Entry |
|
Name |
EBV EBNA3C to p27-Cell cycle G1/S
|
Definition |
EBNA3C -> ((CCNA,CCNE)+CDK2) -> RB1 // E2F |
Expanded |
K19458 -> ((890,8900,898,9134)+1017) -> 5925 // (1869,1870,1871) |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
|
Gene |
1017 | CDK2; cyclin dependent kinase 2 |
5925 | RB1; RB transcriptional corepressor 1 |
1869 | E2F1; E2F transcription factor 1 |
1870 | E2F2; E2F transcription factor 2 |
1871 | E2F3; E2F transcription factor 3 |
|
Perturbant |
K19458 (EBNA3C) | EBNA6; EBV nuclear antigen 6 |
|
Reference |
|
Authors |
Kumar P, Murakami M, Kaul R, Saha A, Cai Q, Robertson ES |
Title |
Deregulation of the cell cycle machinery by Epstein-Barr virus nuclear antigen 3C. |
Journal |
|
Reference |
|
Authors |
Saha A, Robertson ES |
Title |
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes. |
Journal |
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LinkDB |
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