Homo sapiens (human): 4163
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Entry
4163 CDS
T01001
Symbol
MCC, MCC1
Name
(RefSeq) MCC regulator of WNT signaling pathway
KO
K26734
colorectal mutant cancer protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
Disease
H00020
Colorectal cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
4163 (MCC)
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Gene cluster
GFIT
Motif
Pfam:
USHBP1_PDZ-bd
Mod_r
SHE3
Motif
Other DBs
NCBI-GeneID:
4163
NCBI-ProteinID:
NP_002378
OMIM:
159350
HGNC:
6935
Ensembl:
ENSG00000171444
UniProt:
P23508
Structure
PDB
PDBj
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All DBs
Position
5:complement(113022106..113488453)
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AA seq
829 aa
AA seq
DB search
MNSGVAMKYGNDSSAELSELHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQ
SHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQS
QHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSS
CSLSVAEVDKHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLRE
ENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTS
TNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSV
AEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTIT
LEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAA
GVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAVAGCSVQPWES
LSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSY
DVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAY
LVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAELRTTCSENELA
AEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAK
KKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL
NT seq
2490 nt
NT seq
+upstream
nt +downstream
nt
atgaattccggagttgccatgaaatatggaaacgactcctcggccgagctgagtgagctc
cattcagcagccctggcatcactaaagggagatatagtggaacttaataaacgtctccag
caaacagagagggaacgggaccttctggaaaagaaattggccaaggcacagtgcgagcag
tcccacctcatgagagagcatgaggatgtccaggagcgaacgacacttcgctatgaggaa
cgcatcacagagctccacagcgtcattgcggagctcaacaagaagatagaccgtctgcaa
ggcaccaccatcagggaggaagatgagtactcagaactgcgatcagaactcagccagagc
caacacgaggtcaacgaggactctcgaagcatggaccaagaccagacctctgtctctatc
cccgaaaaccagtctaccatggttactgctgacatggacaactgcagtgacctgaactca
gaactgcagagggtgctgacagggctggagaatgttgtctgcggcaggaagaagagcagc
tgcagcctctccgtggccgaggtggacaagcacattgagcagctcaccacagccagcgag
cactgtgacctggctattaagacagtcgaggagattgagggggtgcttggccgggacctg
tatcccaacctggctgaagagaggtctcggtgggagaaggagctggctgggctgagggaa
gagaatgagagcctgactgccatgctgtgcagcaaagaggaagaactgaaccggactaag
gccaccatgaatgccatccgggaagagcgggaccggctccggaggagggtcagagagctt
caaactcgactacagagcgtgcaggccacaggtccctccagccctggccgcctcacttcc
accaaccgcccgattaaccccagcactggggagctgagcacaagcagcagcagcaatgac
attcccatcgccaagattgctgagagggtgaagctatcaaagacaaggtccgaatcgtca
tcatctgatcggccagtcctgggctcagaaatcagtagcataggggtatccagcagtgtg
gctgaacacctggcccactcacttcaggactgctccaatatccaagagattttccaaaca
ctctactcacacggatctgccatctcagaaagcaagattagagagtttgaggtggaaaca
gaacggctgaatagccggattgagcacctcaaatcccaaaatgacctcctgaccataacc
ttggaggaatgtaaaagcaatgccgagaggatgagcatgctggtgggaaaatacgaatcc
aatgccacagcgctgaggctggccttgcagtacagcgagcagtgcatcgaagcctacgaa
ctcctcctggcgctggcagagagtgagcagagcctcatcctggggcagttccgagcggcg
ggcgtggggtcctcccctggagaccagtcgggggatgaaaacatcactcagatgctcaag
cgagctcatgactgccggaagacagctgagaacgctgccaaggccctgctcatgaagctg
gacggcagctgtgggggagcctttgccgtggccggctgcagcgtgcagccctgggagagc
ctttcctccaacagccacaccagcacaaccagctccacagccagtagttgcgacaccgag
ttcactaaagaagacgagcagaggctgaaggattatatccagcagctcaagaatgacagg
gctgcggtcaagctgaccatgctggagctggaaagcatccacatcgatcctctcagctat
gacgtcaagcctcggggagacagccagaggctggatctggaaaacgcagtgcttatgcag
gagctcatggccatgaaggaggagatggccgagttgaaggcccagctctacctactggag
aaagagaagaaggccctggagctgaagctgagcacgcgggaggcccaggagcaggcctac
ctggtgcacattgagcacctgaagtccgaggtggaggagcagaaggagcagcggatgcga
tccctcagctccaccagcagcggcagcaaagacaaacctggcaaggagtgtgctgatgct
gcctccccagctctgtccctagccgaactcaggacaacgtgcagcgagaatgagctggct
gcggagttcaccaacgccattcgtcgagaaaagaagttgaaggccagagttcaagagctg
gtgagtgccttggagagactcaccaagagcagtgaaatccgacatcagcaatctgcagag
ttcgtgaatgatctaaagcgggccaacagcaacctggtggctgcctatgagaaagcaaag
aaaaagcatcaaaacaaactgaagaagttagagtcgcagatgatggccatggtggagaga
catgagacccaagtgaggatgctcaagcaaagaatagctctgctagaggaggagaactcc
aggccacacaccaatgaaacttcgctttaa
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