KEGG   NETWORK: N00568
Entry
N00568                      Network                                

Name
HSV US3 to IRF3 signaling pathway
Definition
US3 -| IRF3
  Expanded
K19439 -| 3661
Class
nt06133 RLR signaling (viruses)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
3661  IRF3; interferon regulatory factor 3
Perturbant
K19439 (US3)  US3; Simplexvirus serine/threonine-protein kinase US3
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
Wang S, Wang K, Lin R, Zheng C
  Title
Herpes simplex virus 1 serine/threonine kinase US3 hyperphosphorylates IRF3 and inhibits beta interferon production.
  Journal
J Virol 87:12814-27 (2013)
DOI:10.1128/JVI.02355-13
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