KEGG   ORTHOLOGY: K19439
Entry
K19439                      KO                                     
Symbol
US3
Name
Simplexvirus serine/threonine-protein kinase US3 [EC:2.7.11.1]
Pathway
map05168  Herpes simplex virus 1 infection
Network
nt06168  Herpes simplex virus 1 (HSV-1)
nt06517  TLR signaling
nt06519  RLR signaling
nt06522  mTOR signaling
nt06524  Apoptosis
  Element
N00562  HSV US3 to TLR2/4-NFKB signaling pathway
N00564  HSV US3 to TLR3-NFKB signaling pathway
N00568  HSV US3 to IRF3 signaling pathway
N00584  HSV US3 to MTOR signaling pathway
N00585  HSV US3 to intrinsic apoptotic pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K19439  US3; Simplexvirus serine/threonine-protein kinase US3
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K19439  US3; Simplexvirus serine/threonine-protein kinase US3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K19439  US3; Simplexvirus serine/threonine-protein kinase US3
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human herpes simplex virus 1/2
   K19439  US3; Simplexvirus serine/threonine-protein kinase US3
Genes
VG: 1487355(US3) 1487456(US3) 18533955(US3) 19621710(US3) 26828095(US3) 26887585(US3) 2703401(US3) 3190350(US3) 32707837(US3) 3850193(US3) 9829362(US3)
Reference
PMID:1656069
  Authors
Purves FC, Spector D, Roizman B
  Title
The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates posttranslational modification of the phosphoprotein encoded by the UL34 gene.
  Journal
J Virol 65:5757-64 (1991)
DOI:10.1128/JVI.65.11.5757-5764.1991
  Sequence
[vg:2703401]
Reference
PMID:29896662
  Authors
Kato A, Kawaguchi Y
  Title
Us3 Protein Kinase Encoded by HSV: The Precise Function and Mechanism on Viral Life Cycle.
  Journal
Adv Exp Med Biol 1045:45-62 (2018)
DOI:10.1007/978-981-10-7230-7_3
  Sequence
[vg:2703401]
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