KEGG   ORTHOLOGY: K19349
Entry
K19349            Tight     KO                                     
Symbol
vga
Name
pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
Pathway
map02010  ABC transporters
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K19349  vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K19349  vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
   01504 Antimicrobial resistance genes
    K19349  vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  Other subfamilies
   Macrolide exporter
    K19349  vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Macrolide resistance genes
   Transporters
    K19349  vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein
Other DBs
COG: COG0488
TC: 3.A.1.121.2 3.A.1.121.5
Genes
BCY: Bcer98_1435
BMYC: DJ92_4373
BPU: BPUM_3091
BPUM: BW16_16595
BPUS: UP12_16095
BSM: BSM4216_1907
BALT: CFN77_16515(abc-f)
BACW: QR42_15575
BACO: OXB_2215
BCO: Bcell_0499
BCOH: BC6307_05400
BKO: CKF48_08315
BDA: FSZ17_02050(vga)
OIH: OB0449
OCN: CUC15_02075
GTN: GTNG_1567
GJF: M493_08855
ANM: GFC28_750
ANL: GFC29_876
AND: GRQ40_09135(vga)
AXL: AXY_06210
VIG: BKP57_13715
VPN: A21D_00774(uup_1)
APAK: AP3564_14225
GRC: GI584_02505(abc-f)
SALE: EPH95_16425(abc-f)
BLEN: NCTC4824_00261(yjjK_1)
STEA: C0679_01450(vga)
SAUB: C248_1698
SCA: SCA_0057(vba)
SMUS: C7J88_07350
SPIC: SAMEA4384060_2470(vba)
SHV: AAT16_09620
JEA: JEM45_10790(abc-f)
SBAC: BVH56_02095
PMS: KNP414_05542
PMQ: PM3016_4912
PMW: B2K_25445
PLUT: EI981_24870(vga)
TCO: Theco_0522
ANX: ACH33_09255
COH: EAV92_06945
JEO: JMA_06890
KZO: NCTC404_02029
RST: ATY39_01285
PAEK: D3873_01440(abc-f)
VIJ: JNUCC6_06945(abc-f)
TVU: AB849_003565(abc-f)
LPD: AYR62_09875
VTE: BHY08_04770
ABAE: CL176_07925
JPO: G7058_11810(vga)
DPM: FNV33_04675
AG: AAB95639(vga(B)) ACX92986(vga(D)) CAY33094(vga(C)) CBL58193(vga(A)) CBY88983(vga(E))
 » show all
Reference
PMID:18838584
  Authors
Gentry DR, McCloskey L, Gwynn MN, Rittenhouse SF, Scangarella N, Shawar R, Holmes DJ
  Title
Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus.
  Journal
Antimicrob Agents Chemother 52:4507-9 (2008)
DOI:10.1128/AAC.00915-08
  Sequence
[ag:CBL58193]
Reference
PMID:18562322
  Authors
Jacquet E, Girard JM, Ramaen O, Pamlard O, Levaique H, Betton JM, Dassa E, Chesneau O
  Title
ATP hydrolysis and pristinamycin IIA inhibition of the Staphylococcus aureus Vga(A), a dual ABC protein involved in streptogramin A resistance.
  Journal
J Biol Chem 283:25332-9 (2008)
DOI:10.1074/jbc.M800418200
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