KEGG   MODULE: M00120
Entry
M00120            Pathway   Module                                 
Name
Coenzyme A biosynthesis, pantothenate => CoA
Definition
(K00867,K03525,K01947,K09680) ((K01922,K21977) K01598,K13038) (K02318,(K00954,K02201) K00859)
Diagram
M00120

Orthology
K00867,K03525,K01947,K09680  
pantothenate kinase [EC:2.7.1.33] [RN:R03018]
K01922  
phosphopantothenate---cysteine ligase (ATP) [EC:6.3.2.51] [RN:R04230]
K21977,K13038  
phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5] [RN:R04231]
K01598,K13038  
phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] [RN:R03269]
K02318,K00954,K02201 pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] [RN:R03035]  
 
K02318,K00859  
dephospho-CoA kinase [EC:2.7.1.24] [RN:R00130]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00770  Pantothenate and CoA biosynthesis
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
R03018  
R04230,R04231  
R03269  
R03035  
R00130  
Compound
C00864  Pantothenate
C03492  D-4'-Phosphopantothenate
C04352  (R)-4'-Phosphopantothenoyl-L-cysteine
C01134  Pantetheine 4'-phosphate
C00882  Dephospho-CoA
C00010  CoA
Reference
PMID:15893380
  Authors
Leonardi R, Zhang YM, Rock CO, Jackowski S
  Title
Coenzyme A: back in action.
  Journal
Prog Lipid Res 44:125-53 (2005)
DOI:10.1016/j.plipres.2005.04.001
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