| Entry |
|
|---|
| Name |
Mutation-caused aberrant Htt to REST-mediated transcriptional repression
|
|---|
| Definition |
HTT* // REST == (SIN3A+RCOR1+(HDAC1,HDAC2)) =| BDNF |
|---|
| Expanded |
3064v1 // 5978 == (25942+23186+(3065,3066)) =| 627 |
|---|
| Class |
|
|---|
| Type |
Variant
|
|---|
| Pathway |
|
|---|
| Disease |
|
|---|
| Gene |
| 5978 | REST; RE1 silencing transcription factor |
| 25942 | SIN3A; SIN3 transcription regulator family member A |
| 23186 | RCOR1; REST corepressor 1 |
| 3065 | HDAC1; histone deacetylase 1 |
| 3066 | HDAC2; histone deacetylase 2 |
| 627 | BDNF; brain derived neurotrophic factor |
|
|---|
| Variant |
|
|---|
| Reference |
|
|---|
| Authors |
Landles C, Bates GP |
|---|
| Title |
Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Cattaneo E, Zuccato C, Tartari M |
|---|
| Title |
Normal huntingtin function: an alternative approach to Huntington's disease. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Moumne L, Betuing S, Caboche J |
|---|
| Title |
Multiple Aspects of Gene Dysregulation in Huntington's Disease. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
