Homo sapiens (human): 5900
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Entry
5900 CDS
T01001
Symbol
RALGDS, RGDS, RGF, RalGEF
Name
(RefSeq) ral guanine nucleotide dissociation stimulator
KO
K08732
ral guanine nucleotide dissociation stimulator
Organism
hsa
Homo sapiens (human)
Pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
hsa04072
Phospholipase D signaling pathway
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
hsa05212
Pancreatic cancer
hsa05231
Choline metabolism in cancer
Network
nt06213
Other RAS signaling (cancer)
nt06260
Colorectal cancer
nt06262
Pancreatic cancer
Element
N00103
EGF-EGFR-RAS-RalGDS signaling pathway
N00104
Mutation-activated KRAS to RalGDS signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
5900 (RALGDS)
04015 Rap1 signaling pathway
5900 (RALGDS)
04072 Phospholipase D signaling pathway
5900 (RALGDS)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
5900 (RALGDS)
05231 Choline metabolism in cancer
5900 (RALGDS)
09162 Cancer: specific types
05210 Colorectal cancer
5900 (RALGDS)
05212 Pancreatic cancer
5900 (RALGDS)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RA
Motif
Other DBs
NCBI-GeneID:
5900
NCBI-ProteinID:
NP_006257
OMIM:
601619
HGNC:
9842
Ensembl:
ENSG00000160271
UniProt:
Q12967
Q8N4Y1
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:complement(133097722..133149210)
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AA seq
914 aa
AA seq
DB search
MVQRMWAEAAGPAGGAEPLFPGSRRSRSVWDAVRLEVGVPDSCPVVLHSFTQLDPDLPRP
ESSTQEIGEELINGVIYSISLRKVQLHHGGNKGQRWLGYENESALNLYETCKVRTVKAGT
LEKLVEHLVPAFQGSDLSYVTIFLCTYRAFTTTQQVLDLLFKRYGRCDALTASSRYGCIL
PYSDEDGGPQDQLKNAISSILGTWLDQYSEDFCQPPDFPCLKQLVAYVQLNMPGSDLERR
AHLLLAQLEHSEPIEAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPA
PGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPS
LQPSWPSPVVAENGLSEEKPHLLVFPPDLVAEQFTLMDAELFKKVVPYHCLGSIWSQRDK
KGKEHLAPTIRATVTQFNSVANCVITTCLGNRSTKAPDRARVVEHWIEVARECRILKNFS
SLYAILSALQSNSIHRLKKTWEDVSRDSFRIFQKLSEIFSDENNYSLSRELLIKEGTSKF
ATLEMNPKRAQKRPKETGIIQGTVPYLGTFLTDLVMLDTAMKDYLYGRLINFEKRRKEFE
VIAQIKLLQSACNNYSIAPDEQFGAWFRAVERLSETESYNLSCELEPPSESASNTLRTKK
NTAIVKRWSDRQAPSTELSTSGSSHSKSCDQLRCGPYLSSGDIADALSVHSAGSSSSDVE
EINISFVPESPDGQEKKFWESASQSSPETSGISSASSSTSSSSASTTPVAATRTHKRSVS
GLCNSSSALPLYNQQVGDCCIIRVSLDVDNGNMYKSILVTSQDKAPAVIRKAMDKHNLEE
EEPEDYELLQILSDDRKLKIPENANVFYAMNSTANYDFVLKKRTFTKGVKVKHGASSTLP
RMKQKGLKIAKGIF
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
atggtgcagcgcatgtgggccgaggcggccgggcctgctggcggcgccgagccgctgttt
ccgggctcccggcggagccgcagcgtgtgggacgccgtgcgcctggaggtgggcgtcccc
gacagctgcccggtggtgctgcacagcttcacgcagctagaccccgacctgccgcgcccg
gagagctccacgcaggagatcggtgaggagctgatcaacggagtcatctactccatctcc
ctgcgcaaggtgcagctgcaccacggaggcaacaaggggcagcgctggctcgggtatgag
aatgagtcggccctgaacctttatgagacttgcaaggtgcggaccgtgaaggctggcacg
ctggagaagctggtggagcacctggtgccagccttccagggcagcgacctctcctacgtc
accatcttcctgtgtacctatagagccttcaccaccacccaacaggtcctggacctgctg
ttcaaaaggtacggtagatgtgacgccctcacggcctcctctagatacggctgcatcctc
ccctattccgacgaggatggtggaccccaggaccaacttaaaaatgccatctcctccatc
ctgggcacctggctggaccagtactcggaggatttctgtcaacctccggactttccctgc
ctcaagcagctggtggcctacgtgcagctcaacatgccaggctcagacctggagcgccgt
gcccaccttctcctggcccagctggagcactcggaacccattgaggcagagcctgaggct
ctgtcaccagtgccagctctaaaaccaactccagagctcgagctagctctaacaccagct
cgagcacccagcccagtgccggctccagccccggagccagagccagctccaacaccagct
ccaggttcagagctagaagtagctccagcaccagctccggagctccagcaggctccagag
ccagctgtgggactagaatcggctccagcgccagctctggaactagagccagctccagaa
caggatccagctccctcacaaactctagagctggagccagctccagcaccagttccatca
ttacagccttcctggccttcacctgtggttgcagagaacgggctgagtgaggagaagcct
cacctcttggtgttccctccagatctggtggcagagcagtttacactgatggatgcggaa
ctgttcaagaaggtggtgccctaccactgcctgggctccatctggtcccagcgggacaag
aagggcaaggagcacctggcgcccaccatccgcgccactgtcacccagttcaacagtgtg
gccaactgtgtcatcaccacctgcctcgggaaccgaagcacgaaagccccagacagggcc
agggtggtggagcactggatcgaggtggccagggagtgccggatcctcaagaacttctcg
tcactgtatgccatcctctctgccctgcagagcaactccatccaccgtctgaagaagacg
tgggaagacgtttccagggacagtttccggatctttcagaagctgtcagagatcttctca
gatgagaacaactactcattgagccgggagctgctcatcaaggagggcacctccaagttt
gccaccctggagatgaaccccaagagagcccagaaacggccgaaggagacgggcatcatc
cagggcaccgttccctacctgggcacgttcctcaccgacctggtgatgctggacactgcc
atgaaggactatctgtatggcagactcatcaactttgagaagaggaggaaggagttcgag
gtgatcgcccagatcaagctgctgcagtcggcctgcaacaactacagcatcgcgccagat
gagcaatttggggcctggttccgggccgtggagcggctcagcgagactgagagctacaac
ctgtcgtgcgagctggagcccccatccgagtcagccagcaacaccctcaggaccaagaag
aacacagccattgtcaagcgctggagcgaccgccaggcccccagcactgagctcagtacc
agtggcagctcccactccaagtcctgtgaccagctcaggtgtggcccctacctcagcagc
ggggacatcgctgacgcgctcagcgtgcactcggccggctcctctagctccgacgtggag
gagatcaacatcagcttcgtcccggagtctcctgatggccaggaaaagaagttctgggaa
tcagcctcacagtcatccccggagacctccggcatcagctcagcctccagcagcacctcg
tcctcctcagcctccaccacgcccgtggctgccacacgcacccacaagcgctctgtctca
gggctctgcaactccagctccgcgctgccgctctacaaccagcaggtgggcgactgctgt
atcatccgcgtcagcctggacgtggacaatggcaacatgtacaagagcatcctggtgacc
agccaagataaggctccggctgtaatccgcaaggccatggacaaacacaacctggaggag
gaggagccggaggactatgagctgctgcagattctctcagatgaccggaagctgaagatc
cctgaaaacgccaacgtcttctatgccatgaactctaccgccaactatgactttgtcctc
aagaagcggaccttcaccaagggagtgaaggtcaagcacggagccagctccaccctccct
cgcatgaagcagaaaggactcaagattgccaagggcatcttctga
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