KEGG   REACTION: R01251
Entry
R01251                      Reaction                               
Name
L-proline:NADP+ 5-oxidoreductase
Definition
L-Proline + NADP+ <=> (S)-1-Pyrroline-5-carboxylate + NADPH + H+
Equation
C00148 + C00006 <=> C03912 + C00005 + C00080
Comment
NADH (see R01248)
Reaction class
RC00001  C00005_C00006
RC00083  C00148_C03912
Enzyme
1.5.1.2
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00015  Proline biosynthesis, glutamate => proline
M00972  Proline metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.2
     R01251  L-Proline + NADP+ <=> (S)-1-Pyrroline-5-carboxylate + NADPH + H+
Orthology
K00286  pyrroline-5-carboxylate reductase [EC:1.5.1.2]
Other DBs
RHEA: 14112
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