KEGG   ORTHOLOGY: K19722
Entry
K19722                      KO                                     
Symbol
AGER, RAGE
Name
receptor for advanced glycosylation end products
Pathway
map04148  Efferocytosis
map04613  Neutrophil extracellular trap formation
map04933  AGE-RAGE signaling pathway in diabetic complications
map05010  Alzheimer disease
map05022  Pathways of neurodegeneration - multiple diseases
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
   05022 Pathways of neurodegeneration - multiple diseases
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
   05415 Diabetic cardiomyopathy
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K19722  AGER, RAGE; receptor for advanced glycosylation end products
Other DBs
GO: 0050785
Genes
HSA: 177(AGER)
PTR: 462584(AGER)
PPS: 100988780(AGER)
GGO: 101150956(AGER)
PON: 100443859(AGER)
PPYG: 129039447(AGER)
NLE: 101178250(AGER)
HMH: 116460305(AGER)
SSYN: 129473801(AGER)
MCC: 717296(AGER)
MCF: 102121124(AGER)
MTHB: 126953221
MNI: 105497586(AGER)
CSAB: 103221709(AGER)
CATY: 105574096(AGER)
TGE: 112623219(AGER)
MLEU: 105531507(AGER)
RRO: 104673948(AGER)
RBB: 108519888(AGER) 108524385
TFN: 117086989(AGER)
PTEH: 111528961(AGER)
CANG: 105513780(AGER)
CJC: 100414002(AGER)
SBQ: 101043104(AGER)
CIMI: 108300106(AGER)
ANAN: 105706390(AGER)
CSYR: 103271313(AGER)
MMUR: 105858148(AGER)
LCAT: 123631780(AGER)
PCOQ: 105817852(AGER)
OGA: 100955543(AGER)
MMU: 11596(Ager)
MCAL: 110312645(Ager)
MPAH: 110335608(Ager)
RNO: 81722(Ager)
MCOC: 116075328(Ager)
ANU: 117724835(Ager)
ASYL: 127670073(Ager)
MUN: 110565392(Ager)
CGE: 100757624(Ager)
MAUA: 101842404(Ager)
PROB: 127224299(Ager)
PLEU: 114705813(Ager)
MORG: 121435265(Ager)
MFOT: 126495194
AAMP: 119822474(Ager)
NGI: 103724405(Ager)
HGL: 101709133(Ager)
CPOC: 100726130(Ager)
CCAN: 109690410(Ager)
DORD: 105999851(Ager)
DSP: 122111560(Ager)
PLOP: 125352737(Ager)
NCAR: 124988641
MMMA: 107143760(Ager)
ITI: 101972046(Ager)
OCU: 100343142 127493058
OPI: 101535661(AGER)
TUP: 102486051(AGER)
GVR: 103583660 103603632(AGER)
CFA: 403168(AGER)
CLUD: 112641348(AGER)
VVP: 112913637(AGER)
VLG: 121475913(AGER)
NPO: 129512915(AGER)
AML: 100477105(AGER)
UMR: 103682274(AGER)
UAH: 113243764(AGER)
UAR: 123790961(AGER)
ELK: 111152179
LLV: 125102493
MPUF: 101682399(AGER)
MNP: 132017838(AGER)
MLK: 131834310(AGER)
ORO: 101383547(AGER)
EJU: 114222252(AGER)
ZCA: 113926528(AGER)
MLX: 118027195(AGER)
NSU: 110586748(AGER)
LWW: 102737983(AGER)
FCA: 101096892(AGER)
PYU: 121022315(AGER)
PCOO: 112853779(AGER)
PBG: 122478243(AGER)
PVIV: 125165844(AGER)
LRUF: 124529037
LGF: 123608183(AGER)
AJU: 106983491
PTG: 102963427(AGER)
PPAD: 109260522(AGER)
PUC: 125938409
PLEZ: 122219734(AGER)
HHV: 120221861(AGER)
BTA: 280986(AGER)
BOM: 102266016(AGER)
BIU: 109577209(AGER)
BBUB: 102399460(AGER)
BBIS: 104983965(AGER)
CHX: 102168873(AGER)
OAS: 101111586(AGER)
BTAX: 128056470(AGER)
CSUM: 138069228(AGER)
ODA: 120870594(AGER)
CCAD: 122429906(AGER)
MREE: 136151743(AGER)
OVR: 110147765(AGER)
MBEZ: 129543130(AGER)
SSC: 396591(AGER)
CFR: 102523226(AGER)
CBAI: 105074023(AGER)
CDK: 105090848(AGER)
VPC: 102531985(AGER)
BACU: 103013422(AGER)
BMUS: 118904553(AGER)
LVE: 103089458(AGER)
OOR: 101275831(AGER)
LALB: 132527447(AGER)
DLE: 111170949(AGER)
PCAD: 102976074(AGER)
PSIU: 116762482(AGER)
PPHC: 136128808(AGER)
NASI: 112395381(AGER)
ECB: 100051699(AGER)
EPZ: 103566647(AGER)
EAI: 106831014(AGER)
MYB: 102258384(AGER)
MYD: 102752127(AGER)
MMYO: 118679606(AGER)
MLF: 102432909(AGER)
MDT: 132237699(AGER)
MYUM: 139012666(AGER)
PKL: 118705124(AGER)
EFUS: 103300446(AGER)
MNA: 107538992(AGER)
DRO: 112302184(AGER)
SHON: 118991461(AGER)
AJM: 119053725(AGER)
PDIC: 114495630(AGER)
PHAS: 123810501(AGER)
MMF: 118621128(AGER)
PPAM: 129067344(AGER)
HAI: 109373121(AGER)
RFQ: 117020521(AGER)
PALE: 102896393(AGER)
PGIG: 120618880(AGER)
PVP: 105305278(AGER)
RAY: 107498452(AGER)
MJV: 108393802(AGER)
TOD: 119252247(AGER)
SARA: 101545016(AGER)
SFUM: 130035671(AGER)
SETR: 125995716(AGER)
LAV: 100661497(AGER)
TMU: 101354153
ETF: 101646399(AGER)
DNM: 101438376(AGER)
MDO: 100024116(AGER)
GAS: 123243879(AGER)
SHR: 100933743(AGER)
AFZ: 127561102
PCW: 110199342(AGER)
TVP: 118856185(AGER)
PBRV: 138150017(AGER)
OAA: 100090019(AGER)
TACU: 119946761(AGER)
LCM: 102360629(AGER)
 » show all
Reference
PMID:1378843
  Authors
Neeper M, Schmidt AM, Brett J, Yan SD, Wang F, Pan YC, Elliston K, Stern D, Shaw A
  Title
Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.
  Journal
J Biol Chem 267:14998-5004 (1992)
  Sequence
[hsa:177]
Reference
PMID:18089847
  Authors
Hudson BI, Carter AM, Harja E, Kalea AZ, Arriero M, Yang H, Grant PJ, Schmidt AM
  Title
Identification, classification, and expression of RAGE gene splice variants.
  Journal
FASEB J 22:1572-80 (2008)
DOI:10.1096/fj.07-9909com
Reference
PMID:19906677
  Authors
Fang F, Lue LF, Yan S, Xu H, Luddy JS, Chen D, Walker DG, Stern DM, Yan S, Schmidt AM, Chen JX, Yan SS
  Title
RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.
  Journal
FASEB J 24:1043-55 (2010)
DOI:10.1096/fj.09-139634
  Sequence
[hsa:177]
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