KEGG   MODULE: M00779
Entry
M00779            Pathway   Module                                 
Name
Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
Definition
K05556 (K14626,K14627) (K14628,K14629) (K14630+K14631,K14632)
Diagram
M00779  Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
M00779

Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Type II polyketide biosynthesis
Pathway
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K05556  
actVI1; ketoreductase RED1 [EC:1.1.1.-] [RN:R09306 R09307 R09308]
K14626  
actVIA; actinorhodin biosynthesis protein ActVIA [RN:R09308]
K14627  
actVI3; dehydratase [EC:4.2.1.-] [RN:R09308]
K14628  
actVI2; enoyl reductase [RN:R06695]
K14629  
actVI4; enoyl reductase [RN:R06695]
K14630  
actVA5; two-component flavin-dependent monooxygenase [EC:1.14.14.-] [RN:R09314]
K14631  
actVB; flavin reductase ActVB [EC:1.5.1.-] [RN:R05705]
K14632  
actVA6; C-6 monooxygenase [RN:R06696]
Complete
sco  Streptomyces coelicolor
slv  Streptomyces lividans
scya  Streptomyces cyaneochromogenes
Reaction
R09306  
R09307  
R09308  
R06695  
R09314+R05705+R06696  
Compound
C18353  Octaketide bicyclic intermediate
C18354  (S)-Chiral alcohol
C18356  (S)-Hemiketal
C12434  (S)-DNPA
C12435  6-Deoxydihydrokalafungin
C12436  Dihydrokalafungin
LinkDB

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