KEGG   MODULE: M00939
Entry
M00939            Pathway   Module                                 
Name
Pyrimidine degradation, uracil => 3-hydroxypropanoate
Definition
K09018+K09024 K09020 K09021 K09023 (K09019,K16066)
Diagram
M00939

Orthology
K09018,K09024  
rutA; pyrimidine oxygenase [EC:1.14.99.46] [RN:R09936]
K09020  
rutB; ureidoacrylate peracid hydrolase [EC:3.5.1.110] [RN:R09947]
K09021  
rutC; aminoacrylate peracid reductase [RN:R09982]
K09023  
rutD; aminoacrylate hydrolase [EC:3.5.1.-] [RN:R09983]
K09019,K16066  
rutE; 3-hydroxypropanoate dehydrogenase [EC:1.1.1.-] [RN:R09289]
Class
Pathway modules; Nucleotide metabolism; Pyrimidine metabolism
Pathway
map00240  Pyrimidine metabolism
map01100  Metabolic pathways
Reaction
R09936  
R09947  
R09982  
R09983  
R09289  
Compound
C00106  Uracil
C20231  (Z)-3-Ureidoacrylate peracid
C20249  (Z)-3-Peroxyaminoacrylate
C20253  Aminoacrylate
C00222  3-Oxopropanoate
C01013  3-Hydroxypropanoate
Reference
PMID:20400551
  Authors
Kim KS, Pelton JG, Inwood WB, Andersen U, Kustu S, Wemmer DE
  Title
The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems.
  Journal
J Bacteriol 192:4089-102 (2010)
DOI:10.1128/JB.00201-10
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