| Entry |
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| Name |
EBV BPLF1 to TLR2/4-NFKB signaling pathway
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| Definition |
BPLF1 -| (TRAF6+TAK1+(TAB1,TAB2)) |
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| Expanded |
K22972 -| (7189+6885+(10454,23118)) |
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| Class |
nt06121 TLR signaling (viruses and bacteria)
nt06165 Epstein-Barr virus (EBV)
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 7189 | TRAF6; TNF receptor associated factor 6 |
| 6885 | MAP3K7; mitogen-activated protein kinase kinase kinase 7 |
| 10454 | TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1 |
| 23118 | TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
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| Perturbant |
| K22972 (BPLF1) | BPLF1; EBV large tegment protein deneddylase |
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| Reference |
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| Authors |
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME |
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| Title |
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling. |
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| Journal |
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| Reference |
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| Authors |
Rajsbaum R, Garcia-Sastre A |
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| Title |
Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways. |
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| Journal |
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| Reference |
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| Authors |
Saito S, Murata T, Kanda T, Isomura H, Narita Y, Sugimoto A, Kawashima D, Tsurumi T |
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| Title |
Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-kappaB signaling during productive replication. |
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| Journal |
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| LinkDB |
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