KEGG   MODULE: M00015
Entry
M00015            Pathway   Module                                 
Name
Proline biosynthesis, glutamate => proline
Definition
((K00931 K00147),K12657) K00286
Diagram
M00015

Orthology
K00931  
glutamate 5-kinase [EC:2.7.2.11] [RN:R00239]
K00147  
glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] [RN:R03313]
K12657  
delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41] [RN:R00239 R03313]
K00286  
pyrroline-5-carboxylate reductase [EC:1.5.1.2] [RN:R01251]
Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
map00330  Arginine and proline metabolism
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Reaction
R00239  
R03313  
R00667  
R03314  
R01251  
Compound
C00025  L-Glutamate
C03287  L-Glutamyl 5-phosphate
C01165  L-Glutamate 5-semialdehyde
C00077  L-Ornithine
C03912  (S)-1-Pyrroline-5-carboxylate
C00148  L-Proline
Reference
  Authors
AJ Delauney, DPS Verma.
  Title
Proline biosynthesis and osmoregulation in plants.
  Journal
Plant J. 4(2):215-223 (1993)
DOI:10.1046/j.1365-313X.1993.04020215.x
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