KEGG   NETWORK: N00517
Entry
N00517                      Network                                

Name
HCV NS3/4A to TLR3-IRF3 signaling pathway
Definition
(NS3,NS4A) -| IRF3
  Expanded
(K22273,K22274) -| 3661
Class
nt06121 TLR signaling (viruses and bacteria)
nt06163 Hepatitis C virus (HCV)
Type
Pathogen
Pathway
hsa05160  Hepatitis C
Disease
H00048  Hepatocellular carcinoma
Gene
3661  IRF3; interferon regulatory factor 3
Perturbant
K22273 (NS3)  NS3; HCV serine protease NS3
K22274 (NS4A)  NS4A; HCV non-structural protein 4A
Reference
  Authors
Asselah T, Bieche I, Sabbagh A, Bedossa P, Moreau R, Valla D, Vidaud M, Marcellin P
  Title
Gene expression and hepatitis C virus infection.
  Journal
Gut 58:846-58 (2009)
DOI:10.1136/gut.2008.166348
Reference
  Authors
Gale M Jr, Foy EM
  Title
Evasion of intracellular host defence by hepatitis C virus.
  Journal
Nature 436:939-45 (2005)
DOI:10.1038/nature04078
LinkDB

DBGET integrated database retrieval system