KEGG ORTHOLOGY: K28020

ORTHOLOGY: K28020

Entry

K28020                      KO

Symbol

FERRY3

Name

Ferry endosomal RAB5 effector complex subunit 3

Disease

H00768

Autosomal recessive intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K28020  FERRY3; Ferry endosomal RAB5 effector complex subunit 3
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Rab GTPases and associated proteins
   FERRY complex
    K28020  FERRY3; Ferry endosomal RAB5 effector complex subunit 3

Genes

HSA:	57102(FERRY3)

PTR:	451764(FERRY3)

PPS:	100989147(FERRY3)

GGO:	101144037(FERRY3)

PON:	100172023(FERRY3)

PPYG:

129010459(FERRY3)

NLE:	100606027(C23H12orf4)

HMH:	116472554(CUNH12orf4)

SSYN:

129483512(FERRY3)

MCC:	710836(C11H12orf4)

MCF:	101866927(FERRY3)

MTHB:

126931737(C11H12orf4)

MNI:	105484153(CUNH12orf4)

CSAB:

103218417(C11H12orf4)

CATY:

105582994

PANU:

101006109(C9H12orf4)

TGE:	112635398(C11H12orf4)

MLEU:

105551126

RRO:	104658984(C10H12orf4)

RBB:	108536502(CUNH12orf4)

TFN:	117090669(CUNH12orf4)

PTEH:

111535832(C10H12orf4)

CANG:

105503935

CJC:	100390896(C9H12orf4)

SBQ:

101047867

CIMI:

108316321(CUNH12orf4)

ANAN:

105719694(FERRY3)

CSYR:

103250106(CUNH12orf4)

MMUR:

105881451(C7H12orf4)

LCAT:

123640147(C6H12orf4)

OGA:	100960930(CUNH12orf4)

MMU:	28040(D6Wsu163e)

MCAL:

110296311(C6H12orf4)

MPAH:

110316913(C2H12orf4)

RNO:	297607(Ferry3)

MCOC:

116099626(CUNH12orf4)

ANU:	117715287(C9H12orf4)

ASYL:

127679233(C2H12orf4)

MUN:	110545552(C5H12orf4)

CGE:	100772405(C8H12orf4)

MAUA:

101842558(CUNH12orf4)

PROB:

127212857(CUNH12orf4)

PLEU:

114701442(C3H12orf4)

MORG:

121442577(CUNH12orf4)

MFOT:

126488488(CUNH12orf4)

AAMP:

119807711(C2H12orf4)

NGI:	103727542(CUNH12orf4)

HGL:

101723232

CPOC:

100731160(CUNH12orf4)

CCAN:

109697167(CUNH12orf4)

DORD:

105991005

DSP:	122102112(CUNH12orf4)

DMER:

138816332(Ferry3)

PLOP:

125342897(C27H12orf4)

NCAR:

124983974

MMMA:

107154985(CUNH12orf4)

ITI:	101968164(CUNH12orf4)

OCU:	100348146(C8H12orf4)

OPI:	101528827(C8AH12orf4)

OCZ:	121155436(CUNH12orf4)

TUP:

102477615

GVR:

103602660

CFA:	477721(C27H12orf4)

CLUD:

112669054(C27H12orf4)

VVP:	112917376(CUNH12orf4) 112925704

VLG:	121480234(C21H12orf4)

NPO:	129503484(CUNH12orf4)

AML:	100470518(C16H12orf4)

UMR:	103675749(CUNH12orf4)

UAH:	113257999(CUNH12orf4)

UAR:	123781577(CUNH12orf4)

ELK:

111159765

LLV:

125107105

MPUF:

101682889

MNP:	132019948(C6H12orf4)

MLK:	131838417(C8H12orf4)

NVS:	122891478(C12H12orf4)

ORO:

101364366

EJU:	114222453(CUNH12orf4)

ZCA:	113923026(C9H12orf4)

MLX:	118025763(CUNH12orf4)

NSU:	110580876(C5H12orf4)

LWW:	102742256(CUNH12orf4)

FCA:	101091952(CB4H12orf4)

PYU:	121022099(CUNH12orf4)

PCOO:

112867390(CUNH12orf4)

PBG:	122473914(CB4H12orf4)

PVIV:

125170422(CB4H12orf4)

LRUF:

124502093

LGF:	123590078(CB4H12orf4)

AJU:	106965377(C8H12orf4)

PTG:

102969384

PPAD:

109276196(CUNH12orf4)

PUC:	125918742(CB4H12orf4)

PLEZ:

122224126(CB4H12orf4)

HHV:	120247738(CUNH12orf4)

BTA:	515243(C5H12orf4)

BOM:	102271718(FERRY3)

BIU:	109559739(C5H12orf4)

BBUB:

102408703(C4H12orf4)

BBIS:

104992214

CHX:	102180111(C5H12orf4)

OAS:	101116469(C3H12orf4)

BTAX:

128048336(C5H12orf4)

CSUM:

138078277(FERRY3)

ODA:	120857883(CUNH12orf4)

CCAD:

122423443(C21H12orf4)

MREE:

136173170(FERRY3)

OVR:	110122325(FERRY3)

MBEZ:

129536345(CUNH12orf4)

SSC:	100153309(C5H12orf4)

CFR:	102506346(C34H12orf4)

CBAI:

105076528

CDK:	105091324(C34H12orf4)

VPC:	102544697(C34H12orf4)

BACU:

103002162

BMUS:

118902886(C10H12orf4)

LVE:

103077154

OOR:	101275464(C11H12orf4)

LALB:

132530068(C11H12orf4)

GMF:	115841065(FERRY3)

DDP:	132433427(FERRY3)

DLE:	111176640(CUNH12orf4)

PCAD:

102984543(C6H12orf4)

PSIU:

116761066(C10H12orf4)

PPHC:

136130976(FERRY3)

NASI:

112391926(CUNH12orf4)

ECB:	100051294(C6H12orf4)

EPZ:	103557836(FERRY3)

EAI:	106831497(C22H12orf4)

MYB:

102255424

MYD:

102754581

MMYO:

118651222(CUNH12orf4)

MLF:	102431601(CUNH12orf4)

MDT:	132228042(C2H12orf4)

MYUM:

139006833(FERRY3)

PKL:	118729876(CUNH12orf4)

EFUS:

103288036(C7H12orf4)

MNA:

107538916

DRO:	112313006(CUNH12orf4)

SHON:

118999950(CUNH12orf4)

AJM:	119054866(CUNH12orf4)

PDIC:

114513244(C2H12orf4)

PHAS:

123813560(CUNH12orf4)

MMF:	118624484(CUNH12orf4)

PPAM:

129074233(CUNH12orf4)

HAI:	109392472(CUNH12orf4)

RFQ:	117029317(C10H12orf4)

PALE:

102891892(CUNH12orf4)

PGIG:

120607303(CUNH12orf4)

PVP:	105293258(CUNH12orf4)

RAY:	107513444(CUNH12orf4)

MJV:	108391345(CUNH12orf4)

TOD:	119247813(CUNH12orf4)

SARA:

101539160

SFUM:

130017890(CUNH12orf4)

SETR:

126006946(C4H12orf4)

LAV:	100669190(CUNH12orf4)

TMU:

101352552

ETF:	101657687(CUNH12orf4)

DNM:	101445166(CUNH12orf4)

MDO:	100016018(C8H12orf4)

GAS:	123248744(C5H12orf4)

SHR:	100914321(C5H12orf4)

AFZ:	127564143(C5H12orf4)

PCW:	110218649(CUNH12orf4)

TVP:	118851923(C5H12orf4)

PBRV:

138171925(FERRY3)

MLAO:

141493372(FERRY3)

OAA:	100090630(CX4H12orf4)

TACU:

119946560(C27H12orf4)

GGA:	419041(C1H12ORF4)

PCOC:

116237212(CUNH12orf4)

MGP:	100548684(C1H12orf4)

CJO:	107317974(C1H12orf4)

TPAI:

128084466(CUNH12orf4)

LMUT:

125688186(C1H12orf4)

NMEL:

110390644(CUNH12orf4)

APLA:

101803213(C1H12orf4)

ACYG:

106046304(FERRY3)

CATA:

118247615(C1H12orf4)

AFUL:

116489339(C1H12orf4)

TGU:	100232702(C1AH12orf4)

LSR:	110479028(FERRY3)

SCAN:

103819600(CUNH12orf4)

PMOA:

120501529(CUNH12orf4)

OTC:	121332875(CUNH12orf4)

PRUF:

121364335(CUNH12orf4)

ATRC:

139587862(FERRY3)

GFR:

102035018

FAB:	101817388(C1AH12orf4)

OMA:	130267051(C1AH12orf4)

PHI:

102113831

PMAJ:

107204931(C1AH12orf4)

CCAE:

111929889(C1H12orf4)

CCW:	104696176(C1AH12orf4)

CBRC:

103623346(CUNH12orf4)

ACOE:

138104233(FERRY3)

ETL:	114067082(CUNH12orf4)

ZAB:	102060916(CUNH12orf4)

ZLE:	135441429(FERRY3)

ACHL:

103803015

SVG:

106849374

MMEA:

130586348(CUNH12orf4)

HRT:	120751902(C4H12orf4)

SATI:

136361632(FERRY3)

CCIC:

134042991(FERRY3)

FPG:

101919822

FCH:	102054076(CUNH12orf4)

CCRI:

104159747

NNT:

104409259

SHAB:

115605097(C3H12orf4)

ACUN:

113491349(C1H12orf4)

TALA:

104365141(CUNH12orf4)

ACHC:

115352391(C17H12orf4)

HALD:

104322494

HLE:

104836647

AGEN:

126047848(C18H12orf4)

HHAR:

128142607(C6H12orf4)

GCL:	127026465(C1H12orf4)

CSTI:

LDI:

MNB:

DPUB:

PPUS:

135174795(FERRY3)

AVIT:

104280435

BRHI:

104489308

EGZ:	104124207(CUNH12orf4)

NNI:

PCRI:

PCAO:

PADL:

AFOR:

103906577(CUNH12orf4)

FGA:

104073541

CBOR:

142088035(FERRY3)

GSTE:

104256605

CBOY:

140658842(FERRY3)

MAME:

142412834(FERRY3)

CLV:	102092348(CUNH12orf4)

CNIC:

135985922(FERRY3)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

104066626(C1H12orf4)

TEO:

104372455

BREG:

104629687

OHA:

104333007

ACAR:

104520790(CUNH12orf4)

CPEA:

104397225

CVF:

104294542

RTD:	128913127(C1H12orf4)

CRID:

134525299(FERRY3)

LMIC:

141744019(FERRY3)

AAM:

106489566

AROW:

112971500(CUNH12orf4)

NPD:	112955048(CUNH12orf4)

TGT:

104574076

DNE:	112986825(CUNH12orf4)

SCAM:

104144400

ASN:	102368214(CUNH12orf4)

AMJ:	102569161(CUNH12orf4)

CPOO:

109316270(CUNH12orf4)

GGN:	109296573(CUNH12orf4)

PSS:	102461644(CUNH12orf4)

CIZ:	142017739(FERRY3)

CMY:	102937093(C1H12orf4)

CCAY:

125623761(C1H12orf4)

DCC:	119851958(C1H12orf4)

CPIC:

101940782(C1H12orf4)

TST:	117884584(C1H12orf4)

CABI:

116822114(CUNH12orf4)

MRV:	120405273(C1H12orf4)

ACS:	100563277(c5h12orf4)

ASAO:

132776424(CUNH12orf4)

PVT:	110087498(CUNH12orf4)

SUND:

121932048(C5H12orf4)

PBI:	103052774(CUNH12orf4)

PMUR:

107302452(CUNH12orf4)

CTIG:

120298259(CUNH12orf4)

TSR:

106539827

PGUT:

117673859(CUNH12orf4)

PCAE:

139312272(FERRY3)

APRI:

131190244(C2H12orf4)

PTEX:

113451894(CUNH12orf4)

NSS:	113418935(CUNH12orf4)

VKO:	123017017(CUNH12orf4)

PMUA:

114596923(C5H12orf4)

PRAF:

128413586(C5H12orf4)

ZVI:	118096299(LG14H12orf4)

HCG:	128326248(C5H12orf4)

GJA:

107110408

STOW:

125425583(CUNH12orf4)

EMC:	129344234(C16H12orf4)

XLA:	379131(c12orf4.L)

XTR:	493240(c12orf4)

NPR:	108788074(CUNH12orf4)

RTEM:

120932649(C3H12orf4)

ACAT:

141132634(FERRY3)

BBUF:

121007361(C1H12orf4)

BGAR:

122926550(C2H12orf4)

DTC:	141083496(FERRY3)

PWL:	138287717(FERRY3)

MUO:	115477574(C9H12orf4)

GSH:	117363761(C7H12orf4)

DRE:	777745(zgc:154077)

SRX:	107707474 107732788

SANH:

107686672 107700900

SGH:

107573305

CCAR:

109050638 109050644

CAUA:

113043086 113066865 113074223

CGIB:

127946650 128014487(cb25h12orf4)

PTET:

122331243(c25h12orf4)

LROH:

127156476(c25h12orf4)

GRF:	141301604(ferry3)

OMC:	131534908(c25h12orf4)

PPRM:

120459005(cunh12orf4)

RKG:	130085274(cunh12orf4)

MAMB:

125247538(lg15h12orf4)

CIDE:

127507567(c24h12orf4)

CERY:

137014957(ferry3)

MASI:

127437820

TROS:

130551762(lg3h12orf4)

TDW:	130413892(c24h12orf4)

MANU:

129434071(ferry3)

PDAB:

135781317(ferry3)

IPU:	108269243(c8h12orf4)

IFU:	128611707(c8h12orf4)

PHYP:

113546675(cunh12orf4)

SMEO:

124386390(c5h12orf4)

TFD:	113636004(c17h12orf4)

TVC:	132855900(c13h12orf4)

CGAR:

128531272(c10h12orf4)

NGRA:

132890953(c8h12orf4)

TRN:	134319543(ferry3)

AMEX:

103029927(c10h12orf4)

CMAO:

118806680(cunh12orf4)

EEE:	113584989(cunh12orf4)

CHAR:

105895654(c3h12orf4)

SPIL:

134093863(ferry3)

ASAD:

121723252(c11h12orf4)

TRU:	101068380(c9h12orf4)

TFS:	130536417(c13h12orf4)

TNG:	GSTEN00016777G001

LCO:	104922117(cxxih12orf4)

NCC:

104953706

TBEN:

117491830(cunh12orf4)

CGOB:

115010074(c6h12orf4)

PGEO:

117448418

GACU:

117542784(cunh12orf4)

EMAC:

134876917(ferry3)

ELY:	117261673(c11h12orf4)

EFO:	125886783(lg4h12orf4)

PLEP:

121950734(c11h12orf4)

SLUC:

116052996(c7h12orf4)

ECRA:

117948442(c8h12orf4)

PFLV:

114560243(c8h12orf4)

GAT:	120809328(c19h12orf4)

PPUG:

119196317(ferry3)

AFB:	129108265(c19h12orf4)

CLUM:

117732831(c6h12orf4)

PSWI:

130195193(c6h12orf4)

CANA:

137804231(ferry3)

CVE:	137880974(ferry3)

MSAM:

119893974(cunh12orf4)

SCHU:

122874764(lg4h12orf4)

CUD:	121514525(c9h12orf4)

SPUL:

138612864(ferry3)

LMIX:

132973326(c4h12orf4)

HTC:	141795913(ferry3)

ALAT:

119024003(c8h12orf4)

ASTR:

137594024(ferry3)

MZE:	101476100(lg7h12orf4)

ONL:	100697519(lg7h12orf4)

OAU:	116326342(c7h12orf4)

OLA:	101174182(c6h12orf4)

OML:	112152251(lg6h12orf4)

CSAI:

133443946(ferry3)

XMA:	102231550(c2h12orf4)

XCO:	114152324(c2h12orf4)

XHE:	116708518(c2h12orf4)

PRET:

103466816(clg6h12orf4)

PFOR:

103155808

PLAI:

106953389

PMEI:

106933446

GAF:	122835102(lg08h12orf4)

PPRL:

129356224 129360167

CVG:

107084314

CTUL:

119789172(cunh12orf4)

GMU:	124857334(c2h12orf4)

NFU:	107389322(csgr13h12orf4)

KMR:	108237452(lg11h12orf4)

ALIM:

106536829

NWH:	119416192(c10h12orf4)

AOCE:

111572091(c3h12orf4)

EJA:	138205783(ferry3)

BFRE:

138624821(ferry3)

MCEP:

125015388(c10h12orf4)

CSEM:

103379559(c6h12orf4)

POV:	109624345(cunh12orf4)

SSEN:

122761008(cunh12orf4)

SSOE:

131470571(c12h12orf4)

HHIP:

117762776(c6h12orf4)

HSP:	118109160(c5h12orf4)

PPLT:

128444902(c7h12orf4)

SMAU:

118315743(c7h12orf4)

LCF:	108901919(lg10h12orf4)

SDU:	111225177(cunh12orf4)

SLAL:

111666110(cunh12orf4)

XGL:	120793781(c8h12orf4)

HCQ:	109526795(cunh12orf4)

SSCV:

125971293(ferry3)

SBIA:

133502702(ferry3)

PEE:	133402498(ferry3)

PTAO:

133478667(ferry3)

BPEC:

110169583(cunh12orf4)

ENY:	140348697(ferry3)

MALB:

109962530(cunh12orf4)

BSPL:

114857056(c6h12orf4)

SJO:	128359198(c5h12orf4)

SSCO:

133981571(ferry3)

TTY:	137182688(ferry3)

GMH:	115550334(c9h12orf4)

SASA:

106561360 106573194

STRU:

115152233 115197438

OTW:	112218780 112252581

OMY:	110498298 110523466

OGO:	124003118(lg02h12orf4) 124034450

ONE:	115109598 115134048

OKI:	109867798 109889565

OKE:	118401044(c22h12orf4)

OMM:	135509138 135524188

OCLA:

139374366 139407388

SALP:

111952312 111962626

SNH:	120042002 120054104

SFON:

129866802(c12h12orf4)

CCLU:

121532313 121576948

ELS:	105018231(lg19h12orf4)

OEP:	134021673(ferry3)

SFM:	108918624(c21h12orf4)

PKI:	111857724(cunh12orf4)

AANG:

118232343(c7h12orf4)

AROT:

135259042(ferry3)

CCOG:

133135951(c8h12orf4)

LOC:	102696129(clg8h12orf4)

PSPA:

121318074 121320018

ARUT:

117415189 117419555

PSEX:

120533720(c8h12orf4)

LCM:

102353173

CMK:	103185574(cunh12orf4)

RTP:	109921348(c22h12orf4)

CPLA:

122561685(c23h12orf4)

HOC:	132826739(c23h12orf4)

SCAU:

119973370(c11h12orf4)

LERI:

129707746(c22h12orf4)

HAKA:

140738681(ferry3)

PMRN:

116956517(C65H12orf4)

LRJ:	133360380 133360383

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG9986(CG9986)

DER:

6555366

DSE:

6618780

DSI:	Dsimw501_GD21375(Dsim_GD21375)

DYA:	Dyak_GE23792

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI10578

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108354004 108371316

AOQ:

129248509

ALUD:

128854717

TDA:

119685916

MDE:	101891068 131802811

SCAC:

LCQ:

LSQ:

CVJ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ008645

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

DCOR:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208213

BANY:

MJU:

NIQ:

VCD:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

CSTB:

CFUM:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM490690

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

PVM:

PJA:	122244477 122252573

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_C55A6.10(C55A6.10)

CBR:

CBG_23228

CRQ:	GCK72_016785

NAI:	NECAME_04230

BMY:	BM_BM2950(Bm2950)

LOA:	LOAG_11021

TSP:

Tsp_05648

HRO:	HELRODRAFT_111877

LGI:	LOTGIDRAFT_108291

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_163270

SHX:	MS3_00003878

OVI:	T265_07776

EGL:

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114530180 114540527

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_2109

AQU:

100637763

MBR:	MONBRDRAFT_25304

SRE:	PTSG_07125

» show all

Reference

PMID:37267905

Authors

Schuhmacher JS, Tom Dieck S, Christoforidis S, Landerer C, Davila Gallesio J, Hersemann L, Seifert S, Schafer R, Giner A, Toth-Petroczy A, Kalaidzidis Y, Bohnsack KE, Bohnsack MT, Schuman EM, Zerial M

Title

The Rab5 effector FERRY links early endosomes with mRNA localization.

Journal

Mol Cell 83:1839-1855.e13 (2023)
DOI:10.1016/j.molcel.2023.05.012

Sequence

[hsa:57102]

LinkDB

DBGET integrated database retrieval system