| Entry |
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| Name |
Phylloquinone biosynthesis, chorismate (+ phytyl-PP) => phylloquinol
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| Definition |
((K02552 K02551 K08680 K02549),K14759) (K01911,K14760) K01661 (K19222,K12073) K23094 K17872 K23095
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| Diagram |
| M00932 | Phylloquinone biosynthesis, chorismate (+ phytyl-PP) => phylloquinol |
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| Class |
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
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| Pathway |
| map00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
| map01110 | Biosynthesis of secondary metabolites |
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| Orthology |
menF; menaquinone-specific isochorismate synthase [EC: 5.4.4.2] [RN: R01717] menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC: 2.2.1.9] [RN: R08165] menH; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC: 4.2.99.20] [RN: R08166] menI, DHNAT; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [EC: 3.1.2.28] [RN: R07262] ABC4, menA; 2-carboxy-1,4-naphthoquinone phytyltransferase [EC: 2.5.1.130] [RN: R12255] MENG, menG; demethylphylloquinol methyltransferase [EC: 2.1.1.329] [RN: R04994] |
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| Complete |
| ath | Arabidopsis thaliana (thale cress) |
| aly | Arabidopsis lyrata (lyrate rockcress) |
| crb | Capsella rubella (pink shepherd's-purse) |
| csat | Camelina sativa (false flax) |
| eus | Eutrema salsugineum (saltwater cress) |
| brp | Brassica rapa (field mustard) |
| bna | Brassica napus (rape) |
| boe | Brassica oleracea (wild cabbage) |
| rsz | Raphanus sativus (radish) |
| thj | Tarenaya hassleriana (spider flower) |
| cit | Citrus sinensis (Valencia orange) |
| cic | Citrus x clementina (clementine) |
| pvy | Pistacia vera (pistachio) |
| minc | Mangifera indica (mango) |
| tcc | Theobroma cacao (cacao) |
| ghi | Gossypium hirsutum (upland cotton) |
| gab | Gossypium arboreum (tree cotton) |
| hsyr | Hibiscus syriacus (Rose-of-Sharon) |
| dzi | Durio zibethinus (durian) |
| egr | Eucalyptus grandis (rose gum) |
| rarg | Rhodamnia argentea (silver malletwood) |
| gmx | Glycine max (soybean) |
| gsj | Glycine soja (wild soybean) |
| pvu | Phaseolus vulgaris (common bean) |
| vra | Vigna radiata (mung bean) |
| var | Vigna angularis (adzuki bean) |
| vun | Vigna unguiculata (cowpea) |
| ccaj | Cajanus cajan (pigeon pea) |
| aprc | Abrus precatorius (Indian licorice) |
| mtr | Medicago truncatula (barrel medic) |
| tpra | Trifolium pratense (red clover) |
| cam | Cicer arietinum (chickpea) |
| psat | Lathyrus oleraceus (garden pea) |
| vvo | Vicia villosa (hairy vetch) |
| ahf | Arachis hypogaea (peanut) |
| lang | Lupinus angustifolius (narrow-leaved blue lupine) |
| qsa | Quillaja saponaria (soapbark tree) |
| fve | Fragaria vesca (woodland strawberry) |
| aans | Argentina anserina (silverweed cinquefoil) |
| rcn | Rosa chinensis (China rose) |
| pper | Prunus persica (peach) |
| pmum | Prunus mume (Japanese apricot) |
| pavi | Prunus avium (sweet cherry) |
| pdul | Prunus dulcis (almond) |
| mdm | Malus domestica (apple) |
| msyl | Malus sylvestris (European crab apple) |
| pcox | Pyrus communis (pear) |
| csav | Cannabis sativa (hemp) |
| hlp | Humulus lupulus (common hop) |
| csv | Cucumis sativus (cucumber) |
| cmo | Cucumis melo (muskmelon) |
| bhj | Benincasa hispida (wax gourd) |
| mcha | Momordica charantia (bitter melon) |
| cmax | Cucurbita maxima (winter squash) |
| cmos | Cucurbita moschata (crookneck pumpkin) |
| cpep | Cucurbita pepo subsp. pepo (vegetable marrow) |
| rcu | Ricinus communis (castor bean) |
| mean | Mercurialis annua (annual mercury) |
| jcu | Jatropha curcas (Barbados nut) |
| hbr | Hevea brasiliensis (rubber tree) |
| mesc | Manihot esculenta (cassava) |
| pop | Populus trichocarpa (black cottonwood) |
| peu | Populus euphratica (Euphrates poplar) |
| palz | Populus alba (white poplar) |
| pnz | Populus nigra (Lombardy poplar) |
| jre | Juglans regia (English walnut) |
| cill | Carya illinoinensis (pecan) |
| cave | Corylus avellana (European hazelnut) |
| aglu | Alnus glutinosa (common alder) |
| qsu | Quercus suber (cork oak) |
| qlo | Quercus lobata (valley oak) |
| csaa | Castanea sativa (European chestnut) |
| twl | Tripterygium wilfordii (thunder duke vine) |
| vvi | Vitis vinifera (wine grape) |
| vri | Vitis riparia (riverbank grape) |
| sly | Solanum lycopersicum (tomato) |
| sot | Solanum tuberosum (potato) |
| sdul | Solanum dulcamara (climbing nightshade) |
| cann | Capsicum annuum (peppers) |
| lbb | Lycium barbarum (goji berry) |
| nta | Nicotiana tabacum (common tobacco) |
| nsy | Nicotiana sylvestris (wood tobacco) |
| nto | Nicotiana tomentosiformis |
| nau | Nicotiana attenuata (coyote tobacco) |
| ini | Ipomoea nil (Japanese morning glory) |
| itr | Ipomoea triloba (trilobed morning glory) |
| sind | Sesamum indicum (sesame) |
| oeu | Olea europaea var. sylvestris (wild olive) |
| egt | Erythranthe guttata (spotted monkey flower) |
| sspl | Salvia splendens (scarlet sage) |
| apan | Andrographis paniculata |
| carb | Coffea arabica (coffee) |
| han | Helianthus annuus (common sunflower) |
| ecad | Erigeron canadensis (horseweed) |
| lsv | Lactuca sativa (garden lettuce) |
| ccav | Cynara cardunculus var. scolymus (artichoke) |
| dcr | Daucus carota (carrot) |
| agrv | Apium graveolens (celery) |
| csin | Camellia sinensis (tea plant) |
| aew | Actinidia eriantha (wild kiwifruit) |
| dlt | Diospyros lotus (date-plum) |
| bvg | Beta vulgaris (sugar beet) |
| soe | Spinacia oleracea (spinach) |
| cqi | Chenopodium quinoa (quinoa) |
| atri | Amaranthus tricolor (tampala) |
| slaf | Silene latifolia (white campion) |
| nnu | Nelumbo nucifera (sacred lotus) |
| tss | Telopea speciosissima (New South Wales waratah) |
| psom | Papaver somniferum (opium poppy) |
| osa | Oryza sativa japonica (Japanese rice) |
| obr | Oryza brachyantha (malo sina) |
| ogl | Oryza glaberrima (African rice) |
| bdi | Brachypodium distachyon (stiff brome) |
| ats | Aegilops tauschii (wheat D) |
| tdc | Triticum dicoccoides (wild emmer wheat) |
| taes | Triticum aestivum (bread wheat) |
| tua | Triticum urartu (red wild einkorn wheat) |
| hvg | Hordeum vulgare subsp. vulgare (domesticated barley) |
| lper | Lolium perenne (perennial ryegrass) |
| lrd | Lolium rigidum (rigid ryegrass) |
| sbi | Sorghum bicolor (sorghum) |
| mflo | Miscanthus floridulus |
| sita | Setaria italica (foxtail millet) |
| svs | Setaria viridis (green foxtail) |
| pvir | Panicum virgatum (switchgrass) |
| phai | Panicum hallii (Hall's panicgrass) |
| paua | Phragmites australis (common reed) |
| tang | Typha angustifolia (narrow-leaf cattail) |
| pda | Phoenix dactylifera (date palm) |
| egu | Elaeis guineensis (African oil palm) |
| mus | Musa acuminata (dessert banana) |
| zof | Zingiber officinale (ginger) |
| peq | Phalaenopsis equestris |
| aof | Asparagus officinalis (garden asparagus) |
| acak | Aristolochia californica |
| ncol | Nymphaea colorata (blue-petal water lily) |
| cjf | Cryptomeria japonica (Japanese cedar) |
| smo | Selaginella moellendorffii |
| ppp | Physcomitrium patens (spreading earthmoss) |
| syns | Synechocystis sp. LKSZ1 |
| len | Leptolyngbya sp. NIES-3755 |
| lsk | Leptothermofonsia sichuanensis |
| pgx | Pseudanabaena galeata |
| chon | Chondrocystis sp. NIES-4102 |
| cyp | Rippkaea orientalis PCC 8801 |
| cyh | Rippkaea orientalis PCC 8802 |
| ter | Trichodesmium erythraeum |
| pagh | Planktothrix agardhii |
| prun | Planktothrix rubescens |
| mvag | Microcoleus vaginatus |
| lfs | Limnospira fusiformis |
| oni | Oscillatoria nigro-viridis |
| mic | Allocoleopsis franciscana |
| nost | Nostoc sp. ATCC 53789 |
| nosq | Nostoc sp. UHCC 0926 |
| nosc | Nostoc sp. UHCC 0870 |
| ava | Trichormus variabilis |
| naz | 'Nostoc azollae' 0708 |
| csg | Cylindrospermum stagnale |
| nsph | Nodularia sphaerocarpa |
| aee | Anabaenopsis elenkinii |
| alih | Aliinostoc sp. HNIBRCY26 |
| calo | Calothrix sp. PCC 7507 |
| calt | Calothrix sp. PCC 6303 |
| caln | Calothrix sp. NIES-2098 |
| cals | Calothrix sp. NIES-3974 |
| riv | Rivularia sp. PCC 7116 |
| mdp | Microchaete diplosiphon |
| fis | Fischerella sp. NIES-3754 |
| dou | Dolichospermum sp. UHCC 0315A |
| dfs | Dolichospermum flos-aquae |
| dcm | Dolichospermum compactum |
| dot | Dolichospermum sp. DET69 |
| doz | Dolichospermum sp. UKL201 |
| doc | Dolichospermum sp. DL01 |
| crk | Cylindrospermopsis raciborskii |
| aflo | Aphanizomenon flos-aquae |
| stoq | Sphaerospermopsis torques-reginae |
| skv | Sphaerospermopsis kisseleviana |
| ccur | Cylindrospermopsis curvispora |
| ocf | Okeanomitos corallinicola |
| toq | Tolypothrix sp. PCC 7910 |
| toi | Tolypothrix sp. PCC 7601 |
| toz | Tolypothrix sp. PCC 7712 |
| scys | Kalymmatonema gypsitolerans |
| ncn | Nostocales cyanobacterium HT-58-2 |
| scs | Stanieria cyanosphaera |
| stan | Stanieria sp. NIES-3757 |
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| Reaction |
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| Compound |
| C16519 | 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate |
| C05817 | (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate |
| C15547 | 1,4-Dihydroxy-2-naphthoyl-CoA |
| C03657 | 1,4-Dihydroxy-2-naphthoate |
| C22039 | 2-Carboxy-1,4-naphthoquinone |
| C13309 | 2-Phytyl-1,4-naphthoquinone |
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| Reference |
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| Authors |
Widhalm JR, van Oostende C, Furt F, Basset GJ |
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| Title |
A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1. |
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| Journal |
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| Reference |
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| Authors |
Babujee L, Wurtz V, Ma C, Lueder F, Soni P, van Dorsselaer A, Reumann S |
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| Title |
The proteome map of spinach leaf peroxisomes indicates partial compartmentalization of phylloquinone (vitamin K1) biosynthesis in plant peroxisomes. |
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| Journal |
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| LinkDB |
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