| Entry |
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| Name |
KSHV MIR2 to cell surface molecule-endocytosis
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| Definition |
MIR2 -| (ICAM1,CD86,MICA,MICB,CLEC2B,IFNGR1) |
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| Expanded |
K21666 -| (3383,942,100507436,4277,9976,3459) |
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| Class |
nt06229 MHC presentation (cancer)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
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| Type |
Pathogen
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| Pathway |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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| Disease |
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| Gene |
| 3383 | ICAM1; intercellular adhesion molecule 1 |
| 100507436 | MICA; MHC class I polypeptide-related sequence A |
| 4277 | MICB; MHC class I polypeptide-related sequence B |
| 9976 | CLEC2B; C-type lectin domain family 2 member B |
| 3459 | IFNGR1; interferon gamma receptor 1 |
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| Perturbant |
| K21666 (MIR2) | MIR2; KSHV E3 ubiquitin-protein ligase MIR2 |
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| Reference |
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| Authors |
Ishido S, Choi JK, Lee BS, Wang C, DeMaria M, Johnson RP, Cohen GB, Jung JU |
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| Title |
Inhibition of natural killer cell-mediated cytotoxicity by Kaposi's sarcoma-associated herpesvirus K5 protein. |
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| Journal |
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| Reference |
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| Authors |
Coscoy L, Ganem D |
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| Title |
A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation. |
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| Journal |
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| Reference |
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| Authors |
Liang C, Lee JS, Jung JU |
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| Title |
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis. |
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| Journal |
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| Reference |
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| Authors |
Thomas M, Boname JM, Field S, Nejentsev S, Salio M, Cerundolo V, Wills M, Lehner PJ |
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| Title |
Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity. |
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| Journal |
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| Reference |
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| Authors |
Li Q, Means R, Lang S, Jung JU |
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| Title |
Downregulation of gamma interferon receptor 1 by Kaposi's sarcoma-associated herpesvirus K3 and K5. |
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| Journal |
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| LinkDB |
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