| Entry |
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| Gene name |
TAB1, 3'-Tab1, MAP3K7IP1
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| Definition |
(RefSeq) TGF-beta activated kinase 1 (MAP3K7) binding protein 1
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| KO |
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| Organism |
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| Pathway |
| hsa04620 | Toll-like receptor signaling pathway |
| hsa04621 | NOD-like receptor signaling pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
| hsa05168 | Herpes simplex virus 1 infection |
| hsa05170 | Human immunodeficiency virus 1 infection |
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| Network |
nt06110 MAPK signaling (viruses and bacteria) nt06121 TLR signaling (viruses and bacteria) nt06123 TNF signaling (viruses and bacteria) nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06161 Human immunodeficiency virus type 1 (HIV-1) nt06163 Hepatitis C virus (HCV) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06165 Epstein-Barr virus (EBV) nt06167 Human cytomegalovirus (HCMV) nt06211 Other MAPK signaling nt06223 TNF signaling nt06263 Hepatocellular carcinoma nt06416 TNF signaling nt06461 Huntington disease |
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| Element |
| N00151 | TNF-NFKB signaling pathway |
| N00186 | IL1-IL1R-p38 signaling pathway |
| N00188 | IL1-IL1R-JNK signaling pathway |
| N00265 | EBV LMP1 to NFKB signaling pathway |
| N00441 | HIV gp120 to TNF-NFKB signaling pathway |
| N00442 | HIV Nef to TNF-NFKB signaling pathway |
| N00444 | TNF-p38 signaling pathway |
| N00446 | TNF-JNK signaling pathway |
| N00466 | EBV BPLF1 to TLR2/4-NFKB signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
10454 (TAB1)
04064 NF-kappa B signaling pathway
10454 (TAB1)
04668 TNF signaling pathway
10454 (TAB1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
10454 (TAB1)
04621 NOD-like receptor signaling pathway
10454 (TAB1)
09158 Development and regeneration
04380 Osteoclast differentiation
10454 (TAB1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
10454 (TAB1)
05161 Hepatitis B
10454 (TAB1)
05168 Herpes simplex virus 1 infection
10454 (TAB1)
05169 Epstein-Barr virus infection
10454 (TAB1)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
10454 (TAB1)
05132 Salmonella infection
10454 (TAB1)
05131 Shigellosis
10454 (TAB1)
05135 Yersinia infection
10454 (TAB1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
10454 (TAB1)
05140 Leishmaniasis
10454 (TAB1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
10454 (TAB1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Structure |
PDB: |
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| Position |
22q13.1
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| AA seq |
504 aa
MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN
NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES
IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV
ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST
RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH
GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL
LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG
AHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEP
YVDFAEFYRLWSVDHGEQSVVTAP |
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| NT seq |
1515 nt +upstreamnt +downstreamnt
atggcggcgcagaggaggagcttgctgcagagtgagcagcagccaagctggacagatgac
ctgcctctctgccacctctctggggttggctcagcctccaaccgcagctactctgctgat
ggcaagggcactgagagccacccgccagaggacagctggctcaagttcaggagtgagaac
aactgcttcctgtatggggtcttcaacggctatgatggcaaccgagtgaccaacttcgtg
gcccagcggctgtccgcagagctcctgctgggccagctgaatgccgagcacgccgaggcc
gatgtgcggcgtgtgctgctgcaggccttcgatgtggtggagaggagcttcctggagtcc
attgacgacgccttggctgagaaggcaagcctccagtcgcaattgccagagggagtccct
cagcaccagctgcctcctcagtatcagaagatccttgagagactcaagacgttagagagg
gaaatttcgggaggggccatggccgttgtggcggtccttctcaacaacaagctctacgtc
gccaatgtcggtacaaaccgtgcacttttatgcaaatcgacagtggatgggttgcaggtg
acacagctgaacgtggaccacaccacagagaacgaggatgagctcttccgtctttcgcag
ctgggcttggatgctggaaagatcaagcaggtggggatcatctgtgggcaggagagcacc
cggcggatcggggattacaaggttaaatatggctacacggacattgaccttctcagcgct
gccaagtccaaaccaatcatcgcagagccagaaatccatggggcacagccgctggatggg
gtgacgggcttcttggtgctgatgtcggaggggttgtacaaggccctagaggcagcccat
gggcctgggcaggccaaccaggagattgctgcgatgattgacactgagtttgccaagcag
acctccctggacgcagtggcccaggccgtcgtggaccgggtgaagcgcatccacagcgac
accttcgccagtggtggggagcgtgccaggttctgcccccggcacgaggacatgaccctg
ctagtgaggaactttggctacccgctgggcgaaatgagccagcccacaccgagcccagcc
ccagctgcaggaggacgagtgtaccctgtgtctgtgccatactccagcgcccagagcacc
agcaagaccagcgtgaccctctcccttgtcatgccctcccagggccagatggtcaacggg
gctcacagtgcttccaccctggacgaagccacccccaccctcaccaaccaaagcccgacc
ttaaccctgcagtccaccaacacgcacacgcagagcagcagctccagctctgacggaggc
ctcttccgctcccggcccgcccactcgctcccgcctggcgaggacggtcgtgttgagccc
tatgtggactttgctgagttttaccgcctctggagcgtggaccatggcgagcagagcgtg
gtgacagcaccgtag |
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