KEGG   NETWORK: N00567
Entry
N00567                      Network                                
Name
HSV ICP34.5 to TBK1 signaling pathway
Definition
ICP34.5 -| (TBK1+IKBKE)
  Expanded
K19437 -| (29110+9641)
Class
nt06519 RLR signaling
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
29110  TBK1; TANK binding kinase 1
9641  IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
Perturbant
K19437 (ICP34.5)  RL1; HSV1 neurovirulence factor ICP34.5
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
Ma Y, Jin H, Valyi-Nagy T, Cao Y, Yan Z, He B
  Title
Inhibition of TANK binding kinase 1 by herpes simplex virus 1 facilitates productive infection.
  Journal
J Virol 86:2188-96 (2012)
DOI:10.1128/JVI.05376-11
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