KEGG ORTHOLOGY: K20822

ORTHOLOGY: K20822

Entry

K20822                      KO

Symbol

MEF2BNB, BORCS8

Name

BLOC-1 related complex subunit 8

Disease

H02839

Infantile-onset neurodegeneration with optic atrophy and brain abnormalities

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K20822  MEF2BNB, BORCS8; BLOC-1 related complex subunit 8
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Arf GTPases and associated proteins
   BLOC-one-related complex (BORC)
    K20822  MEF2BNB, BORCS8; BLOC-1 related complex subunit 8

Genes

HSA:	729991(BORCS8)

PTR:	455871(BORCS8)

PPS:	100993479(BORCS8)

GGO:	101154202(BORCS8)

PON:	100568306(BORCS8)

PPYG:

129020546(BORCS8)

NLE:	101178495(BORCS8)

HMH:	116478737(BORCS8)

SSYN:

129459978(BORCS8)

MCC:	100568436(BORCS8)

MTHB:

126942360

CSAB:

103234208(BORCS8)

PANU:

100998950(BORCS8)

TGE:	112612360(BORCS8)

MLEU:

105547270(MEF2BNB)

RRO:	104680648(BORCS8)

RBB:	108515649(BORCS8)

TFN:	117076448(BORCS8)

PTEH:

111554220(BORCS8)

CANG:

105500369(MEF2BNB)

CJC:	100387099(BORCS8)

SBQ:	101043842(MEF2BNB)

CIMI:

108284581(BORCS8)

ANAN:

105710949(BORCS8)

CSYR:

103277264(BORCS8)

MMUR:

105858363(BORCS8)

LCAT:

123638357(BORCS8)

PCOQ:

105818199(MEF2BNB)

OGA:	100965748(BORCS8)

MMU:	72368(Borcs8)

MCAL:

110299825(Borcs8)

MPAH:

110336562(Borcs8)

RNO:	688966(Borcs8)

MCOC:

116069449(Borcs8)

ANU:	117721487(Borcs8)

ASYL:

127668403(Borcs8)

MUN:	110549172(Borcs8)

CGE:	100770611(Borcs8)

MAUA:

101825184(Borcs8)

PROB:

127217180(Borcs8)

PLEU:

114682877(Borcs8)

MORG:

121462750(Borcs8)

MFOT:

126491790

AAMP:

119811888(Borcs8)

NGI:	103726842(Borcs8)

HGL:	101713491(Borcs8)

CPOC:

100716619(Borcs8)

CCAN:

109699149(Borcs8)

DORD:

105994760(Mef2bnb)

DSP:	122100838(Borcs8)

DMER:

138817733(Borcs8)

PLOP:

125348947(Borcs8)

NCAR:

124968742

MMMA:

107145374(Borcs8)

ITI:	101978609(Borcs8)

OCU:

103346997

OPI:	101527504(BORCS8)

OCZ:	121160423(BORCS8)

TUP:	102471647(BORCS8)

GVR:	103588115(MEF2BNB)

CFA:	609124(BORCS8)

CLUD:

112666780(BORCS8)

VVP:	112912932(BORCS8)

VLG:	121495349(BORCS8)

NPO:	129522023(BORCS8)

AML:	100481555(BORCS8)

UMR:	103674920(BORCS8)

UAH:	113256746(BORCS8)

UAR:	123779889(BORCS8)

ELK:

111144358

LLV:

125081861

MPUF:

101685631(MEF2BNB)

MNP:	132011214(BORCS8)

MLK:	131823802(BORCS8)

NVS:	122909527(BORCS8)

ORO:	101384247(MEF2BNB)

EJU:	114196423(BORCS8)

ZCA:	113916559(BORCS8)

MLX:	118005657(BORCS8)

NSU:	110574397(BORCS8)

LWW:	102738220(BORCS8)

FCA:	101098287(BORCS8)

PYU:	121011049(BORCS8)

PCOO:

112852596(BORCS8)

PBG:	122487137(BORCS8)

LRUF:

124523543

LGF:	123605520(BORCS8)

AJU:

106969068

PTG:	102964069(BORCS8)

PPAD:

109247658(BORCS8)

PUC:

125930640

PLEZ:

122214220(BORCS8)

HHV:	120229251(BORCS8)

BTA:	100271850(BORCS8) 104975643

BOM:	138983902(BORCS8)

BIU:	109561384(BORCS8)

BBUB:

102392733(BORCS8) 102411796

BBIS:

104993856(MEF2BNB)

CHX:	102188577(BORCS8)

OAS:	101106256(BORCS8)

BTAX:

128050531(BORCS8)

CSUM:

138085989(BORCS8)

ODA:	120864297(BORCS8)

CCAD:

122440786(BORCS8)

MREE:

136155537(BORCS8)

OVR:	110131714(BORCS8)

MBEZ:

129558227(BORCS8)

SSC:	100620218(BORCS8)

CFR:	102505899(BORCS8)

CBAI:

105082601(MEF2BNB)

CDK:	105103712(BORCS8)

VPC:	102529193(BORCS8)

BACU:

102999354(BORCS8)

LVE:	103071216(MEF2BNB)

OOR:

101270309

GMF:

115865338

DDP:	138413843(BORCS8)

DLE:	111166541(BORCS8)

PCAD:

102980767(BORCS8)

PSIU:

116751390(BORCS8)

PPHC:

136121348(BORCS8)

NASI:

112414909(BORCS8)

ECB:	100071132(BORCS8)

EPZ:	103563797(BORCS8)

EAI:	106825458(BORCS8)

MYB:	102251928(BORCS8)

MYD:	102765377(BORCS8)

MMYO:

118658300(BORCS8)

MLF:	102442176(BORCS8)

MDT:	132234777(BORCS8)

MYUM:

139011165(BORCS8)

PKL:	118726000(BORCS8)

EFUS:

103299516(BORCS8)

MNA:	107535350(BORCS8)

DRO:	112305172(BORCS8)

AJM:	119040515(BORCS8)

PDIC:

114502848(BORCS8)

PHAS:

123828221(BORCS8)

MMF:	118615248(BORCS8)

PPAM:

129074994(BORCS8)

RFQ:	117038192(BORCS8)

PALE:

102888372(BORCS8)

PGIG:

120606588(BORCS8)

PVP:	105296566(BORCS8)

RAY:	107503730(BORCS8)

TOD:	119241151(BORCS8)

SARA:

101537580(MEF2BNB)

SFUM:

130028763(BORCS8)

SETR:

126030310(BORCS8)

LAV:	100677284(BORCS8)

TMU:

101357153

ETF:	101658892(BORCS8)

MDO:	100011398(BORCS8)

GAS:	123232158(BORCS8)

AFZ:

127544993

PCW:	110196131(BORCS8)

TVP:	118840274(BORCS8)

PBRV:

138160276(BORCS8)

MLAO:

141500753(BORCS8)

OAA:	100092153(BORCS8)

TACU:

119950040(BORCS8)

GGA:	426622(BORCS8)

PCOC:

116235769(BORCS8)

MGP:	100544368(BORCS8)

CJO:	107325616(BORCS8)

TPAI:

128088890(BORCS8)

LMUT:

125685015(BORCS8)

NMEL:

110388902(BORCS8)

ACYG:

106047933(BORCS8)

CATA:

118259936(BORCS8)

AFUL:

116499088(BORCS8)

TGU:	115490857(BORCS8)

PMOA:

120499073(BORCS8)

OTC:	121346919(BORCS8)

PRUF:

121355571(BORCS8)

ATRC:

139602379(BORCS8)

GFR:	102044103(BORCS8)

FAB:	101816229(BORCS8)

OMA:	130266885(BORCS8)

PHI:	102108603(BORCS8)

PMAJ:

107198795(BORCS8)

CCAE:

111940375(BORCS8)

CBRC:

103625558(BORCS8)

ACOE:

138099591(BORCS8)

ETL:	114071830(BORCS8)

ZLE:	135458752(BORCS8)

ACHL:

103809405(MEF2BNB)

SVG:	106859762(BORCS8)

HRT:	120747961(BORCS8)

CCIC:

134054339(BORCS8)

FPG:	101918188(BORCS8)

FCH:	102059477(BORCS8)

CCRI:

104165323(MEF2BNB)

NNT:	104406984(MEF2BNB)

SHAB:

115618089(BORCS8)

ACUN:

113489357(BORCS8)

TALA:

104358692(BORCS8)

ACHC:

115349616(BORCS8)

HALD:

104314148(MEF2BNB)

HLE:	104829126(MEF2BNB)

AGEN:

126041984

HHAR:

128148178(BORCS8)

GCL:

127025583

CSTI:

104558962(MEF2BNB)

LDI:	104344948(MEF2BNB)

MNB:	103781798(MEF2BNB)

DPUB:

104300769(MEF2BNB)

PPUS:

135192231(BORCS8)

AVIT:

104277456(MEF2BNB)

BRHI:

104497884(MEF2BNB)

EGZ:	104129792(BORCS8)

NNI:	104013681(MEF2BNB)

PCRI:

104032954(MEF2BNB)

PCAO:

104043275(MEF2BNB)

PADL:

103923279(MEF2BNB)

AFOR:

103899373(BORCS8)

FGA:	104078162(MEF2BNB)

CBOR:

142093964(BORCS8)

GSTE:

104254222(MEF2BNB)

CBOY:

140643645(BORCS8)

MAME:

142420356(BORCS8)

CLV:	102094663(BORCS8)

CNIC:

135999165(BORCS8)

MUI:	104535718(MEF2BNB)

PGUU:

104461280(MEF2BNB)

PLET:

104616911(MEF2BNB)

EHS:	104508192(MEF2BNB)

CMAC:

104475870(MEF2BNB)

CUCA:

104065767(BORCS8)

TEO:	104378971(MEF2BNB)

BREG:

104642630(MEF2BNB)

OHA:	104329910(MEF2BNB)

ACAR:

104523202(BORCS8)

CPEA:

104386470(MEF2BNB)

CVF:	104282040(MEF2BNB)

RTD:	128900751(BORCS8)

CRID:

134526395(BORCS8)

LMIC:

141734292(BORCS8)

AAM:	106482270(BORCS8)

AROW:

112965587(BORCS8)

NPD:	112946919(BORCS8)

TGT:	104578030(MEF2BNB)

DNE:	112993209(BORCS8)

SCAM:

104152310(MEF2BNB)

ASN:	102383373(BORCS8)

AMJ:	102561789(BORCS8)

CPOO:

109312333(BORCS8)

GGN:	109294970(BORCS8)

PSS:	102448118(BORCS8)

CIZ:	142002086(BORCS8)

CMY:	122461307(BORCS8)

DCC:	122455392(BORCS8)

CPIC:

101932361(BORCS8)

TST:	117868760(BORCS8)

MRV:	120391673(BORCS8)

ASAO:

132781019(BORCS8)

PVT:	110072548(BORCS8)

SUND:

121916726(BORCS8)

PBI:	103056974(BORCS8)

PMUR:

107282890(BORCS8)

CTIG:

120296892 120296900

PGUT:

117680064(BORCS8)

PCAE:

139308316(BORCS8)

APRI:

131188276(BORCS8)

PTEX:

113435295(BORCS8)

NSS:	113422296(BORCS8)

VKO:	123036598(BORCS8)

PMUA:

114588385(BORCS8)

PRAF:

128405684(BORCS8)

ZVI:	118087631(BORCS8)

HCG:	128346809(BORCS8)

STOW:

125432590(BORCS8)

EMC:	129329978(BORCS8)

XLA:	100616538(borcs8.S)

XTR:	100490313(borcs8)

NPR:	108796866(BORCS8)

RTEM:

120909087(BORCS8)

ACAT:

141103225(BORCS8)

BBUF:

120991586(BORCS8)

BGAR:

122931452(BORCS8)

DTC:	141058917(BORCS8)

PWL:	138267956(BORCS8)

MUO:	115479726(BORCS8)

GSH:	117364808(BORCS8)

DRE:	558180(borcs8)

SRX:	107719619(borcs8) 107728595

SANH:

107655239(borcs8)

SGH:	107554813 107599453

CCAR:

109047848 109096641(borcs8)

CAUA:

113039605 113064892 113081489

CGIB:

127943144 127988070

PTET:

122327677(borcs8)

LROH:

127153972(borcs8)

GRF:	141339068(borcs8)

OMC:	131531419(borcs8)

PPRM:

120486342(borcs8)

RKG:	130089236(borcs8)

MAMB:

125252201(borcs8)

CIDE:

127520782

CERY:

137027728(borcs8)

MASI:

127438220 127439075

TROS:

130549034(borcs8)

TDW:	130429623(borcs8)

MANU:

129454291(borcs8)

PDAB:

135727969(borcs8)

IPU:

108271275

IFU:	128613879(borcs8)

PHYP:

113525960(borcs8)

SMEO:

124391216(borcs8)

TFD:	113657828(borcs8)

TVC:	132852749(borcs8)

CGAR:

128542912(borcs8)

NGRA:

132899478(borcs8)

TRN:	134331322(borcs8)

AMEX:

103043736(borcs8)

CMAO:

118819044(borcs8)

EEE:	113576198(borcs8)

CHAR:

105889684(borcs8)

SPIL:

134101788(borcs8)

ASAD:

121724883(borcs8)

TRU:	101069089(borcs8)

TFS:	130528604(borcs8)

TNG:	GSTEN00024711G001

LCO:	104918764(borcs8)

NCC:	104950595(mef2bnb)

TBEN:

117495951(borcs8)

CGOB:

115006895(borcs8)

PGEO:

117445472(borcs8)

GACU:

117546151(borcs8)

EMAC:

134869051(borcs8)

ELY:	117253903(borcs8)

EFO:	125896354(borcs8)

PLEP:

121939290(borcs8)

SLUC:

116063395(borcs8)

ECRA:

117950429(borcs8)

ESP:	116695907(borcs8)

PFLV:

114561089(borcs8)

GAT:	120823996(borcs8)

PPUG:

119216585(borcs8)

AFB:	129094501(borcs8)

PSWI:

130194083(borcs8)

CANA:

137794572(borcs8)

CVE:	137866469(borcs8)

MSAM:

119900937(borcs8)

SCHU:

122877396(borcs8)

CUD:	121512141(borcs8)

SPUL:

138607193(borcs8)

LMIX:

132962657(borcs8)

HTC:	141788703(borcs8)

ALAT:

119028118(borcs8)

ASTR:

137598831(borcs8)

MZE:	101484143(borcs8)

ONL:	100695005(borcs8)

OAU:	116327887(borcs8)

OLA:	101171506(borcs8)

OML:	112136888(borcs8)

CSAI:

133458154(borcs8)

XMA:	102220753(borcs8)

XCO:	114151144(borcs8)

XHE:	116726143(borcs8)

PRET:

103463700(borcs8)

PFOR:

103150422(borcs8)

PLAI:

106948922(borcs8)

PMEI:

106925126(borcs8)

GAF:	122838448(borcs8)

PPRL:

129373681(borcs8)

CVG:	107100791(borcs8)

CTUL:

119786758(borcs8)

GMU:	124873649(borcs8)

NFU:	107396484(borcs8)

KMR:	108230549(borcs8)

ALIM:

106536824(borcs8)

NWH:	119407978(borcs8)

AOCE:

111570704(borcs8)

EJA:	138198629(borcs8)

BFRE:

138618849(borcs8)

MCEP:

125009313(borcs8)

CSEM:

103376771(borcs8)

POV:	109625706(borcs8)

SSEN:

122780621(borcs8)

SSOE:

131465621(borcs8)

HHIP:

117760215(borcs8)

HSP:	124854768(borcs8)

PPLT:

128447618(borcs8)

SMAU:

118317805(borcs8)

LCF:

108879138

SDU:	111231947(borcs8)

SLAL:

111653547(borcs8)

XGL:	120790514(borcs8)

HCQ:	109532147(borcs8)

SSCV:

125971138(borcs8)

SBIA:

133503948(borcs8)

PEE:	133406165(borcs8)

PTAO:

133481422(borcs8)

BPEC:

110174070(borcs8)

ENY:	140353772(borcs8)

MALB:

109966985(borcs8)

BSPL:

114854080(borcs8)

SJO:	128362184(borcs8)

SSCO:

133984506(borcs8)

TTY:	137188016(borcs8)

GMH:	115555580(borcs8)

SASA:

106573586(borcs8)

STRU:

115151794(borcs8)

OTW:	112244779(borcs8)

OMY:	110506565(borcs8)

ONE:	115109246(borcs8)

OKI:	109889218(borcs8)

OKE:	118401398(borcs8)

OMM:	135524562(borcs8)

OCLA:

139381138

SALP:

111952528(borcs8)

SNH:	120053788(borcs8)

SFON:

129867244(borcs8)

CCLU:

121576776(borcs8)

ELS:	105011510(borcs8)

OEP:	134010955(borcs8)

SFM:	108921334(borcs8)

PKI:	111836533(borcs8)

AANG:

118226467(borcs8)

AROT:

135253016(borcs8)

CCOG:

133126233(borcs8)

LOC:	102683682(borcs8)

PSPA:

121301578 121301653(borcs8)

ARUT:

117428985 117966251

PSEX:

120537626(borcs8)

LCM:	102361352(BORCS8)

CMK:	103181986(borcs8)

CPLA:

122565452(borcs8)

HOC:	132828885(borcs8)

SCAU:

119953000(borcs8)

LERI:

129711198(borcs8)

HAKA:

140739693(borcs8)

PMRN:

116955048

LRJ:	133345204(BORCS8) 133358218

BBEL:

CIN:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG32590(CG32590)

DER:

6550730

DSE:

6619560

DSI:	Dsimw501_GD15834(Dsim_GD15834)

DYA:	Dyak_GE16097

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:	124459666 124461442 124461447 26529275 6637627

DGR:

6566875

DMO:	Dmoj_GI25840

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ010492

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:	100746424 100749811

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

126919141 126923681 126923683 126923685 126923687 126923689 126923756

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:	115885709 115885729

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_201406

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:	128996903 128996957

PHU:	Phum_PHUM097450

FOC:	113202872 113206121

TPAL:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_310388

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:	128696423 138851592

PTRU:

123504725

ESN:

126996504

MNZ:	135211773 135211870

MRJ:

PORN:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107360097 112538566

DPTE:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

CEL:	CELE_K11B4.2(blos-9)

CBR:

CBG_19713

CRQ:	GCK72_001438

NAI:	NECAME_08749

LOA:	LOAG_00137

TSP:

Tsp_05541

HRO:	HELRODRAFT_152908

LGI:	LOTGIDRAFT_230826

BGT:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

LJP:

LAK:

SMM:	Smp_127660

OVI:	T265_07078

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

AQU:

APRO:

MBR:	MONBRDRAFT_31026

TBG:	TbgDal_VII7875

» show all

Reference

PMID:25898167

Authors

Pu J, Schindler C, Jia R, Jarnik M, Backlund P, Bonifacino JS

Title

BORC, a multisubunit complex that regulates lysosome positioning.

Journal

Dev Cell 33:176-88 (2015)
DOI:10.1016/j.devcel.2015.02.011

Sequence

[hsa:729991]

LinkDB

DBGET integrated database retrieval system