MODULE: M00037
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Entry
M00037 Pathway Module
Name
Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Definition
K00502 K01593 K00669 K00543
Diagram
Orthology
K00502
tryptophan 5-monooxygenase [EC:
1.14.16.4
] [RN:
R01814
]
K01593
aromatic-L-amino-acid decarboxylase [EC:
4.1.1.28
] [RN:
R02701
]
K00669
arylalkylamine N-acetyltransferase [EC:
2.3.1.87
] [RN:
R02911
]
K00543
acetylserotonin N-methyltransferase [EC:
2.1.1.4
] [RN:
R03130
]
Ortholog table
Taxonomy
Class
Pathway modules; Amino acid metabolism; Aromatic amino acid metabolism
BRITE hierarchy
Pathway
map00380
Tryptophan metabolism
map01100
Metabolic pathways
Reaction
R01814
C00078
->
C00643
R02701
C00643
->
C00780
R02911
C00780
->
C00978
R03130
C00978
->
C01598
Compound
C00078
L-Tryptophan
C00643
5-Hydroxy-L-tryptophan
C00780
Serotonin
C00978
N-Acetylserotonin
C01598
Melatonin
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