KEGG   NETWORK: N00350
Entry
N00350                      Network                                
Name
HPV E6 to extrinsic apoptotic pathway
Definition
E6 -| TNFRSF1A
  Expanded
K21807 -| 7132
Class
nt06166 Human papillomavirus (HPV)
Type
Pathogen
Pathway
hsa05165  Human papillomavirus infection
hsa04061  Viral protein interaction with cytokine and cytokine receptor
Disease
H00030  Cervical cancer
Gene
7132  TNFRSF1A; TNF receptor superfamily member 1A
Perturbant
K21807 (E6)  E6; HPV protein E6
Reference
  Authors
Jayshree RS, Sreenivas A, Tessy M, Krishna S
  Title
Cell intrinsic & extrinsic factors in cervical carcinogenesis.
  Journal
Indian J Med Res 130:286-95 (2009)
Reference
  Authors
Garnett TO, Duerksen-Hughes PJ
  Title
Modulation of apoptosis by human papillomavirus (HPV) oncoproteins.
  Journal
Arch Virol 151:2321-35 (2006)
DOI:10.1007/s00705-006-0821-0
Reference
  Authors
Filippova M, Song H, Connolly JL, Dermody TS, Duerksen-Hughes PJ
  Title
The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis.
  Journal
J Biol Chem 277:21730-9 (2002)
DOI:10.1074/jbc.M200113200
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