KEGG   ORTHOLOGY: K19437
Entry
K19437                      KO                                     
Symbol
RL1
Name
HSV1 neurovirulence factor ICP34.5
Pathway
map05168  Herpes simplex virus 1 infection
Network
nt06133  RLR signaling (viruses)
nt06138  PKR-eIF2alpha signaling (viruses)
nt06168  Herpes simplex virus 1 (HSV-1)
  Element
N00567  HSV ICP34.5 to TBK1 signaling pathway
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K19437  RL1; HSV1 neurovirulence factor ICP34.5
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19437  RL1; HSV1 neurovirulence factor ICP34.5
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human herpes simplex virus
   K19437  RL1; HSV1 neurovirulence factor ICP34.5
Genes
VG: 1487286(RL1) 1487287(RL1) 18533951(RL1) 18533967(RL1) 19621650(RL1) 19621718(RL1) 2703395(RL1) 2703396(RL1)
Reference
PMID:8077935
  Authors
Brown SM, Harland J, MacLean AR, Podlech J, Clements JB
  Title
Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2.
  Journal
J Gen Virol 75 ( Pt 9):2367-77 (1994)
DOI:10.1099/0022-1317-75-9-2367
  Sequence
[vg:2703395]
Reference
  Authors
Manivanh R, Mehrbach J, Knipe DM, Leib DA
  Title
Role of Herpes Simplex Virus 1 gamma34.5 in the Regulation of IRF3 Signaling.
  Journal
J Virol 91:e01156-17 (2017)
DOI:10.1128/JVI.01156-17
  Sequence
[vg:2703396]
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