| Entry |
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| Name |
FAS-JNK signaling pathway
|
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| Definition |
FASLG -> FAS -> (DAXX+ASK1) -> JNK |
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| Expanded |
356 -> 355 -> (1616+4217) -> (5599,5601,5602) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 355 | FAS; Fas cell surface death receptor |
| 1616 | DAXX; death domain associated protein |
| 4217 | MAP3K5; mitogen-activated protein kinase kinase kinase 5 |
| 5599 | MAPK8; mitogen-activated protein kinase 8 |
| 5601 | MAPK9; mitogen-activated protein kinase 9 |
| 5602 | MAPK10; mitogen-activated protein kinase 10 |
|
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| Reference |
|
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| Authors |
Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D |
|---|
| Title |
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Yang X, Khosravi-Far R, Chang HY, Baltimore D |
|---|
| Title |
Daxx, a novel Fas-binding protein that activates JNK and apoptosis. |
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| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Leist M, Jaattela M |
|---|
| Title |
Four deaths and a funeral: from caspases to alternative mechanisms. |
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| Journal |
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| LinkDB |
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