KEGG ORTHOLOGY: K22672

ORTHOLOGY: K22672

Entry

K22672                      KO

Symbol

GDF3

Name

growth differentiation factor 3

Pathway

map04060

Cytokine-cytokine receptor interaction

Disease

H00852

Klippel-Feil syndrome

H01027

Microphthalmia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K22672  GDF3; growth differentiation factor 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K22672  GDF3; growth differentiation factor 3
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Transforming growth factors (RSTK binding)
   K22672  GDF3; growth differentiation factor 3

Genes

HSA:	9573(GDF3)

PTR:	451817(GDF3)

PPS:	100988098(GDF3)

GGO:	101151622(GDF3)

PON:	100461404(GDF3)

PPYG:

129010272(GDF3)

NLE:	100606028(GDF3)

HMH:	116472632(GDF3)

SSYN:

129483433(GDF3)

MCC:	114678790 715605(GDF3)

MCF:	102146403(GDF3)

MTHB:

126931377 126957151

MNI:	105484239(GDF3) 105499406

CSAB:

103218510(GDF3)

CATY:

105583072(GDF3)

PANU:

101015395(GDF3)

TGE:	112635063(GDF3)

MLEU:

105541833(GDF3)

RRO:	104681676(GDF3)

RBB:	108530997 108542011(GDF3)

TFN:	117091116(GDF3)

PTEH:

111555971(GDF3)

CANG:

105519292(GDF3)

CJC:	100394876(GDF3)

SBQ:	101039799(GDF3)

CIMI:

108291837(GDF3) 119474123

ANAN:

105732606(GDF3)

CSYR:

103269905

MMUR:

105878290(GDF3)

LCAT:

123640047(GDF3)

ERUF:

138397107(GDF3)

PCOQ:

105805056(GDF3)

OGA:	100942326(GDF3)

MMU:	14562(Gdf3)

MCAL:

110297004(Gdf3)

MPAH:

110317217(Gdf3)

RNO:	500311(Gdf3)

MCOC:

116098319(Gdf3)

ANU:	117715501(Gdf3)

ASYL:

127677625(Gdf3)

MMIU:

308418638(GDF3)

MUN:	110556281(Gdf3)

CGE:	100763238(Gdf3)

MAUA:

101840876(Gdf3)

PROB:

127221130 127236107(Gdf3)

PLEU:

114683498(Gdf3) 119088756

PMAV:

102918435(Gdf3)

MORG:

121465991(Gdf3)

MFOT:

126507985 126514811

AAMP:

119806244(Gdf3) 119824285

CNL:	130889378(Gdf3)

NGI:	103727470(Gdf3)

CPOC:

100730461 100733509(Gdf3)

CCAN:

109684122(Gdf3)

NCAR:

124981998

SVUL:

306662043(GDF3)

MMMA:

107159926(Gdf3) 125615737

ITI:	101964649(Gdf3) 120885331

SCIL:

308658746(GDF3)

OCU:	100346534 103349623

OPI:	101534905(GDF3)

OCZ:	121154395 121155540(GDF3)

TUP:	102477246(GDF3)

GVR:	103597925(GDF3)

CFA:	477702(GDF3)

CLUD:

112675396(GDF3)

VVP:	112917583(GDF3)

VLG:	121479862(GDF3)

NPO:

129507341

AML:	100474590(GDF3) 100484470

UMR:	103669185(GDF3)

UAH:	113258088(GDF3)

UAR:	123781603(GDF3)

ELK:

111142291

LLV:

125106971

MPUF:

101690832(GDF3)

MNP:	132020271(GDF3)

MLK:	131839811(GDF3)

NVS:	122891148(GDF3)

MMAQ:

308348193(GDF3)

ORO:	101375684(GDF3)

EJU:	114221618(GDF3)

ZCA:	113922273(GDF3)

MLX:	118025442(GDF3)

MANO:

123841466(GDF3)

NSU:	110581004(GDF3)

LWW:	102745055(GDF3)

FCA:	101097251(GDF3)

PYU:	121022062(GDF3)

PCOO:

112867754(GDF3)

PBG:	122473268(GDF3)

PVIV:

125169532(GDF3)

LRUF:

124501313

LGF:	123591263(GDF3)

AJU:

106965479

PTG:	102965420(GDF3)

PPAD:

109276367(GDF3)

PUC:

125920083

PLEZ:

122225620(GDF3)

HHV:	120222700(GDF3)

CCRU:

144227406(GDF3)

BTA:	786521(GDF3)

BOM:	102271814(GDF3)

BIU:	109559697(GDF3)

BJV:	133226724 133248171(GDF3)

BBUB:

102406107(GDF3)

BKE:	129644477(GDF3)

BBIS:

104995479(GDF3)

CHX:	102182110(GDF3)

OAS:	101103967(GDF3)

OCAN:

138438341(GDF3)

BTAX:

128048943(GDF3)

CSUM:

138078770(GDF3)

ODA:	120858786(GDF3)

CCAD:

122423130 122423131

MREE:

136168283(GDF3)

OVR:	110142002(GDF3)

MBEZ:

129537259(GDF3)

SSC:	100510963(GDF3)

CFR:	102504374(GDF3)

CBAI:

105062173(GDF3)

CDK:	105098174(GDF3)

VPC:	102530611(GDF3)

BACU:

103010760(GDF3)

BMUS:

118901544(GDF3)

LVE:	103080190(GDF3)

OOR:	101273040(GDF3)

LALB:

132529167(GDF3)

GMF:	115840932(GDF3)

DDP:	132434404(GDF3)

SCOO:

307194977(ACYUVP_020250)

PCRS:

137201598(GDF3)

DLE:	111176726(GDF3)

PCAD:

102982830(GDF3)

PSIU:

116761305(GDF3)

PPHC:

136131509(GDF3)

NASI:

112391942(GDF3)

HAMP:

307060690(GDF3)

ECB:	100061071(GDF3)

EPZ:	103556650(GDF3)

EAI:	106837456(GDF3)

MYB:	102246572(GDF3)

MYD:	102753410(GDF3)

MMYO:

118649552(GDF3)

MLF:	102440764(GDF3)

MDT:	132226019(GDF3)

MYUM:

139005690(GDF3)

PKL:	118728554(GDF3)

EFUS:

103285072(GDF3)

POTS:

308244638(GDF3)

MNA:	107544022(GDF3)

DRO:	112321618(GDF3)

SHON:

119002279(GDF3)

AJM:	119065716(GDF3)

PDIC:

114513581(GDF3)

PHAS:

123819406(GDF3)

MMF:	118624545(GDF3)

PPAM:

129084758(GDF3)

HAI:	109372746(GDF3)

RFQ:	117029191(GDF3)

RHII:

308502154(GDF3)

PALE:

102879662(GDF3)

PGIG:

120611749(GDF3)

PVP:	105295920(GDF3)

RAY:	107501655(GDF3)

MJV:	108383849(GDF3)

TOD:	119248369(GDF3)

SARA:

101553430(GDF3)

SFUM:

130042533(GDF3)

SETR:

126006971(GDF3)

LAV:	100656112(GDF3)

TMU:

101347960

ETF:	101650420(GDF3)

DNM:	101413306(GDF3)

MDO:	100013947(GDF3)

GAS:	123250379(GDF3)

SHR:	100932896(GDF3)

AFZ:

127538665

PCW:	110213870(GDF3)

TVP:	118850018(GDF3)

PBRV:

138175599(GDF3)

MLAO:

141494239(GDF3)

TACU:

119921696 119928629

XLA:	394305(gdf3.S)

XTR:	493288(gdf3)

NPR:

108796579

RTEM:

120924940

ACAT:

141101890

PADS:

140327403 140327714 140327715

BBUF:

120990909

BGAR:

122927406

DTC:

141058898

PWL:	138268139(GDF1)

MUO:	115480271(GDF1)

DRE:	30125(gdf3)

SRX:	107737894 107740853

SANH:

107663137

SGH:

107552892

CCAR:

109069306

CAUA:

113117754(gdf3)

CGIB:

127975959

PTET:

122334374(gdf3)

LROH:

127179380(gdf3)

GRF:	141295939(gdf3)

OMC:	131523391(gdf3)

RKG:	130075789(gdf3)

MAMB:

125269302(gdf3)

CIDE:

127498101

CERY:

137006972(gdf3)

MASI:

127410726 127455232

TROS:

130560567(gdf3)

TDW:	130437070(gdf3)

MANU:

129417709(gdf3)

PDAB:

135736766(gdf3)

IPU:

108270436

IFU:	128612895(gdf3)

PHYP:

113538941(gdf3)

SMEO:

124390174(gdf3)

TFD:	113659798(gdf3)

TVC:	132852102(gdf3)

CGAR:

128536087(gdf3)

NGRA:

132893944(gdf3)

TRN:	134325714 134325715 134325716 134325719 134325720

AMEX:

103043529(gdf3)

CMAO:

118823802(gdf3)

EEE:	113572693(gdf3)

CHAR:

105909473(gdf3)

SPIL:

134067491(gdf3)

ASAD:

121693418(gdf3)

TRU:	101069811(gdf3)

TFS:	130534503(gdf3)

TNG:	GSTEN00010056G001

NCC:	104947007(gdf3)

TBEN:

117480999(gdf3)

CGOB:

115026210(gdf3)

PGEO:

117466934(gdf3)

GACU:

117544421(gdf3)

EMAC:

134866963(gdf3)

ELY:	117251658(gdf3)

EFO:	125899419(gdf3)

PLEP:

121949169 121949369

SLUC:

116036045(gdf3)

ECRA:

117952374(gdf3)

ESP:	116698015(gdf3)

PFLV:

114564199(gdf3)

GAT:	120833479(gdf3)

PPUG:

119228353(gdf3)

AFB:	129104817(gdf3)

CLUM:

117750805(gdf3)

PSWI:

130202520(gdf3)

CANA:

137783179(gdf3)

CVE:	137891877(gdf3)

MSAM:

119884986 119904413

SCHU:

122885053(gdf3)

EARM:

139292827(gdf3)

CUD:	121522316(gdf3)

SPUL:

138592852(gdf3)

LMIX:

132986624(gdf3)

HTC:	141808512(gdf3)

ALAT:

119026474(gdf3)

ASTR:

137605273(gdf3)

PKLU:

139208852(gdf3)

LCO:	104923597(gdf3)

MZE:	101472614(gdf3)

ONL:	100696395(gdf3)

OAU:	116314805(gdf3)

OLA:	101155973(gdf3)

OML:	112154743(gdf3)

CSAI:

133446280(gdf3)

XMA:

102233502

XCO:

114147746

XHE:

116723210

PRET:

103478697(gdf3)

PFOR:

103134793(gdf3)

PLAI:

106955173(gdf3)

PMEI:

106926249(gdf3)

GAF:	122840440(gdf3)

PPRL:

129361341(gdf3)

CVG:

107097387

CTUL:

119791403(gdf3)

GMU:	124871683(gdf3)

NFU:	107389681(gdf3)

KMR:	108238824(gdf3)

ALIM:

106511345(gdf3)

NWH:	119419767(gdf3)

LTU:	140319914(gdf3)

MCEP:

125017755(gdf3)

AOCE:

111565777(gdf3)

EJA:

138201148

BFRE:

138631858

LCF:

108901294

CSEM:

103391908(gdf3)

POV:	109640879(gdf3)

SSEN:

122761181(gdf3)

SSOE:

131453423(gdf3)

HHIP:

117755287(gdf3)

HSP:	118119681(gdf3)

PPLT:

128456225(gdf3)

SMAU:

118282782(gdf3)

SDU:	111218731(gdf3)

SLAL:

111673162(gdf3)

XGL:	120801045(gdf3)

HCQ:	109530569(gdf3)

SSCV:

125974120(gdf3)

SBIA:

133512731(gdf3)

PEE:	133410586(gdf3)

PTAO:

133487089(gdf3)

BPEC:

110162139(gdf3)

ENY:	140359104(gdf3)

MALB:

109972454(gdf3)

BSPL:

114847821(gdf3)

SJO:	128368104(gdf3)

SSCO:

133993321(gdf3)

TTY:	137192157(gdf3)

GMH:	115532729(gdf3)

ZFA:	307244384(gdf3)

SASA:

106582479(gdf3)

STRU:

115155464(gdf3)

OTW:	112235658(gdf3)

OMY:	110501935 118943614

OGO:	124031301(gdf3)

ONE:	115122000(gdf3)

OKI:	109870720(gdf3)

OKE:	118386415(gdf3)

OMM:	135546892(gdf3)

OCLA:

139380617

SALP:

112070753(gdf3)

SNH:	120063658(gdf3)

SFON:

129816730

CCLU:

121555093(gdf3)

ELS:	105029802(gdf3)

OEP:	134017130(gdf3)

SFM:	108938322(gdf3)

PKI:

111857993

AANG:

118208941(gdf3)

AROT:

135252624(gdf3)

CCOG:

133140195(gdf3)

LOC:	102682956(gdf3)

PSPA:

121317662(gdf3)

ARUT:

117411244(gdf3)

PSEX:

120516892(gdf3)

LCM:	102348985(GDF3)

CMK:	103186439(gdf3)

CPUN:

140485953

HOC:	132820888 132820890

LERI:

129702755(gdf3)

HAKA:

140727984(gdf3)

PMRN:

116947068

LRJ:	133361773 133361854

BFO:

BBEL:

SCLV:

APLC:

ARUN:

AAMU:

PFLL:

HRF:

YBA:

LAK:

LLON:

SPIS:

XEN:

Reference

PMID:8429021

Authors

McPherron AC, Lee SJ

Title

GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines.

Journal

J Biol Chem 268:3444-9 (1993)

Sequence

[mmu:14562]

LinkDB

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