Entry |
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Name |
EBV BPLF1 to TLR2/4-NFKB signaling pathway
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Definition |
BPLF1 -| (TRAF6+TAK1+(TAB1,TAB2)) |
Expanded |
K22972 -| (7189+6885+(10454,23118)) |
Class |
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Type |
Pathogen
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Pathway |
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Disease |
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Gene |
7189 | TRAF6; TNF receptor associated factor 6 |
6885 | MAP3K7; mitogen-activated protein kinase kinase kinase 7 |
10454 | TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1 |
23118 | TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
|
Perturbant |
K22972 (BPLF1) | BPLF1; EBV large tegment protein deneddylase |
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Reference |
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Authors |
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME |
Title |
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling. |
Journal |
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Reference |
|
Authors |
Rajsbaum R, Garcia-Sastre A |
Title |
Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways. |
Journal |
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Reference |
|
Authors |
Saito S, Murata T, Kanda T, Isomura H, Narita Y, Sugimoto A, Kawashima D, Tsurumi T |
Title |
Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-kappaB signaling during productive replication. |
Journal |
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LinkDB |
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