KEGG ORTHOLOGY: K21124

ORTHOLOGY: K21124

Entry

K21124                      KO

Symbol

TRAF3IP2, ACT1

Name

adaptor protein CIKS

Pathway

map04218

Cellular senescence

map04657

IL-17 signaling pathway

Disease

H01109

Chronic mucocutaneous candidiasis

H01656

Psoriasis

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    K21124  TRAF3IP2, ACT1; adaptor protein CIKS
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    K21124  TRAF3IP2, ACT1; adaptor protein CIKS

Genes

HSA:	10758(TRAF3IP2)

PPS:	100971252(TRAF3IP2)

GGO:	101141142(TRAF3IP2)

PON:	100439347(TRAF3IP2)

PPYG:

129038806(TRAF3IP2)

NLE:	100584315(TRAF3IP2)

HMH:	116471006(TRAF3IP2)

SSYN:

129472006(TRAF3IP2)

MCC:	697530(TRAF3IP2)

MCF:	102124948(TRAF3IP2)

MTHB:

126953588

MNI:	105492086(TRAF3IP2)

CSAB:

103240582(TRAF3IP2)

CATY:

105581385(TRAF3IP2)

PANU:

101010700(TRAF3IP2)

TGE:	112622081(TRAF3IP2)

MLEU:

105532447(TRAF3IP2)

RRO:	104668859(TRAF3IP2)

RBB:	108512058(TRAF3IP2)

TFN:	117096934(TRAF3IP2)

PTEH:

111547325(TRAF3IP2)

CANG:

105506743(TRAF3IP2)

CJC:	100390719(TRAF3IP2)

SBQ:	101050681(TRAF3IP2)

CIMI:

108289730(TRAF3IP2)

ANAN:

105707436(TRAF3IP2)

CSYR:

103261353(TRAF3IP2)

MMUR:

105864899(TRAF3IP2)

LCAT:

123633173(TRAF3IP2)

PCOQ:

105809086(TRAF3IP2)

OGA:	100954229(TRAF3IP2)

MMU:	103213(Traf3ip2)

MCAL:

110303775(Traf3ip2)

MPAH:

110326346(Traf3ip2)

RNO:	361857(Traf3ip2)

MCOC:

116075357(Traf3ip2)

ANU:	117724415(Traf3ip2)

ASYL:

127669524(Traf3ip2)

MUN:	110561018(Traf3ip2)

CGE:	100774308(Traf3ip2)

MAUA:

101833509(Traf3ip2)

PROB:

127215152(Traf3ip2)

PLEU:

114696885(Traf3ip2)

MORG:

121449558(Traf3ip2)

MFOT:

126499081

AAMP:

119820757(Traf3ip2)

NGI:	103749535(Traf3ip2)

HGL:	101721876(Traf3ip2)

CPOC:

100728787(Traf3ip2)

CCAN:

109695351(Traf3ip2)

DORD:

105998187(Traf3ip2)

DSP:	122123086(Traf3ip2)

PLOP:

125357193(Traf3ip2)

NCAR:

124988181

MMMA:

107154637(Traf3ip2)

ITI:	101964605(Traf3ip2)

OCU:	100338995(TRAF3IP2)

OPI:	101517707(TRAF3IP2)

TUP:	102497868(TRAF3IP2)

GVR:	103596897(TRAF3IP2)

CFA:	475031(TRAF3IP2)

CLUD:

112658472(TRAF3IP2)

VVP:	112925184(TRAF3IP2)

VLG:	121481454(TRAF3IP2)

NPO:	129512570(TRAF3IP2)

AML:	100473939(TRAF3IP2)

UMR:	103676992(TRAF3IP2)

UAR:	123792960(TRAF3IP2)

ELK:

111158219

LLV:

125102896

MPUF:

101674127(TRAF3IP2)

MNP:	132018369(TRAF3IP2)

MLK:	131833498(TRAF3IP2)

NVS:	122903487(TRAF3IP2)

ORO:	101386697(TRAF3IP2)

EJU:	114209905(TRAF3IP2)

ZCA:	113926450(TRAF3IP2)

MLX:	118001611(TRAF3IP2)

NSU:	110583331(TRAF3IP2)

LWW:	102730646(TRAF3IP2)

FCA:	101085125(TRAF3IP2)

PYU:	121029908(TRAF3IP2)

PCOO:

112862350(TRAF3IP2)

PBG:	122489875(TRAF3IP2)

PVIV:

125165612(TRAF3IP2)

LRUF:

124528168

PTG:	102957091(TRAF3IP2)

PPAD:

109263552(TRAF3IP2)

PUC:

125938808

AJU:

106968907

HHV:	120245255(TRAF3IP2)

BTA:	616801(TRAF3IP2)

BOM:	102284665(TRAF3IP2)

BIU:	109563812(TRAF3IP2)

BBUB:

102414513(TRAF3IP2)

BBIS:

105000639(TRAF3IP2)

CHX:	102180672(TRAF3IP2)

OAS:	101109809(TRAF3IP2)

BTAX:

128053227(TRAF3IP2)

CSUM:

138089636(TRAF3IP2)

ODA:	120862490(TRAF3IP2)

CCAD:

122422914(TRAF3IP2)

MREE:

136150843(TRAF3IP2)

MBEZ:

129560711(TRAF3IP2)

SSC:	100157000(TRAF3IP2)

CFR:	102507269(TRAF3IP2)

CBAI:

105077133(TRAF3IP2)

CDK:	105099210(TRAF3IP2)

VPC:	102531133(TRAF3IP2)

BACU:

103011789(TRAF3IP2)

BMUS:

118905073(TRAF3IP2)

LVE:	103078917(TRAF3IP2)

OOR:	101279868(TRAF3IP2)

DLE:	111164704(TRAF3IP2)

PCAD:

102974872(TRAF3IP2)

PSIU:

116763222(TRAF3IP2)

NASI:

112396947(TRAF3IP2)

ECB:	100066812(TRAF3IP2)

EPZ:	103547548(TRAF3IP2)

EAI:	106847053(TRAF3IP2)

MYB:	102244206(TRAF3IP2)

MYD:	102752830(TRAF3IP2)

MMYO:

118660585(TRAF3IP2) 118662102

MDT:	132236987(TRAF3IP2)

PKL:	118705201(TRAF3IP2)

EFUS:

103302134(TRAF3IP2)

MNA:	107540695(TRAF3IP2)

DRO:	112297019(TRAF3IP2)

SHON:

119000184(TRAF3IP2)

AJM:	119059418(TRAF3IP2)

PDIC:

114495522(TRAF3IP2)

PHAS:

123821640(TRAF3IP2)

MMF:	118620688(TRAF3IP2)

PPAM:

129067707(TRAF3IP2)

HAI:	109384749(TRAF3IP2)

RFQ:	117020416(TRAF3IP2)

PALE:

102896596(TRAF3IP2)

PGIG:

120608565(TRAF3IP2)

PVP:	105295227(TRAF3IP2)

RAY:	107506310(TRAF3IP2)

MJV:	108396081(TRAF3IP2)

TOD:	119252789(TRAF3IP2)

SARA:

101537979(TRAF3IP2)

SFUM:

130033660(TRAF3IP2)

SETR:

126005872(TRAF3IP2)

LAV:	100676384(TRAF3IP2)

TMU:

101361676

ETF:	101664011(TRAF3IP2)

DNM:	101447251(TRAF3IP2)

MDO:	100029382(TRAF3IP2)

GAS:	123246566(TRAF3IP2)

SHR:	100922830(TRAF3IP2)

AFZ:

127562102

PCW:	110222879(TRAF3IP2)

TVP:	118856310(TRAF3IP2)

PBRV:

138152937(TRAF3IP2)

OAA:	100093440(TRAF3IP2)

GGA:	421752(TRAF3IP2)

PCOC:

116240391(TRAF3IP2)

MGP:	100542213(TRAF3IP2)

CJO:	107311786(TRAF3IP2)

TPAI:

128078446(TRAF3IP2)

LMUT:

125688915(TRAF3IP2)

NMEL:

110397035(TRAF3IP2)

APLA:

101800471(TRAF3IP2)

ACYG:

106032577(TRAF3IP2)

CATA:

118244021(TRAF3IP2)

AFUL:

116487787(TRAF3IP2)

TGU:	100226375(TRAF3IP2)

LSR:	110484649(TRAF3IP2)

SCAN:

103818573(TRAF3IP2)

PMOA:

120510644(TRAF3IP2)

OTC:	121341434(TRAF3IP2)

PRUF:

121359219(TRAF3IP2)

GFR:	102037476(TRAF3IP2)

FAB:	101806875(TRAF3IP2)

OMA:	130251461(TRAF3IP2)

PHI:	102112913(TRAF3IP2)

PMAJ:

107202330(TRAF3IP2)

CCAE:

111927156(TRAF3IP2)

CCW:	104691317(TRAF3IP2)

CBRC:

103619268(TRAF3IP2)

ACOE:

138108383(TRAF3IP2)

ETL:	114062025(TRAF3IP2)

ZAB:	102067250(TRAF3IP2)

ZLE:	135445449(TRAF3IP2)

ACHL:

103808986(TRAF3IP2)

SVG:	106854995(TRAF3IP2)

MMEA:

130589057(TRAF3IP2)

HRT:	120750962(TRAF3IP2)

SATI:

136359019(TRAF3IP2)

FPG:	101924699(TRAF3IP2)

FCH:	102057938(TRAF3IP2)

CCRI:

104158927

NNT:	104402136(TRAF3IP2)

SHAB:

115609362(TRAF3IP2)

ACUN:

113478857(TRAF3IP2)

ACHC:

115349447(TRAF3IP2)

HALD:

104317514(TRAF3IP2)

HLE:	104828170(TRAF3IP2)

AGEN:

126046043

HHAR:

128139205(TRAF3IP2)

GCL:

127015008

CSTI:

104555372(TRAF3IP2)

LDI:	104348796(TRAF3IP2)

MNB:	103770877(TRAF3IP2)

DPUB:

104296615(TRAF3IP2)

PPUS:

135189653(TRAF3IP2)

AVIT:

104269055

BRHI:

104498542(TRAF3IP2)

EGZ:	104131980(TRAF3IP2)

NNI:	104011132(TRAF3IP2)

PCRI:

104032329(TRAF3IP2)

PCAO:

104047177

PADL:

103918979(TRAF3IP2)

AFOR:

103907055(TRAF3IP2)

FGA:	104075414(TRAF3IP2)

GSTE:

104262206

CLV:	102095279(TRAF3IP2)

MUI:	104544881(TRAF3IP2)

PGUU:

104470837

PLET:

104626506

EHS:	104516166(TRAF3IP2)

CMAC:

104477915

CUCA:

104062748(TRAF3IP2)

TEO:

104372047

BREG:

104637009(TRAF3IP2)

OHA:	104332677(TRAF3IP2)

ACAR:

104532226(TRAF3IP2)

CPEA:

104398293(TRAF3IP2)

CVF:	104294055(TRAF3IP2)

RTD:	128907920(TRAF3IP2)

AAM:	106489678(TRAF3IP2)

AROW:

112965976(TRAF3IP2)

NPD:	112948468(TRAF3IP2)

TGT:	104569806(TRAF3IP2)

DNE:	112995120(TRAF3IP2)

SCAM:

104149056(TRAF3IP2)

ASN:	102384842(TRAF3IP2)

AMJ:	102575300(TRAF3IP2)

CPOO:

109311943(TRAF3IP2)

GGN:	109299591(TRAF3IP2)

PSS:	102463637(TRAF3IP2)

CMY:	102934991(TRAF3IP2)

CCAY:

125634269(TRAF3IP2)

DCC:	119853174(TRAF3IP2)

CPIC:

101950571(TRAF3IP2)

TST:	117875020(TRAF3IP2)

CABI:

116820268(TRAF3IP2)

MRV:	120400594(TRAF3IP2)

ACS:	100565289(traf3ip2)

ASAO:

132760875(TRAF3IP2)

PVT:	110085311(TRAF3IP2)

SUND:

121918941(TRAF3IP2)

PBI:	103061504(TRAF3IP2)

PMUR:

107287163(TRAF3IP2)

CTIG:

120311562(TRAF3IP2)

TSR:	106540115(TRAF3IP2)

PGUT:

117660858(TRAF3IP2)

APRI:

131193553(TRAF3IP2)

PTEX:

113455318(TRAF3IP2)

NSS:	113411557(TRAF3IP2)

VKO:	123021540(TRAF3IP2)

PMUA:

114594050(TRAF3IP2)

PRAF:

128410446(TRAF3IP2)

ZVI:	118082129(TRAF3IP2)

HCG:	128349502(TRAF3IP2)

GJA:	107118445(TRAF3IP2)

STOW:

125437763(TRAF3IP2)

EMC:	129327582(TRAF3IP2)

XLA:

108716826

XTR:	105947414 549319(traf3ip3)

RTEM:

120937219(TRAF3IP2)

BBUF:

120998270(TRAF3IP2)

BGAR:

122934360(TRAF3IP2)

MUO:	115458732 115467343(TRAF3IP2)

GSH:	117358199(TRAF3IP2)

DRE:	606616(traf3ip2a)

SRX:	107705109 107746556

SANH:

107677734

SGH:

107550525

CCAR:

109073389 109087414

CAUA:

113055402 113055601 113083506 113087667 113111315

CGIB:

127938335

PTET:

122325046

LROH:

127183462(traf3ip2a)

OMC:	131527611(traf3ip2a)

PPRM:

120476178(traf3ip2a)

RKG:	130089266(traf3ip2a)

MAMB:

125261223

CERY:

137019330(traf3ip2a)

MASI:

127410242

TROS:

130566213(traf3ip2a)

TDW:	130434384(traf3ip2a)

IPU:	108255526(traf3ip2a)

IFU:	128617950(traf3ip2a)

PHYP:

113525196(traf3ip2)

SMEO:

124401229(traf3ip2a)

TFD:	113661144(traf3ip2a)

TVC:	132855020(traf3ip2a)

TRN:	134319792(traf3ip2a)

AMEX:

103025743(traf3ip2a)

CMAO:

118816037(traf3ip2a)

EEE:	113586229(traf3ip2)

CHAR:

105894820(traf3ip2a) 105905653

SPIL:

134098278(traf3ip2a)

TRU:	101066734 101071926(traf3ip2) 105418817

TFS:	130528523(traf3ip2l) 130540074(traf3ip2a)

TNG:	GSTEN00010459G001

LCO:	104922927(traf3ip2) 104928278 104931616

NCC:	104959542 104960497

TBEN:

117476503 117487556 117498571(traf3ip2a)

CGOB:

115003731(traf3ip2) 115027271

PGEO:

117439758(traf3ip2a) 117468121

GACU:

117540608 117557150(traf3ip2a) 117560712

EMAC:

134877133(traf3ip2a) 134881945

ELY:	117254306(traf3ip2l) 117266930 117270575(traf3ip2a)

EFO:	125896272(traf3ip2l) 125897176(traf3ip2a) 125900803

PLEP:

121941333(traf3ip2l) 121954033 121956002(traf3ip2a)

SLUC:

116040348(traf3ip2a) 116057293 116058737(traf3ip2l)

ECRA:

117936239 117950096(traf3ip2l) 117961953(traf3ip2a)

ESP:	116669658 116679857 116696058 116705956(traf3ip2)

PFLV:

114561911 114573750(traf3ip2)

GAT:	120807867(traf3ip2a) 120824106 120833022

PPUG:

119194809(traf3ip2a) 119216442 119227894

AFB:	129094835(traf3ip2l) 129103045 129107379(traf3ip2a)

CLUM:

117725122 117727890(traf3ip2a) 117730078(traf3ip2l)

PSWI:

130193502(traf3ip2l) 130202305

CANA:

137785842(traf3ip2a) 137795533(traf3ip2l)

CVE:	137871029(traf3ip2a) 137877848 137883763(traf3ip2l)

MSAM:

119901116(traf3ip2l) 119909311(traf3ip2a) 119909883

SCHU:

122862054 122862804(traf3ip2a) 122877320(traf3ip2l)

CUD:	121511807(traf3ip2l) 121521638(traf3ip2a)

SPUL:

138585126(traf3ip2a) 138591200 138607667(traf3ip2l)

LMIX:

132956501(traf3ip2l) 132985343(traf3ip2a) 132993068

ALAT:

119004878 119012243 119028223(traf3ip2l)

ASTR:

137598431(traf3ip2l) 137611369 137613744(traf3ip2a)

MZE:	101474344 101475279 101480541(traf3ip2)

ONL:	100691667(traf3ip2) 100701435 100709415

OAU:	116317257 116326103 116331063(traf3ip2l)

OLA:	101157261 101164045 101169831(traf3ip2)

OML:	112146888 112150481 112157698(traf3ip2a)

CSAI:

133418575(traf3ip2a) 133458229(traf3ip2l) 133462580

XMA:	102217271 102220013(traf3ip2)

XCO:	114150673 114158473(traf3ip2)

XHE:	116725718 116734540(traf3ip2)

PRET:

103458012(traf3ip2) 103463890

PFOR:

103140739(traf3ip2) 103149353

PLAI:

106941599 106958581(traf3ip2)

PMEI:

106903329 106933514

GAF:	122824830(traf3ip2a) 122838792(traf3ip2l)

PPRL:

129369190(traf3ip2a) 129371721(traf3ip2l)

CVG:	107092359(traf3ip2) 107095771

CTUL:

119777071 119790774(traf3ip2a)

GMU:	124874448(traf3ip2l) 124882156(traf3ip2a)

NFU:	107395048 107396022(traf3ip2)

KMR:	108240216 108248895(traf3ip2a)

ALIM:

106512455 106529784

NWH:	119408198 119418722(traf3ip2a)

AOCE:

111563654 111581773

EJA:	138198963(traf3ip2l) 138200098 138205680(traf3ip2a)

BFRE:

138624060(traf3ip2l) 138625089(traf3ip2a) 138625919

MCEP:

124998654(traf3ip2a) 125009367(traf3ip2l) 125023381

CSEM:

103378345 103380633(traf3ip2) 103392802

POV:	109625478 109632404(traf3ip2) 109636262

SSEN:

122783073 122784449(traf3ip2a)

HHIP:

117755527 117758615(traf3ip2a) 117760078(traf3ip2l)

HSP:	118099092(traf3ip2a) 118115950 118120598(traf3ip2l)

PPLT:

128447933(traf3ip2l) 128451477 128460040(traf3ip2a)

SMAU:

118286548 118290520(traf3ip2a) 118317748(traf3ip2l)

LCF:	108875027 108899325(traf3ip2a)

SDU:	111226030 111231802 111240430(traf3ip2)

SLAL:

111651010 111671716 111672905(traf3ip2)

XGL:	120789098 120791171(traf3ip2l) 120795614

HCQ:	109517222 109524858(traf3ip2) 109532280

SSCV:

125968622(traf3ip2l) 125981083 125989791(traf3ip2a)

SBIA:

133496691(traf3ip2a) 133503169(traf3ip2l) 133513790

PEE:	133405917(traf3ip2l) 133412412 133416930(traf3ip2a)

PTAO:

133468222(traf3ip2a) 133480329(traf3ip2l) 133487935

BPEC:

110153664 110154016(traf3ip2) 110154788

MALB:

109962055 109968083(traf3ip2)

BSPL:

114849060 114849391(traf3ip2a) 114854320(traf3ip2l)

SJO:	128361786(traf3ip2l) 128376883(traf3ip2a)

SSCO:

133985072(traf3ip2l) 133997403(traf3ip2a)

SASA:

106607737 106610386

STRU:

115152905 115158934 115194116

OTW:	112217531(traf3ip2a) 112248139(traf3ip2l) 112259034

OMY:	110502930 110522146(traf3ip2a) 110524911(traf3ip2l)

OGO:	123995660(traf3ip2a) 123996876 124038575

ONE:	115115475 115123060 115139500

OKI:	109866122 109880614 109900048

OKE:	118386811(traf3ip2a) 118387352

SALP:

111978373 112068188

SNH:	120019669(traf3ip2a) 120046815 120054385

CCLU:

121534203 121549003(traf3ip2a) 121577517

ELS:	105017890(traf3ip2) 105028154

SFM:	108921806 108933218

PKI:	111838187 111857867

AANG:

118222437(traf3ip2a) 118224137

CCOG:

133124373 133136213(traf3ip2a)

LOC:	102691757 102693738(traf3ip2)

PSPA:

121315479 121320534(traf3ip2l) 121327902

ARUT:

117402537(traf3ip2a) 117406040 117406852(traf3ip2l)

PSEX:

120523562(traf3ip2l) 120525551(traf3ip2a)

LCM:	102354220(TRAF3IP2) 102358239

CMK:	103178952(traf3ip2a) 103180097

RTP:	109916525(traf3ip2a)

CPLA:

122540049 122555309

HOC:	132821129(traf3ip2l) 132836373(traf3ip2a)

LERI:

129694965(traf3ip2a)

PMRN:

116953237

LRJ:

133354604

BFO:	118413133 118414719

CIN:

SCLV:

GAE:

OSN:

XEN:	124445418 124447407

» show all

Reference

PMID:10962024

Authors

Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR

Title

Act1, an NF-kappa B-activating protein.

Journal

Proc Natl Acad Sci U S A 97:10489-93 (2000)
DOI:10.1073/pnas.160265197

Sequence

[hsa:10758]

LinkDB

DBGET integrated database retrieval system