KEGG ORTHOLOGY: K26734

ORTHOLOGY: K26734

Entry

K26734                      KO

Symbol

MCC

Name

colorectal mutant cancer protein

Pathway

map04310

Wnt signaling pathway

Disease

H00020

Colorectal cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K26734  MCC; colorectal mutant cancer protein

Genes

HSA:

4163(MCC)

PTR:	462002(MCC)

PPS:	100991342(MCC)

GGO:	101142124(MCC)

PON:	100171411(MCC)

PPYG:

129036981(MCC)

NLE:	100588679(MCC)

HMH:	116470929(MCC)

SSYN:

129492919(MCC)

MCC:	694270(MCC)

MCF:	102133571(MCC)

MTHB:

126956219

MNI:	105499974(MCC)

CSAB:

103244347(MCC)

CATY:

105590685(MCC)

PANU:

101018449(MCC)

TGE:	112625926(MCC)

MLEU:

105529031(MCC)

RRO:	104672111(MCC)

RBB:

108512897

TFN:	117064810(MCC)

PTEH:

111530473(MCC)

CANG:

105527353(MCC)

CJC:	100414475(MCC)

SBQ:

101046980

CIMI:

108303372(MCC)

ANAN:

105729390(MCC)

CSYR:

103258984(MCC)

MMUR:

105870851(MCC)

LCAT:

123648445(MCC)

ERUF:

138398344(MCC)

PCOQ:

105822521(MCC)

OGA:	100949017(MCC)

MMU:	328949(Mcc)

MCAL:

110284496(Mcc)

MPAH:

110333031(Mcc)

RNO:	307449(Mcc)

MCOC:

116087120(Mcc)

ANU:	117720196(Mcc)

ASYL:

127664056(Mcc)

MUN:	110562729(Mcc)

CGE:	100773341(Mcc)

MAUA:

101836275(Mcc)

PROB:

127234199(Mcc)

PLEU:

114701614(Mcc)

PMAV:

102919990(Mcc)

MORG:

121442232 121453512(Mcc)

MFOT:

126505995

AAMP:

119814543(Mcc)

CNL:	130886612(Mcc)

NGI:	103727405(Mcc)

HGL:	101696544(Mcc)

CPOC:

100733895(Mcc)

CCAN:

109685716

DORD:

105985457(Mcc)

DSP:	122100922(Mcc)

DMER:

138803593 138804468

PLOP:

125342207(Mcc)

NCAR:

124987442

MMMA:

107144639(Mcc)

ITI:	101977309(Mcc)

OCU:

100354734

OPI:	101527060(MCC)

OCZ:	121151637(MCC)

TUP:	102490850(MCC)

GVR:	103586848(MCC)

CFA:	611208(MCC)

CLUD:

112651959(MCC)

VVP:	112925315(MCC)

VLG:	121486948(MCC)

NPO:	129509519(MCC)

AML:	100473268(MCC)

UMR:	103675799(MCC)

UAH:	113254984(MCC)

UAR:	123779322(MCC)

ELK:

111148328

LLV:

125100596

MPUF:

101678701(MCC)

MNP:	132028854(MCC)

MLK:	131832536(MCC)

NVS:	122916691(MCC)

ORO:	101374014(MCC)

EJU:	114208744(MCC)

ZCA:	113928912(MCC)

MLX:	118017485(MCC)

NSU:	110590609(MCC)

LWW:

102746262

FCA:	101097788(MCC)

PYU:	121011853(MCC)

PCOO:

112861099(MCC)

PBG:	122487843(MCC)

PVIV:

125176955(MCC)

LRUF:

124519847

LGF:	123581090(MCC)

AJU:

106973159

PTG:	102971707(MCC)

PPAD:

109267594(MCC)

PUC:

125934376

PLEZ:

122224040(MCC)

HHV:	120236766(MCC)

BTA:	616704(MCC)

BOM:	102273934(MCC)

BIU:	109564161(MCC)

BBUB:

102401931(MCC)

BKE:	129620779(MCC)

BBIS:

104994708(MCC)

CHX:	102183148(MCC)

OAS:	101121522(MCC)

BTAX:

128054240(MCC)

CSUM:

138072918(MCC)

ODA:	120852630 120861032

CCAD:

122442937(MCC)

MREE:

136171868(MCC)

OVR:	110142065(MCC)

MBEZ:

129562437(MCC)

SSC:	100515712(MCC)

CFR:	102524393(MCC)

CBAI:

105082029(MCC)

CDK:	105095386(MCC)

VPC:	102538584(MCC)

BACU:

102999509(MCC)

BMUS:

118891842(MCC)

LVE:	103081661(MCC)

OOR:	101274417(MCC)

LALB:

132516986(MCC)

GMF:	115860249(MCC)

DDP:	132423371(MCC)

DLE:	111183687(MCC)

PCAD:

102997032(MCC)

PSIU:

116751217(MCC)

PPHC:

136120524(MCC)

NASI:

112398690(MCC)

ECB:	100064404(MCC)

EPZ:	103558657(MCC)

EAI:	106832198(MCC)

MYB:	102248933(MCC)

MYD:	102775194(MCC)

MMYO:

118655760(MCC)

MLF:

102432247

MDT:

132233355

MYUM:

139008811(MCC)

PKL:	118703764(MCC)

EFUS:

103288717(MCC)

MNA:	107546492(MCC)

DRO:	112307198(MCC)

SHON:

118977349(MCC)

AJM:	119065101(MCC)

PDIC:

114493666(MCC)

PHAS:

123818019(MCC)

MMF:	118642392(MCC)

PPAM:

129083905(MCC)

HAI:	109391526(MCC)

RFQ:	117024990(MCC)

PALE:

102897926(MCC)

PGIG:

120590828(MCC)

PVP:	105295482(MCC)

RAY:	107512085(MCC)

MJV:	108408631(MCC)

TOD:	119260373(MCC)

SARA:

101557454(MCC)

SFUM:

130046131(MCC)

SETR:

126011908(MCC)

LAV:	100673049(MCC)

TMU:

101361432

ETF:	101660245(MCC)

DNM:	101414535(MCC)

MDO:	100015680(MCC)

GAS:	123251000(MCC)

SHR:	100927570(MCC)

AFZ:

127538402

PCW:	110203564(MCC)

TVP:	118830742(MCC)

PBRV:

138160572(MCC)

MLAO:

141499947(MCC)

OAA:	103170396(MCC)

TACU:

119947811(MCC)

GGA:	415603(MCC)

PCOC:

116239718(MCC)

CJO:	107306336(MCC)

TPAI:

128089487(MCC)

LMUT:

125686855(MCC)

NMEL:

110389918(MCC)

APLA:

101802258(MCC)

AACU:

137848497(MCC)

ACYG:

106046534(MCC)

CATA:

118255968(MCC)

AFUL:

116500459(MCC)

TGU:	100220174(MCC)

LSR:	110467604(MCC)

SCAN:

103824108(MCC)

PMOA:

120500896(MCC)

OTC:	121333118(MCC)

PRUF:

121355544(MCC)

ATRC:

139605109(MCC)

GFR:	102040744(MCC)

FAB:	101818280(MCC)

OMA:	130264935(MCC)

PHI:	102100022(MCC)

PMAJ:

107216209(MCC)

CCAE:

111941775(MCC)

CCW:	104684170(MCC)

CBRC:

103611217

ACOE:

138099661(USHBP1) 138103962(MCC)

ETL:	114054661(MCC)

ZAB:	102071262(MCC)

ZLE:	135459436(MCC)

ACHL:

103803487(MCC)

SVG:	106862818(MCC)

MMEA:

130574326(MCC)

HRT:	120765178(MCC)

SATI:

136374002(MCC)

CFAI:

136288522

CCIC:

134056387(MCC)

FPG:	101913963(MCC)

FCH:	102051375(MCC)

CCRI:

104168176(MCC)

NNT:

104403407

SHAB:

115600579(MCC)

ACUN:

113489553(MCC)

SURA:

141938318(MCC)

TALA:

104366635(MCC)

ACHC:

115337497(MCC)

HALD:

104322836(MCC)

HLE:	104829308(MCC)

AGEN:

126035832

HHAR:

128137768(MCC)

BBUT:

142027053(MCC)

GCL:

127027695

CSTI:

104559601(MCC)

LDI:

104353079

MNB:	103774832(MCC)

DPUB:

104296271(MCC)

PPUS:

135173323(MCC)

AVIT:

104275544(MCC)

BRHI:

104492609(MCC)

EGZ:	104135072(MCC)

NNI:	104016353(MCC)

PCRI:

104031041(MCC)

PCAO:

104041508(MCC)

PARX:

142050552(MCC)

PADL:

103914453(MCC)

AFOR:

103903045

FGA:	104080454(MCC)

CBOR:

142075407(MCC)

GSTE:

104250427(MCC)

CBOY:

140651180(MCC)

MAME:

142402756(MCC)

CLV:	102093570(MCC)

CNIC:

136002511(MCC)

MUI:

104541140

PGUU:

104458810(MCC)

PLET:

104620019(MCC)

EHS:	104513627(MCC)

CMAC:

104486522(MCC)

CUCA:

104060229(MCC)

TEO:	104382941(MCC)

BREG:

104629044(MCC)

GAME:

129199288(MCC)

OHA:	104337844(MCC)

ACAR:

104531073(MCC)

CPEA:

104389762(MCC)

CVF:	104294225(MCC)

RTD:	128902771(MCC)

CRID:

134509004(MCC)

LMIC:

141735839(MCC)

NARQ:

141477035(MCC)

AROW:

112963137(MCC)

NPD:	112958902(MCC)

TGT:	104571521(MCC)

DNE:	112995225(MCC)

SCAM:

104150980(MCC)

ASN:	102377895(MCC)

AMJ:	102568335(MCC)

CPOO:

109308181(MCC)

GGN:	109297489(MCC)

PSS:	102443862(MCC)

CIZ:	142002416(USHBP1) 142013608(MCC)

CMY:	102942291(MCC)

CCAY:

125636536(MCC)

LKP:	140911503(MCC)

NDS:	141987540(MCC)

DCC:	119855844(MCC)

CPIC:

101948898(MCC)

TST:	117878683(MCC)

CABI:

116817824(MCC)

MRV:	120407955(MCC)

ACS:	100562164(mcc)

ASAO:

132767205(MCC)

PVT:	110072035(MCC)

SUND:

121921154(MCC)

PBI:

103060709

PMUR:

107293249(MCC)

CTIG:

120318586(MCC)

TSR:	106540729(MCC)

PGUT:

117674649(MCC)

PCAE:

139313239(MCC)

APRI:

131189737(MCC)

PTEX:

113449075(MCC)

NSS:	113415754(MCC)

VKO:	123031286(MCC)

PMUA:

114606870(MCC)

PRAF:

128423470(MCC)

ZVI:	118076792(MCC)

HCG:	128344623(MCC)

GJA:	107116679(MCC)

STOW:

125436398(MCC)

EMC:	129335038(MCC)

XLA:	108707212(mcc.S) 108717348

XTR:	100216150(mcc)

NPR:	108791893(MCC)

RTEM:

120931789(MCC)

ACAT:

141137956(MCC)

PADS:

140334015(MCC)

BBUF:

120992578(MCC)

BGAR:

122924636(MCC)

DTC:	141054261(MCC)

HSQ:	130288720(MCC)

PWL:	138286190(MCC)

MUO:	115463197(MCC)

GSH:	117352576(MCC)

DRE:	100537329(mcc)

SRX:

107720969

SANH:

107701845(mcc)

SGH:	107563422(mcc)

CCAR:

109057081 109070932(mcc)

CAUA:

113070143 113070821

CGIB:

127958218 128014913

PTET:

122345127(mcc)

LROH:

127165520(mcc)

GRF:	141334927(mcc)

OMC:	131540703(mcc)

PPRM:

120471632(mcc)

RKG:	130101109(mcc)

MAMB:

125266217(mcc)

CIDE:

127512727 127513165

CERY:

137034414(mcc)

MASI:

127423252 127433207

TROS:

130545279(mcc)

TDW:	130419604(mcc)

MANU:

129439551(mcc)

PDAB:

135732774(mcc)

IPU:

108260031

IFU:	128603534(mcc)

PHYP:

113531552(mcc)

TFD:	113656675(mcc)

TVC:	132840962(mcc)

CGAR:

128512291(mcc)

TRN:	134303629(mcc)

AMEX:

103047184(mcc)

CMAO:

118814803(mcc)

EEE:	113583630(mcc)

CHAR:

105902523(mcc)

SPIL:

134101520(mcc)

ASAD:

121680569(mcc)

SASA:

106563245 106565572

STRU:

115159519 115204121

OTW:	112219349 112233454

OMY:	110509842 110523629

OGO:	124006804 124048917

ONE:	115101207 115123324

OKI:	109868480 109874406

OKE:	118384859 118387570

OMM:	135517938 135544425

OCLA:

139388696 139408668

SALP:

111961569

SNH:	120021001 120025541

SFON:

129818490 129864094

CCLU:

121541709 121582465

ELS:	105015096(mcc)

OEP:	134034107(mcc)

SFM:	108923557(mcc)

PKI:	111843796(mcc)

AANG:

118213186(mcc)

AROT:

135239364(mcc)

CCOG:

133142438(mcc)

LOC:	102682892(mcc)

PSPA:

121302827 121315149

ARUT:

117409395 117424174

PSEX:

120532674(mcc)

LCM:	102356214(MCC)

CMK:	103181142(mcc)

RTP:	109929958(mcc)

CPLA:

122560271(mcc)

CPUN:

140485581(mcc) 140494799(ushbp1)

HOC:	132823527(mcc) 132828938

SCAU:

119953110 119970453

STOZ:

140429449(mcc)

HAKA:

140739890 140739925(mcc)

PMRN:

116953534

LRJ:	133355027 133355210

BFO:

BBEL:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG34404(CG34404)

DER:

6553098

DSE:

6606264

DSI:	Dsimw501_GD20354(Dsim_GD20354)

DYA:	Dyak_GE26381

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI24310

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:	119606688 119611778

CVJ:

GFS:

ECOE:

CLON:

HIS:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

TAME:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

RFG:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

CFEL:

CCRN:

API:

DNX:

RMD:

BTAB:

NLU:

LDA:

MQU:

PHU:	Phum_PHUM359120

FOC:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_309841

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

HAZT:

OOT:

EAF:

LSM:

TCF:	131882444 131887278

DSV:

DALB:

RSAN:

RMP:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

106463516 106468931 106469040

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

RES:

AQU:

Reference

PMID:1848370

Authors

Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A, et al.

Title

Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers.

Journal

Science 251:1366-70 (1991)
DOI:10.1126/science.1848370

Sequence

[hsa:4163]

LinkDB

DBGET integrated database retrieval system