| Entry |
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| Name |
Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
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| Definition |
K22699
K03147 ((K00941 (K00788,K21220)),K21219) K00946
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| Diagram |
| M00896 | Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP |
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| Class |
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
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| Pathway |
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| Orthology |
thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC: 2.4.2.59] [RN: R12026] thiE,thiN; thiamine-phosphate diphosphorylase [EC: 2.5.1.3] [RN: R10712] |
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| Complete |
| bbar | Beijerinckiaceae bacterium RH AL1 |
| dma | Solidesulfovibrio magneticus |
| dcb | Solidesulfovibrio carbinolicus |
| soli | Solidesulfovibrio sp. DCME |
| dgg | Megalodesulfovibrio gigas |
| dms | Oceanidesulfovibrio marinus |
| daf | Desulfocurvibacter africanus subsp. africanus |
| dsx | Desulfolutivibrio sulfoxidireducens |
| dsd | Desulfolutivibrio sulfodismutans |
| dal | Desulfatibacillum aliphaticivorans |
| dao | Desulfobacca acetoxidans |
| dax | Desulfoglaeba alkanexedens |
| dbr | Desulfarculus baarsii |
| dmp | Desulfoferula mesophila |
| tid | Thermodesulfatator indicus |
| top | Thermodesulfobacterium geofontis |
| tcm | Thermodesulfobacterium commune |
| thet | Thermodesulfobacterium sp. TA1 |
| cthi | Caldimicrobium thiodismutans |
| tav | Thermosulfuriphilus ammonigenes |
| tmai | Thermosulfurimonas marina |
| daw | Desulfofervidus auxilii |
| mzl | Mycalebacterium zealandia |
| lbv | Lentisphaerota bacterium zth2 |
| bcel | Bacteroides cellulosilyticus |
| bis | Bacteroides intestinalis |
| psoe | Porphyromonas somerae |
| pdi | Parabacteroides distasonis |
| parc | Parabacteroides sp. CT06 |
| pmer | Parabacteroides merdae |
| pgol | Parabacteroides goldsteinii |
| pjo | Parabacteroides johnsonii |
| pfai | Parabacteroides faecis |
| pves | Parabacteroides vesiculifaciens |
| pmz | Prevotella melaninogenica |
| pit | Prevotella intermedia |
| pni | Prevotella nigrescens |
| pher | Prevotella herbatica |
| pmik | Prevotella mikamonis |
| rbc | Mucinivorans hirudinis |
| ttz | Tenuifilum thalassicum |
| mbas | Labilibaculum antarcticum |
| paa | Prosthecochloris aestuarii |
| proc | Prosthecochloris sp. CIB 2401 |
| prs | Prosthecochloris sp. HL-130-GSB |
| pros | Prosthecochloris sp. GSB1 |
| tam | Thermovibrio ammonificans |
| dte | Desulfurobacterium thermolithotrophum |
| ttk | Thermosulfidibacter takaii |
| nmv | Nitrospira moscoviensis |
| nall | Nitrospira allomarina |
| nneo | Nitrospira neomarina |
| dhr | Dissulfurimicrobium hydrothermale |
| mbx | Mycobacterium tuberculosis variant bovis BCG ATCC 35743 |
| mphl | Mycolicibacterium phlei |
| slk | Streptomyces lunaelactis |
| fsh | Fervidibacter sacchari |
| mja | Methanocaldococcus jannaschii |
| mfe | Methanocaldococcus fervens |
| mvu | Methanocaldococcus vulcanius |
| mfs | Methanocaldococcus sp. FS406-22 |
| mif | Methanocaldococcus infernus |
| mjh | Methanocaldococcus bathoardescens |
| mesg | Methanocaldococcus lauensis SG7 |
| mesa | Methanocaldococcus lauensis SG1 |
| mmp | Methanococcus maripaludis S2 |
| mmq | Methanococcus maripaludis C5 |
| mmx | Methanococcus maripaludis C6 |
| mmz | Methanococcus maripaludis C7 |
| mmak | Methanococcus maripaludis KA1 |
| mmao | Methanococcus maripaludis OS7 |
| mmad | Methanococcus maripaludis DSM 2067 |
| mae | Methanococcus aeolicus |
| mvn | Methanococcus vannielii |
| mmvi | Methanococcus mangrovi |
| mok | Methanothermococcus okinawensis |
| meax | Methanothermococcus jasoni |
| metf | Methanofervidicoccus sp. A16 |
| mth | Methanothermobacter thermautotrophicus |
| mmg | Methanothermobacter marburgensis |
| mwo | Methanothermobacter wolfeii |
| mtee | Methanothermobacter tenebrarum |
| metc | Methanothermobacter sp. CaT2 |
| mete | Methanothermobacter sp. EMTCatA1 |
| metz | Methanothermobacter sp. MT-2 |
| metk | Methanothermobacter sp. KEPCO-1 |
| mthm | Methanothermobacter sp. THM-1 |
| metj | Methanothermobacter sp. THM-2 |
| meb | Methanobrevibacter sp. AbM4 |
| mel | Methanobacterium lacus |
| mew | Methanobacterium paludis |
| meth | Methanobacterium sp. MB1 |
| mfc | Methanobacterium formicicum BRM9 |
| mfi | Methanobacterium formicicum DSM1535 |
| mcub | Methanobacterium congolense |
| msub | Methanobacterium subterraneum |
| metn | Methanobacterium sp. MZ-A1 |
| mett | Methanobacterium sp. BRmetb2 |
| meto | Methanobacterium sp. BAmetb5 |
| meme | Methanobacterium alkalithermotolerans |
| mfeg | Methanobacterium ferruginis |
| meer | Methanobacterium sp. ERen5 |
| mrid | Methanobacterium aridiramus |
| mfv | Methanothermus fervidus |
| msoc | Methanothermus sociabilis |
| mka | Methanopyrus kandleri |
| afu | Archaeoglobus fulgidus DSM 4304 |
| afg | Archaeoglobus fulgidus DSM 8774 |
| apo | Archaeoglobus profundus |
| ave | Archaeoglobus veneficus |
| gac | Geoglobus acetivorans |
| pfu | Pyrococcus furiosus DSM 3638 |
| pfi | Pyrococcus furiosus COM1 |
| pyc | Pyrococcus kukulkanii |
| tko | Thermococcus kodakarensis |
| tga | Thermococcus gammatolerans |
| the | Thermococcus sp. 4557 |
| thm | Thermococcus cleftensis |
| tlt | Thermococcus litoralis |
| ths | Thermococcus paralvinellae |
| teu | Thermococcus eurythermalis |
| tgy | Thermococcus guaymasensis |
| thv | Thermococcus sp. 2319x1 |
| tch | Thermococcus chitonophagus |
| tpep | Thermococcus peptonophilus |
| tpie | Thermococcus piezophilus |
| ttd | Thermococcus thioreducens |
| tprf | Thermococcus profundus |
| tpaf | Thermococcus pacificus |
| them | Thermococcus aciditolerans |
| ppac | Palaeococcus pacificus |
| mba | Methanosarcina barkeri Fusaro |
| mby | Methanosarcina barkeri MS |
| mbw | Methanosarcina barkeri Wiesmoor |
| mbar | Methanosarcina barkeri 227 |
| mbak | Methanosarcina barkeri 3 |
| mac | Methanosarcina acetivorans |
| mma | Methanosarcina mazei Go1 |
| mmj | Methanosarcina mazei S-6 |
| mmac | Methanosarcina mazei C16 |
| mvc | Methanosarcina vacuolata |
| mek | Methanosarcina sp. Kolksee |
| mls | Methanosarcina lacustris |
| metm | Methanosarcina sp. MTP4 |
| mef | Methanosarcina sp. WH1 |
| meq | Methanosarcina sp. WWM596 |
| msj | Methanosarcina siciliae C2J |
| msz | Methanosarcina siciliae HI350 |
| msw | Methanosarcina siciliae T4/M |
| mthr | Methanosarcina thermophila TM-1 |
| mthe | Methanosarcina thermophila CHTI-55 |
| mhor | Methanosarcina horonobensis |
| mfz | Methanosarcina flavescens |
| mhab | Methanosarcina hadiensis |
| metw | Methanosarcina sp. 795 |
| mmaj | Methanosarcina mangrovi |
| msds | Methanosarcina sediminis |
| mbu | Methanococcoides burtonii |
| mmet | Methanococcoides methylutens |
| melo | Methanococcoides orientis |
| mmap | Methanococcoides mangrovi |
| msel | Methanococcoides seepicolus |
| mmh | Methanohalophilus mahii |
| mhaz | Methanohalophilus halophilus |
| mpot | Methanohalophilus portucalensis |
| mev | Methanohalobium evestigatum |
| mzh | Methanosalsum zhilinae |
| mmav | Methanolobus mangrovi |
| mseb | Methanolobus sediminis |
| mezk | Methanolobus sp. ZRKC1 |
| mtp | Methanothrix thermoacetophila |
| mcj | Methanothrix soehngenii |
| mhi | Methanothrix harundinacea |
| mhu | Methanospirillum hungatei |
| mrtj | Methanospirillum purgamenti |
| mla | Methanocorpusculum labreanum |
| mem | Methanoculleus marisnigri |
| mbg | Methanoculleus bourgensis MS2 |
| mema | Methanoculleus bourgensis MAB1 |
| mchk | Methanoculleus chikugoensis |
| msum | Methanoculleus submarinus |
| mrc | Methanoculleus receptaculi |
| mpi | Methanolacinia petrolearia |
| mend | Methanoplanus endosymbiosus |
| mefw | Methanochimaera problematica |
| maqe | Methanofollis aquaemaris |
| mfk | Methanofollis formosanus |
| mou | Methanogenium organophilum |
| mesb | Methanogenium sp. S4BF |
| manq | Methanomicrobium antiquum |
| mez | Methanocella conradii |
| hal | Halobacterium salinarum NRC-1 |
| hsl | Halobacterium salinarum R1 |
| hanr | Halobacterium salinarum NRC-34001 |
| hhb | Halobacterium hubeiense |
| hags | Halobacterium sp. GSL-19 |
| habo | Halobacterium sp. BOL4-2 |
| hno | Halobacterium noricense |
| hlu | Halobacterium litoreum |
| hanx | Halobacterium sp. NMX12-1 |
| hsu | Halanaeroarchaeum sulfurireducens HSR2 |
| hsf | Halanaeroarchaeum sulfurireducens M27-SA2 |
| salr | Salarchaeum sp. JOR-1 |
| hdo | Halococcus dombrowskii |
| hayc | Halorussus salilacus |
| sali | Salinarchaeum sp. Harcht-Bsk1 |
| saim | Salinarchaeum sp. IM2453 |
| hma | Haloarcula marismortui ATCC 43049 |
| hsin | Haloarcula marismortui ATCC 33800 |
| hhi | Haloarcula hispanica ATCC 33960 |
| hhn | Haloarcula hispanica N601 |
| hab | Haloarcula sp. CBA1115 |
| hta | Haloarcula taiwanensis |
| halj | Haloarcula sp. JP-L23 |
| hut | Halorhabdus utahensis |
| hala | Halorhabdus sp. CBA1104 |
| hasv | Halorhabdus sp. SVX81 |
| habn | Halorhabdus sp. BNX81 |
| hmu | Halomicrobium mukohataei |
| halz | Halomicrobium mukohataei JP60 |
| hall | Halomicrobium sp. LC1Hm |
| hazp | Halomicrobium sp. ZPS1 |
| hali | Halorientalis sp. IM1011 |
| hpal | Halorientalis pallida |
| hpel | Halosimplex pelagicum |
| harc | Halococcoides cellulosivorans |
| nph | Natronomonas pharaonis |
| hvo | Haloferax volcanii DS2 |
| hale | Haloferax volcanii wsp1 |
| hln | Haloferax volcanii SVX82 |
| hme | Haloferax mediterranei |
| hdr | Haloferax denitrificans |
| hbo | Halogeometricum borinquense |
| hezz | Halorubrum ezzemoulense |
| hsai | Halorubrum salinarum |
| halg | Halorarum halophilum |
| hmp | Halobaculum magnesiiphilum |
| htu | Haloterrigena turkmenica |
| hsal | Haloterrigena salifodinae |
| hakz | Haloterrigena alkaliphila |
| hxa | Halopiger xanaduensis |
| npe | Natrinema pellirubrum |
| haly | Natrinema halophilum |
| hjt | Natrinema thermotolerans |
| nge | Natronobacterium gregoryi |
| hlc | Natronobacterium lacisalsi |
| nou | Natronococcus occultus |
| hlr | Halostagnicola larsenii |
| naj | Natrarchaeobaculum aegyptiacum |
| nara | Natrialbaceae archaeon AArc-T1-2 |
| nbg | Natronorubrum bangense |
| nas | Natronorubrum aibiense |
| hda | Natronorubrum daqingense |
| melu | Methanoliparum sp. LAM-1 |
| meam | Methanonatronarchaeum sp. AMET6-2 |
| meae | Methanonatronarchaeum sp. AMET-Sl |
| abi | Aciduliprofundum boonei |
| acf | Aciduliprofundum sp. MAR08-339 |
| iho | Ignicoccus hospitalis |
| iis | Ignicoccus islandicus |
| dka | Desulfurococcus amylolyticus 1221n |
| dfd | Desulfurococcus amylolyticus DSM 16532 |
| iag | Ignisphaera aggregans |
| thg | Thermogladius calderae |
| hbu | Hyperthermus butylicus |
| sto | Sulfurisphaera tokodaii |
| soh | Sulfurisphaera ohwakuensis |
| sjv | Sulfurisphaera javensis |
| sso | Saccharolobus solfataricus P2 |
| sol | Saccharolobus solfataricus 98/2 |
| ssoa | Saccharolobus solfataricus SULA |
| sshi | Saccharolobus shibatae |
| scas | Saccharolobus caldissimus |
| sis | Saccharolobus islandicus L.S.2.15 |
| sia | Saccharolobus islandicus M.14.25 |
| sim | Saccharolobus islandicus M.16.27 |
| sid | Saccharolobus islandicus M.16.4 |
| sula | Saccharolobus sp. A20 |
| sule | Saccharolobus sp. E5-1-F |
| sai | Sulfolobus acidocaldarius DSM 639 |
| sacn | Sulfolobus acidocaldarius N8 |
| sacr | Sulfolobus acidocaldarius Ron12/I |
| sacs | Sulfolobus acidocaldarius SUSAZ |
| sull | Sulfolobus sp. S-194 |
| mse | Metallosphaera sedula DSM 5348 |
| mpru | Metallosphaera sedula Ron 12/II |
| mcn | Metallosphaera cuprina |
| mten | Metallosphaera tengchongensis |
| mjn | Metallosphaera javensis |
| aman | Acidianus manzaensis |
| asul | Acidianus sulfidivorans |
| aamb | Acidianus ambivalens |
| sazo | Stygiolobus azoricus |
| csty | Stygiolobus caldivivus |
| step | Sulfuracidifex tepidarius |
| smet | Sulfuracidifex metallicus |
| pai | Pyrobaculum aerophilum |
| pis | Pyrobaculum islandicum |
| pog | Pyrobaculum oguniense |
| tne | Pyrobaculum neutrophilum |
| vdi | Vulcanisaeta distributa |
| nmr | Nitrosopumilus maritimus |
| nir | Nitrosopumilus sediminis |
| nkr | Nitrosopumilus koreensis |
| nid | Nitrosopumilus piranensis |
| nin | Nitrosopumilus adriaticus |
| niw | Nitrosopumilus sp. SW |
| ncl | Nitrosopumilus cobalaminigenes |
| nox | Nitrosopumilus oxyclinae |
| nue | Nitrosopumilus ureiphilus |
| nip | Nitrosopumilus sp. K4 |
| nzt | Nitrosopumilus zosterae |
| nct | Nitrosomarinus catalinensis |
| nic | Nitrosarchaeum sp. AC2 |
| nga | Nitrososphaera gargensis |
| nvn | Nitrososphaera viennensis |
| nev | Nitrososphaera evergladensis |
| ncv | Nitrosocaldus cavascurensis |
| ndv | Nitrosotalea devaniterrae |
| csy | Cenarchaeum symbiosum |
| nbv | Nitrosopelagicus brevis |
| tah | Nitrosotenuis cloacae |
| niu | Nitrosotenuis sp. DW1 |
| barb | Bathyarchaeota archaeon BA2 |
| flt | Fermentimicrarchaeum limneticum |
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| Reaction |
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| Compound |
| C20784 | ADP-5-ethyl-4-methylthiazole-2-carboxylate |
| C20247 | 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate |
| C03373 | Aminoimidazole ribotide |
| C04556 | 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine |
| C04752 | 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate |
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| Reference |
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| Authors |
Hayashi M, Kijima Y, Tazuya-Murayama K, Yamada K |
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| Title |
The Biosynthesis of the Thiazole Moiety of Thiamin in the Archaeon Halobacterium salinarum. |
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| Journal |
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| Reference |
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| Authors |
Kijima Y, Hayashi M, Yamada K, Tazuya-Murayama K |
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| Title |
The Biosynthesis of the Pyrimidine Moiety of Thiamin in Halobacterium salinarum. |
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| Journal |
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| LinkDB |
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