Homo sapiens (human): 627
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Entry
627 CDS
T01001
Symbol
BDNF, ANON2, BULN2
Name
(RefSeq) brain derived neurotrophic factor
KO
K04355
brain-derived neurotrophic factor
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04014
Ras signaling pathway
hsa04024
cAMP signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04722
Neurotrophin signaling pathway
hsa05016
Huntington disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05030
Cocaine addiction
hsa05034
Alcoholism
Network
nt06461
Huntington disease
nt06526
MAPK signaling
nt06530
PI3K signaling
Element
N00980
Mutation-caused aberrant Htt to REST-mediated transcriptional repression
N01592
GF-RTK-RAS-ERK signaling pathway
N01656
GF-RTK-PI3K signaling pathway
N01658
GF-RTK-RAS-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
627 (BDNF)
04024 cAMP signaling pathway
627 (BDNF)
04151 PI3K-Akt signaling pathway
627 (BDNF)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
627 (BDNF)
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
627 (BDNF)
05022 Pathways of neurodegeneration - multiple diseases
627 (BDNF)
09165 Substance dependence
05030 Cocaine addiction
627 (BDNF)
05034 Alcoholism
627 (BDNF)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
627 (BDNF)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Growth factors (RTK binding)
627 (BDNF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NGF
NTF3_N
Spaetzle
Motif
Other DBs
NCBI-GeneID:
627
NCBI-ProteinID:
NP_001137277
OMIM:
113505
HGNC:
1033
Ensembl:
ENSG00000176697
UniProt:
P23560
A0A0E3SU01
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(27654893..27722030)
Genome browser
AA seq
247 aa
AA seq
DB search
MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLA
DTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAA
NMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQY
FYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCT
LTIKRGR
NT seq
744 nt
NT seq
+upstream
nt +downstream
nt
atgaccatccttttccttactatggttatttcatactttggttgcatgaaggctgccccc
atgaaagaagcaaacatccgaggacaaggtggcttggcctacccaggtgtgcggacccat
gggactctggagagcgtgaatgggcccaaggcaggttcaagaggcttgacatcattggct
gacactttcgaacacgtgatagaagagctgttggatgaggaccagaaagttcggcccaat
gaagaaaacaataaggacgcagacttgtacacgtccagggtgatgctcagtagtcaagtg
cctttggagcctcctcttctctttctgctggaggaatacaaaaattacctagatgctgca
aacatgtccatgagggtccggcgccactctgaccctgcccgccgaggggagctgagcgtg
tgtgacagtattagtgagtgggtaacggcggcagacaaaaagactgcagtggacatgtcg
ggcgggacggtcacagtccttgaaaaggtccctgtatcaaaaggccaactgaagcaatac
ttctacgagaccaagtgcaatcccatgggttacacaaaagaaggctgcaggggcatagac
aaaaggcattggaactcccagtgccgaactacccagtcgtacgtgcgggcccttaccatg
gatagcaaaaagagaattggctggcgattcataaggatagacacttcttgtgtatgtaca
ttgaccattaaaaggggaagatag
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