Homo sapiens (human): 177
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Entry
177 CDS
T01001
Symbol
AGER, RAGE, SCARJ1, sRAGE
Name
(RefSeq) advanced glycosylation end-product specific receptor
KO
K19722
receptor for advanced glycosylation end products
Organism
hsa
Homo sapiens (human)
Pathway
hsa04148
Efferocytosis
hsa04613
Neutrophil extracellular trap formation
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06460
Alzheimer disease
nt06466
Pathways of neurodegeneration
Element
N00994
AGE-RAGE signaling pathway
N00996
Mutation-caused aberrant Abeta to AGE-RAGE signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
177 (AGER)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
177 (AGER)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
177 (AGER)
05022 Pathways of neurodegeneration - multiple diseases
177 (AGER)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
177 (AGER)
05415 Diabetic cardiomyopathy
177 (AGER)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
177 (AGER)
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Gene cluster
GFIT
Motif
Pfam:
C2-set_2
Ig_3
Ig_2
I-set
ig
V-set
Izumo-Ig
Ig_4
Ig_5
Motif
Other DBs
NCBI-GeneID:
177
NCBI-ProteinID:
NP_001127
OMIM:
600214
HGNC:
320
Ensembl:
ENSG00000204305
UniProt:
Q15109
A0A1U9X785
B4DNX3
Structure
PDB
PDBj
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All DBs
Position
6:complement(32180969..32184253)
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AA seq
404 aa
AA seq
DB search
MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI
PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH
PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL
VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS
CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV
ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
atggctgccggaacagcagttggagcctgggtgctggtcctcagtctgtggggggcagta
gtaggtgctcaaaacatcacagcccggattggcgagccactggtgctgaagtgtaagggg
gcccccaagaaaccaccccagcggctggaatggaaactgaacacaggccggacagaagct
tggaaggtcctgtctccccagggaggaggcccctgggacagtgtggctcgtgtccttccc
aacggctccctcttccttccggctgtcgggatccaggatgaggggattttccggtgccag
gcaatgaacaggaatggaaaggagaccaagtccaactaccgagtccgtgtctaccagatt
cctgggaagccagaaattgtagattctgcctctgaactcacggctggtgttcccaataag
gtggggacatgtgtgtcagagggaagctaccctgcagggactcttagctggcacttggat
gggaagcccctggtgcctaatgagaagggagtatctgtgaaggaacagaccaggagacac
cctgagacagggctcttcacactgcagtcggagctaatggtgaccccagcccggggagga
gatccccgtcccaccttctcctgtagcttcagcccaggccttccccgacaccgggccttg
cgcacagcccccatccagccccgtgtctgggagcctgtgcctctggaggaggtccaattg
gtggtggagccagaaggtggagcagtagctcctggtggaaccgtaaccctgacctgtgaa
gtccctgcccagccctctcctcaaatccactggatgaaggatggtgtgcccttgcccctt
ccccccagccctgtgctgatcctccctgagatagggcctcaggaccagggaacctacagc
tgtgtggccacccattccagccacgggccccaggaaagccgtgctgtcagcatcagcatc
atcgaaccaggcgaggaggggccaactgcaggctctgtgggaggatcagggctgggaact
ctagccctggccctggggatcctgggaggcctggggacagccgccctgctcattggggtc
atcttgtggcaaaggcggcaacgccgaggagaggagaggaaggccccagaaaaccaggag
gaagaggaggagcgtgcagaactgaatcagtcggaggaacctgaggcaggcgagagtagt
actggagggccttga
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