| Entry |
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| Name |
Loss of RASSF1 to RAS-RASSF1 signaling pathway
|
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| Definition |
RAS // (RASSF1*+RASSF5) // STK4 |
|---|
| Expanded |
(3265,3845,4893) // (11186v1+83593) // 6789 |
|---|
| Class |
nt06266 Non-small cell lung cancer
nt06213 Other RAS signaling (cancer)
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| Type |
Variant
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| Pathway |
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| Disease |
| H00014 | Non-small cell lung cancer |
|
|---|
| Gene |
| 3265 | HRAS; HRas proto-oncogene, GTPase |
| 3845 | KRAS; KRAS proto-oncogene, GTPase |
| 4893 | NRAS; NRAS proto-oncogene, GTPase |
| 11186 | RASSF1; Ras association domain family member 1 |
| 83593 | RASSF5; Ras association domain family member 5 |
| 6789 | STK4; serine/threonine kinase 4 |
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| Variant |
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| Reference |
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|---|
| Authors |
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS. |
|---|
| Title |
K-ras mutations in non-small-cell lung carcinoma: a review. |
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| Journal |
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| Reference |
|
|---|
| Authors |
Pfeifer GP, Dammann R. |
|---|
| Title |
Methylation of the tumor suppressor gene RASSF1A in human tumors. |
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| Journal |
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| LinkDB |
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