KEGG   MODULE: M00535
Entry
M00535            Pathway   Module                                 
Name
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Definition
K09011 K01703+K01704 K00052
Diagram
M00535

Orthology
K09011  
cimA; D-citramalate synthase [EC:2.3.3.21] [RN:R07399]
K01703,K01704  
leuCD; 3-isopropylmalate/(R)-2-methylmalate dehydratase [EC:4.2.1.33 4.2.1.35] [RN:R03896 R03898]
K00052  
leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] [RN:R00994]
Class
Pathway modules; Amino acid metabolism; Branched-chain amino acid metabolism
Pathway
map00290  Valine, leucine and isoleucine biosynthesis
map00660  C5-Branched dibasic acid metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Reaction
R07399  
R03896  
R03898  
R00994  
Compound
C00022  Pyruvate
C02612  (R)-2-Methylmalate
C02226  2-Methylmaleate
C06032  D-erythro-3-Methylmalate
C00109  2-Oxobutanoate
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
LinkDB

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