KEGG   NETWORK: N01121
Entry
N01121                      Network                                
Name
Salmonella SpvC to ERK signaling pathway
Definition
SpvC -| ERK
  Expanded
K13450 -| (5594,5595)
Class
nt06181 Salmonella
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
5594  MAPK1; mitogen-activated protein kinase 1
5595  MAPK3; mitogen-activated protein kinase 3
Perturbant
K13450 (SpvC)  ospF; phosphothreonine lyase
Reference
  Authors
Haneda T, Ishii Y, Shimizu H, Ohshima K, Iida N, Danbara H, Okada N
  Title
Salmonella type III effector SpvC, a phosphothreonine lyase, contributes to reduction in inflammatory response during intestinal phase of infection.
  Journal
Cell Microbiol 14:485-99 (2012)
DOI:10.1111/j.1462-5822.2011.01733.x
Reference
  Authors
Mazurkiewicz P, Thomas J, Thompson JA, Liu M, Arbibe L, Sansonetti P, Holden DW
  Title
SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases.
  Journal
Mol Microbiol 67:1371-83 (2008)
DOI:10.1111/j.1365-2958.2008.06134.x
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