| Entry |
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| Name |
HCV Core to IFN signaling pathway
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| Definition |
Core -| (STAT1+STAT2+IRF9) |
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| Expanded |
K22271 -| (6772+6773+10379) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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|---|
| Disease |
| H00048 | Hepatocellular carcinoma |
|
|---|
| Gene |
| 6772 | STAT1; signal transducer and activator of transcription 1 |
| 6773 | STAT2; signal transducer and activator of transcription 2 |
| 10379 | IRF9; interferon regulatory factor 9 |
|
|---|
| Perturbant |
| K22271 (Core) | Core; HCV core protein |
|
|---|
| Reference |
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| Authors |
Bode JG, Brenndorfer ED, Haussinger D |
|---|
| Title |
Subversion of innate host antiviral strategies by the hepatitis C virus. |
|---|
| Journal |
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| Reference |
|
|---|
| Authors |
Horner SM, Gale M Jr |
|---|
| Title |
Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. |
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| Journal |
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| Reference |
|
|---|
| Authors |
Melen K, Fagerlund R, Nyqvist M, Keskinen P, Julkunen I |
|---|
| Title |
Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs. |
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| Journal |
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| Reference |
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|---|
| Authors |
Lin W, Kim SS, Yeung E, Kamegaya Y, Blackard JT, Kim KA, Holtzman MJ, Chung RT |
|---|
| Title |
Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain. |
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| Journal |
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| LinkDB |
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