NETWORK: N00930
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Entry
N00930 Network
Name
Escherichia NleD to TNF-JNK signaling pathway
Definition
NleD -| JNK
Expanded
K23656 -| (5599,
5601,
5602)
Class
nt06516
TNF signaling
Type
Pathogen
Pathway
hsa05130
Pathogenic Escherichia coli infection
Disease
H00277
Enterohemorrhagic Escherichia coli (EHEC) infection
H00278
Enteropathogenic Escherichia coli (EPEC) infection
Gene
5599
MAPK8; mitogen-activated protein kinase 8
5601
MAPK9; mitogen-activated protein kinase 9
5602
MAPK10; mitogen-activated protein kinase 10
Perturbant
K23656
(NleD)
nleD; T3SS secreted effector NleD
Reference
PMID:
21113130
Authors
Baruch K, Gur-Arie L, Nadler C, Koby S, Yerushalmi G, Ben-Neriah Y, Yogev O, Shaulian E, Guttman C, Zarivach R, Rosenshine I
Title
Metalloprotease type III effectors that specifically cleave JNK and NF-kappaB.
Journal
EMBO J 30:221-31 (2011)
DOI:
10.1038/emboj.2010.297
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