| Entry |
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| Name |
LHCGR-GNAS-PKA signaling pathway
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| Definition |
(LHB+CGA) -> LHCGR -> GNAS -> ADCY -> cAMP -> PKA |
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| Expanded |
(3972+1081) -> 3973 -> 2778 -> (107,108,109,196883,111,112,113,114,115) -> C00575 -> (5566+5567+5568) |
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| Class |
nt06323 KISS1-GnRH-LH/FSH-E2 signaling
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| Type |
Reference
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| Pathway |
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| Gene |
| 3972 | LHB; luteinizing hormone beta polypeptide |
| 1081 | CGA; glycoprotein hormones, alpha polypeptide |
| 3973 | LHCGR; luteinizing hormone/choriogonadotropin receptor |
| 2778 | GNAS; GNAS complex locus |
| 107 | ADCY1; adenylate cyclase 1 |
| 108 | ADCY2; adenylate cyclase 2 |
| 109 | ADCY3; adenylate cyclase 3 |
| 196883 | ADCY4; adenylate cyclase 4 |
| 111 | ADCY5; adenylate cyclase 5 |
| 112 | ADCY6; adenylate cyclase 6 |
| 113 | ADCY7; adenylate cyclase 7 |
| 114 | ADCY8; adenylate cyclase 8 |
| 115 | ADCY9; adenylate cyclase 9 |
| 5566 | PRKACA; protein kinase cAMP-activated catalytic subunit alpha |
| 5567 | PRKACB; protein kinase cAMP-activated catalytic subunit beta |
| 5568 | PRKACG; protein kinase cAMP-activated catalytic subunit gamma |
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| Metabolite |
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| Reference |
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| Authors |
Choi J, Smitz J |
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| Title |
Luteinizing hormone and human chorionic gonadotropin: origins of difference. |
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| Journal |
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| Reference |
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| Authors |
Bjelic MM, Stojkov NJ, Baburski AZ, Sokanovic SJ, Mihajlovic AI, Janjic MM, Kostic TS, Andric SA |
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| Title |
Molecular adaptations of testosterone-producing Leydig cells during systemic in vivo blockade of the androgen receptor. |
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| Journal |
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| LinkDB |
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