KEGG   ORTHOLOGY: K20518
Entry
K20518            Tight     KO                                     
Symbol
CAS
Name
copal-8-ol diphosphate hydratase / cis-abienol synthase [EC:4.2.1.133 4.2.3.140]
Pathway
map00904  Diterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R09967  geranylgeranyl-diphosphate hydratase (copal-8-ol-diphosphate-forming)
R10276  (13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate diphosphate-lyase (cis-abienol forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K20518  CAS; copal-8-ol diphosphate hydratase / cis-abienol synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.133  copal-8-ol diphosphate hydratase
     K20518  CAS; copal-8-ol diphosphate hydratase / cis-abienol synthase
   4.2.3  Acting on phosphates
    4.2.3.140  cis-abienol synthase
     K20518  CAS; copal-8-ol diphosphate hydratase / cis-abienol synthase
Genes
AG: AEL99953(CAS)
Reference
  Authors
Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J
  Title
Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production.
  Journal
J Biol Chem 287:12121-31 (2012)
DOI:10.1074/jbc.M111.317669
  Sequence
LinkDB

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