Entry |
|
Name |
Loss of RASSF1 to RAS-RASSF1 signaling pathway
|
Definition |
RAS // (RASSF1*+RASSF5) // STK4 |
Expanded |
(3265,3845,4893) // (11186v1+83593) // 6789 |
Class |
nt06266 Non-small cell lung cancer
nt06213 Other RAS signaling (cancer)
|
Type |
Variant
|
Pathway |
|
Disease |
H00014 | Non-small cell lung cancer |
|
Gene |
3265 | HRAS; HRas proto-oncogene, GTPase |
3845 | KRAS; KRAS proto-oncogene, GTPase |
4893 | NRAS; NRAS proto-oncogene, GTPase |
11186 | RASSF1; Ras association domain family member 1 |
83593 | RASSF5; Ras association domain family member 5 |
6789 | STK4; serine/threonine kinase 4 |
|
Variant |
|
Reference |
|
Authors |
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS. |
Title |
K-ras mutations in non-small-cell lung carcinoma: a review. |
Journal |
|
Reference |
|
Authors |
Pfeifer GP, Dammann R. |
Title |
Methylation of the tumor suppressor gene RASSF1A in human tumors. |
Journal |
|
LinkDB |
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