| Entry |
|
|---|
| Name |
|
|---|
| Definition |
CDKN2A -| MDM2 -| TP53 => CDKN1A -| (CCNE+CDK2) -> RB1 // E2F |
|---|
| Expanded |
1029 -| 4193 -| 7157 => 1026 -| ((898,9134)+1017) -> 5925 // (1869,1870,1871) |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
|
|---|
| Gene |
| 1029 | CDKN2A; cyclin dependent kinase inhibitor 2A |
| 4193 | MDM2; MDM2 proto-oncogene |
| 7157 | TP53; tumor protein p53 |
| 1026 | CDKN1A; cyclin dependent kinase inhibitor 1A |
| 1017 | CDK2; cyclin dependent kinase 2 |
| 5925 | RB1; RB transcriptional corepressor 1 |
| 1869 | E2F1; E2F transcription factor 1 |
| 1870 | E2F2; E2F transcription factor 2 |
| 1871 | E2F3; E2F transcription factor 3 |
|
|---|
| Reference |
|
|---|
| Authors |
Sheppard KE, McArthur GA |
|---|
| Title |
The cell-cycle regulator CDK4: an emerging therapeutic target in melanoma. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Subramanian M, Jones MF, Lal A |
|---|
| Title |
Long Non-Coding RNAs Embedded in the Rb and p53 Pathways. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Otto T, Sicinski P |
|---|
| Title |
Cell cycle proteins as promising targets in cancer therapy. |
|---|
| Journal |
|
|---|
| LinkDB |
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