlR) SAM23877_5283(cmlR)
SPRI: SPRI_4128 SPRI_6811
SCZ: ABE83_14430 ABE83_15630
SRW: TUE45_00792(ydhP_1)
STRF: ASR50_33230
SLE: sle_21230(sle_21230)
SRN: A4G23_02392(ydhP)
SPAV: Spa2297_01125 Spa2297_26840
SCLF: BB341_12200 BB341_27065
SGS: AVL59_22775
SKY: D0C37_13720
SALW: CP975_15735 CP975_28200
SGM: GCM10017557_37570
SPHW: NFX46_37090
SLS: SLINC_1106 SLINC_5971
SNR: SNOUR_08970 SNOUR_16260 SNOUR_17970
SALU: DC74_4795 DC74_5185 DC74_6761
SALL: SAZ_25670 SAZ_27565 SAZ_35110
STRD: NI25_20850 NI25_35825
SNW: BBN63_19065 BBN63_33370
SAUO: BV401_16120 BV401_20740
SSIA: A7J05_19735 A7J05_29775
SVU: B1H20_20970
SPUN: BFF78_28840
SGV: B1H19_24560
SLAU: SLA_0056 SLA_4145
SALF: SMD44_03841 SMD44_06856 SMD44_06973
SALJ: SMD11_6318
SLX: SLAV_17420(ydhP2)
STRO: STRMOE7_23160
SFK: KY5_1233 KY5_3654 KY5_6223
SRJ: SRO_0146
SGD: ELQ87_34875
SQZ: FQU76_14025
SAST: CD934_00995
SNQ: CP978_15580
STIR: DDW44_13685 DDW44_15190
SKA: CP970_09925 CP970_24020 CP970_36625
SGZ: C0216_28730
SVN: CP980_18785
SNK: CP967_14805 CP967_24825
SHAW: CEB94_28940
SFIC: EIZ62_18165
SSPO: DDQ41_13790
SPAD: DVK44_19345
SFY: GFH48_22615(cmx_cmrA)
SAQU: EJC51_33895
SGF: HEP81_00125
SCAV: CVT27_18915 CVT27_20150
SSEO: D0Z67_26825
SBY: H7H31_10945 H7H31_20040 H7H31_20595
SRIM: CP984_14255 CP984_16060
SSUB: CP968_18760
SPHV: F9278_21300
SCIN: CP977_19370
SFUG: CNQ36_01030
SPAC: B1H29_10965 B1H29_35070
STSU: B7R87_13530
SCHA: CP983_12975
SGX: H4W23_22510
SCOE: CP976_00420 CP976_00450 CP976_03270 CP976_30530 CP976_35790
SBAT: G4Z16_19260
SSPB: CP982_32570 CP982_32885
SNF: JYK04_03983(ydhP_2)
SPLA: CP981_23205 CP981_32330
SBRO: GQF42_00720(cmx_cmrA) GQF42_02090(cmx_cmrA)
SATA: C5746_23070 C5746_33875
SHUN: DWB77_03550(ydhP_1) DWB77_07150(ydhP_3)
SHAR: HUT13_07970 HUT13_16545
SFEU: IM697_35560
SLIA: HA039_19430
SDW: K7C20_22075 K7C20_23820 K7C20_30890
SVD: CP969_32895
SCAL: I6J39_14695 I6J39_20795
SAUH: SU9_020195
SFB: CP974_13105
SMOB: J7W19_01055
SPEU: CGZ69_16095
SROI: IAG44_26250
SXN: IAG42_20850
SGJ: IAG43_13790 IAG43_25025
SHK: J2N69_05315 J2N69_16520 J2N69_29395
SANU: K7396_06320 K7396_14830
STRY: EQG64_19655
SDD: D9753_34730
SACT: DMT42_37305
SMAO: CAG99_11875 CAG99_15635
SINE: KI385_27145 KI385_28905 KI385_36635
SLF: JEQ17_14780 JEQ17_21080
SDEC: L3078_20470
SAOV: G3H79_06205 G3H79_06540 G3H79_20375
SDUR: M4V62_11210 M4V62_23605 M4V62_28715
SYAN: NRK68_15195
SRUG: F0345_09290(cmx_cmrA) F0345_16500(cmx_cmrA)
SAKB: K1J60_24325
STAA: LDH80_06735 LDH80_18245
SNIG: HEK616_45840 HEK616_63500
SVIO: HWN34_12515
SCAE: IHE65_24825
STUB: MMF93_14885 MMF93_32170
SXT: KPP03845_104238(ydhP_1)
SLON: LGI35_21365 LGI35_42675
STUD: STRTU_001043 STRTU_002824
STEE: F3L20_22515
SENG: OJ254_05855 OJ254_27505
SGK: PET44_14875
SANT: QR300_24225 QR300_28815
SYUN: MOV08_08860 MOV08_16175 MOV08_18010
SARG: HKX69_33925
SJN: RI060_03170 RI060_11880
SOV: QZH56_34725
SFIY: F0344_14440(cmx_cmrA) F0344_15180(cmx_cmrA) F0344_34465
SHAU: K9S39_18700
SKG: KJK29_09965
SCOA: QU709_11655
SLAI: P8A22_06105 P8A22_17275
SROC: RGF97_14300
SFP: QUY26_07175 QUY26_07575 QUY26_21940
SCHG: NRO40_13205 NRO40_23070
STTN: BSL84_14905
STRZ: OYE22_10570 OYE22_19560 OYE22_20045
KBU: Q4V64_37390
SARM: DVA86_12095 DVA86_25545
SPRF: K4G22_17145 K4G22_29065
SLUO: PS467_18945
STPB: QR97_36365
SRPA: HEP86_24330 HEP86_33640
SMIB: SMIR_20695
SCAJ: O1G22_38550
STRL: HEP84_24135
STSD: HEP87_25100
SRPZ: HEP85_18610
SCHE: QRN89_15775
SGLY: P8A20_15755 P8A20_26510
SCAT: P8A18_18945
STII: DRB96_33415
STRV: EZV63_01640 EZV63_18075
SPAZ: ABXI76_14605 ABXI76_15850
SPIH: ABXR15_18255
SMOD: POD33_21035
SPOF: P8A21_22200 P8A21_33150
SCT: SCAT_5431(cmlR)
SCY: SCATT_54300 SCATT_p04570
KSK: KSE_11240
KAB: B7C62_19880 B7C62_21300
STRI: C7M71_022680
YIA: LO772_34880
LXL: KDY119_03161
MIP: AXH82_01020
MOY: CVS54_02664(ydhP_2)
MRN: K8F61_12530
MLIQ: NMQ05_00755 NMQ05_12950(cmx)
MPAO: IZR02_11680 IZR02_17285
MSUW: GCM10025863_02120
MSUF: KV394_16875
MICI: AB2L57_07830
AGY: ATC03_19070
ASOI: MTP13_00725
PLAP: EAO79_08845
LARI: KI794_14530(cmx) KI794_14620(cmx)
GMN: GMOLON4_815(araJ)
ARM: ART_2183
ARN: CGK93_02580
ARI: UM93_12510
PUE: FV140_01960(cmx) FV140_02135(cmx) FV140_04290(cmx) FV140_08375(cmx) FV140_09330(cmx) FV140_12070(cmx) FV140_12590(cmx) FV140_14525(cmx) FV140_15300(cmx) FV140_16935(cmx) FV140_17870(cmx) FV140_18590(cmx) FV140_19470(cmx) FV140_19910(cmx) FV140_19955(cmx)
GAR: AOZ07_05575
GCR: GcLGCM259_2952
GLU: F0M17_17030(cmx)
GPR: JQN66_18025(cmx) JQN66_18335(cmx)
MICU: SOY78_00130(cmx)
NAE: BHE16_08480 BHE16_08520
PAEY: KUF55_05525
BFA: Bfae_04270
BRV: CFK39_15595
BSAU: DWV08_16135
DVA: DAD186_04200
DJJ: COP05_07600 COP05_07765
KSE: Ksed_23780
LMOI: VV02_03630
BEI: GCM100_09320
IDO: I598_0491(ydhP_2)
CELE: P9841_01875
BLY: A2T55_00825
BLIN: BLSMQ_0018
BLUT: EW640_02945
BCAU: I6G59_03950 I6G59_06755
BSPO: L1F31_01970
BREB: PGC08_00115
RHAL: LQF10_17095
PRV: G7070_06005
PROP: QQ658_12065
NOO: FE634_00695
NOCW: ABFU82_12600
NOCL: KM427_00180 KM427_01125
NOCD: QJ852_10570
NOCQ: QI633_27115(cmx)
AEZ: C3E78_01635
MUZ: H4N58_08800
SGRG: L0C25_10630
KFL: Kfla_0416 Kfla_1115 Kfla_1235 Kfla_3507
KQI: F1D05_04400
KSL: OG809_31520 OG809_32095
KRI: OX958_18435
NAL: B005_2967
NFE: HUT17_01265
NCG: KGD84_01115
SAIU: J4H86_12850
ACTW: F7P10_10355 F7P10_30885
AGRA: AGRA3207_000524 AGRA3207_005836
AMAZ: LUW76_08100 LUW76_15920
ACIR: OG979_09975 OG979_26320 OG979_33090
SPIQ: OHA34_16000 OHA34_26185 OHA34_30370
ACTQ: OG417_08855 OG417_18315
SRO: Sros_5394 Sros_7927
NOA: BKM31_01460 BKM31_50660
NOW: GBF35_23335 GBF35_36535(cmx_cmrA) GBF35_45435(cmx_cmrA)
NCX: Nocox_28300(ydhP1) Nocox_29660(ydhP2)
NGN: LCN96_40830 LCN96_50715
NFS: OIE67_08205 OIE67_53735
MHAI: OHB01_32875
MMAR: MODMU_2443
SACC: EYD13_06845(ydhP2) EYD13_15575(ydhP4)
AMD: AMED_4939(araJ)
AMN: RAM_25145
AMM: AMES_4880(araJ)
AMZ: B737_4880(araJ)
AOI: AORI_3783(araJ) AORI_4153 AORI_7084
AJA: AJAP_03680 AJAP_18165(cmlR) AJAP_20245
AMYC: CU254_13730 CU254_18085 CU254_40875
AMYB: BKN51_11385 BKN51_13690 BKN51_28680
AAB: A4R43_01600 A4R43_11025 A4R43_15435
AMYY: YIM_15015(ydhP1) YIM_25195(ydhP2) YIM_27535(ydhP4) YIM_33145(ydhP5) YIM_41500(ydhP7)
AORI: SD37_19405 SD37_21275 SD37_23005
APRT: MUY14_12935 MUY14_29610
AROO: NQK81_00035 NQK81_03670 NQK81_30395
ATHM: L1857_00370 L1857_11315
ARHD: VSH64_13420
AMOG: QRX60_04180 QRX60_38695
ACYN: ORV05_18260
ACOR: LCL61_12130 LCL61_23690 LCL61_25855
AMYZ: HUW46_02931(ydhP_2) HUW46_04642(ydhP_3) HUW46_08935(ydhP_4)
ACAB: QRX50_32255 QRX50_41055
ANW: QP939_39255
AMYD: K1T34_35380 K1T34_45460
AMYE: MJQ72_07355 MJQ72_09405
AMYS: CVV72_07425 CVV72_09560 CVV72_34320
PSEE: FRP1_05500
PSEQ: AD006_13130
PECQ: AD017_20965
PHH: AFB00_03235 AFB00_12170 AFB00_25240
PAUT: Pdca_04460
PSDS: K1T35_01870 K1T35_38020
APRE: CNX65_15570
SACX: IOD16_10945
KAL: KALB_2640
KUT: JJ691_50460
KPHY: AOZ06_17480 AOZ06_37825 AOZ06_48755
AHM: TL08_13390
ACTI: UA75_15915
ACAD: UA74_15355
AHG: AHOG_14300(ydhP3)
PMAD: BAY61_15560
ACTU: Actkin_02356(ydhP_1) Actkin_02953(ydhP_2)
CROS: N8J89_21645
UME: RM788_46015
MICH: FJK98_12010
MCAB: HXZ27_17740
MSAG: GCM10017556_14690
VMA: VAB18032_15975
MCHL: PVK74_02960
MCAY: PVK37_18245
PFLA: Pflav_046220
ATL: Athai_45720 Athai_65670
ASER: Asera_09560 Asera_29310
PRY: Prubr_72970
DFU: Dfulv_20155
DACT: KZZ52_34615
SNA: Snas_0384 Snas_5751
GLY: K3N28_13930
STUC: G5S47_08010(cmx)
BCHO: BcFMB_09240
BSUE: BS3272_04540
KBS: EPA93_13100
AG: AAB36568(cmlv) AAC63090(cmx) CAA42594(cml) CAA78046(cmr)
 » show all
Reference
PMID:1779766
  Authors
Dittrich W, Betzler M, Schrempf H
  Title
An amplifiable and deletable chloramphenicol-resistance determinant of Streptomyces lividans 1326 encodes a putative transmembrane protein.
  Journal
Mol Microbiol 5:2789-97 (1991)
DOI:10.1111/j.1365-2958.1991.tb01987.x
Reference
PMID:7592948
  Authors
Mosher RH, Camp DJ, Yang K, Brown MP, Shaw WV, Vining LC
  Title
Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer.
  Journal
J Biol Chem 270:27000-6 (1995)
DOI:10.1074/jbc.270.45.27000
  Sequence
[sve:SVEN_4065]
Reference
PMID:1406276
  Authors
Desomer J, Vereecke D, Crespi M, Van Montagu M
  Title
The plasmid-encoded chloramphenicol-resistance protein of Rhodococcus fascians is homologous to the transmembrane tetracycline efflux proteins.
  Journal
Mol Microbiol 6:2377-85 (1992)
DOI:10.1111/j.1365-2958.1992.tb01412.x
Reference
PMID:23162539
  Authors
Roberts MC, Schwarz S, Aarts HJ
  Title
Erratum: Acquired antibiotic resistance genes: an overview.
  Journal
Front Microbiol 3:384 (2012)
DOI:10.3389/fmicb.2012.00384
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