KEGG   MODULE: M00929
Entry
M00929            Pathway   Module                                 
Name
Gibberellin A1 biosynthesis, GGPP => GA1
Definition
K20657 K21292 K12917 K12918 K12919
Diagram
M00929

Orthology
K20657  
ent-copalyl diphosphate/ent-kaurene synthase [EC:5.5.1.13 4.2.3.19] [RN:R02068 R05092]
K21292  
ent-kaurene oxidase [EC:1.14.14.86] [RN:R06291 R06292 R06293]
K12917  
P450I; cytochrome P450 monooxygenase 1 [RN:R06294 R06295 R06341 R06339]
K12918  
P450II; cytochrome P450 monooxygenase 2 [RN:R06324 R06325 R06327]
K12919  
P450III; cytochrome P450 monooxygenase 3 [RN:R06619]
Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Plant terpenoid biosynthesis
Pathway
map00904  Diterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R02068  
R05092  
R06291  
R06292  
R06293  
R06294  
R06295  
R06341  
R06339  
R06324  
R06325  
R06327  
R06619  
Compound
C00353  Geranylgeranyl diphosphate
C06089  ent-Copalyl diphosphate
C06090  ent-Kaurene
C11872  Kaur-16-en-18-ol
C11873  Kaur-16-en-18-al
C11874  Kaur-16-en-18-oic acid
C11875  ent-7alpha-Hydroxykaur-16-en-19-oic acid
C06093  Gibberellin A12 aldehyde
C11853  Gibberellin A14 aldehyde
C11858  Gibberellin A14
C11859  Gibberellin A37 open lactone
C11862  Gibberellin A36
C11864  Gibberellin A4
C00859  Gibberellin A1
Reference
PMID:11943776
  Authors
Tudzynski B, Rojas MC, Gaskin P, Hedden P
  Title
The gibberellin 20-oxidase of Gibberella fujikuroi is a multifunctional monooxygenase.
  Journal
J Biol Chem 277:21246-53 (2002)
DOI:10.1074/jbc.M201651200
Reference
PMID:12750377
  Authors
Tudzynski B, Mihlan M, Rojas MC, Linnemannstons P, Gaskin P, Hedden P
  Title
Characterization of the final two genes of the gibberellin biosynthesis gene cluster of Gibberella fujikuroi: des and P450-3 encode GA4 desaturase and the 13-hydroxylase, respectively.
  Journal
J Biol Chem 278:28635-43 (2003)
DOI:10.1074/jbc.M301927200
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