KEGG   MODULE: M00825
Entry
M00825            Pathway   Module                                 
Name
10-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 10-membered enediyne core
Definition
K15314 K21168+K21169+K21170+K21171+K21172+K21173+K21174
Diagram
M00825  10-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 10-membered enediyne core
M00825

Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Enediyne biosynthesis
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K15314  
sgcE; enediyne polyketide synthase [RN:R11435]
K21168  
calE1; enediyne biosynthesis protein CalE1
K21169  
calE2; enediyne biosynthesis protein CalE2
K21170  
calE3; enediyne biosynthesis protein CalE3
K21171  
calE4; enediyne biosynthesis protein CalE4
K21172  
calE5; enediyne biosynthesis protein CalE5
K21173  
calE6; methionine gamma-lyase
K21174  
calE9; enediyne biosynthesis protein CalE9
Complete
1877  Micromonospora echinospora
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
LinkDB

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