| Entry |
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| Name |
Mutation-activated KRAS to RalGDS signaling pathway
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| Definition |
KRAS* -> RALGDS -> RAL |
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| Expanded |
3845v1 -> 5900 -> (5898,5899) |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
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| Gene |
| 3845 | KRAS; KRAS proto-oncogene, GTPase |
| 5900 | RALGDS; ral guanine nucleotide dissociation stimulator |
| 5898 | RALA; RAS like proto-oncogene A |
| 5899 | RALB; RAS like proto-oncogene B |
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| Variant |
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| Reference |
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| Authors |
Karnoub AE, Weinberg RA |
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| Title |
Ras oncogenes: split personalities. |
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| Journal |
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| Reference |
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| Authors |
Janssen KP. |
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| Title |
Murine models of colorectal cancer: studying the role of oncogenic K-ras. |
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| Journal |
|
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| Reference |
|
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| Authors |
Adjei AA. |
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| Title |
Blocking oncogenic Ras signaling for cancer therapy. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. |
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| Title |
Genetics and biology of pancreatic ductal adenocarcinoma. |
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| Journal |
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| LinkDB |
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