KEGG   NETWORK: N00315
Entry
N00315                      Network                                
Name
Mutation-inactivated AIP to AhR-mediated transcription
Definition
AIP* // AHR
  Expanded
9049v1 // 196
Class
nt06360 Cushing syndrome
Type
Variant
Pathway
hsa04934  Cushing syndrome
Disease
H01431  Cushing syndrome
H01102  Pituitary adenomas
Gene
9049  AIP; aryl hydrocarbon receptor interacting protein
196  AHR; aryl hydrocarbon receptor
Variant
9049v1 (AIP*)  AIP mutation
Reference
  Authors
Jaffrain-Rea ML, Angelini M, Gargano D, Tichomirowa MA, Daly AF, Vanbellinghen JF, D'Innocenzo E, Barlier A, Giangaspero F, Esposito V, Ventura L, Arcella A, Theodoropoulou M, Naves LA, Fajardo C, Zacharieva S, Rohmer V, Brue T, Gulino A, Cantore G, Alesse E, Beckers A
  Title
Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.
  Journal
Endocr Relat Cancer 16:1029-43 (2009)
DOI:10.1677/ERC-09-0094
Reference
  Authors
Dworakowska D, Korbonits M, Aylwin S, McGregor A, Grossman AB
  Title
The pathology of pituitary adenomas from a clinical perspective.
  Journal
Front Biosci (Schol Ed) 3:105-16 (2011)
DOI:10.2741/136
Reference
  Authors
Lecoq AL, Kamenicky P, Guiochon-Mantel A, Chanson P
  Title
Genetic mutations in sporadic pituitary adenomas--what to screen for?
  Journal
Nat Rev Endocrinol 11:43-54 (2015)
DOI:10.1038/nrendo.2014.181
Reference
  Authors
Ozfirat Z, Korbonits M
  Title
AIP gene and familial isolated pituitary adenomas.
  Journal
Mol Cell Endocrinol 326:71-9 (2010)
DOI:10.1016/j.mce.2010.05.001
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