KEGG   NETWORK: N01131
Entry
N01131                      Network                                
Name
Salmonella SopE/E2 to RhoA signaling pathway
Definition
SopE/E2 -> RHOA -> ROCK2 -> FHOD1
  Expanded
K13741 -> 387 -> 9475 -> 29109
Class
nt06135 Cytoskeletal regulation (viruses and bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
387  RHOA; ras homolog family member A
9475  ROCK2; Rho associated coiled-coil containing protein kinase 2
29109  FHOD1; formin homology 2 domain containing 1
Perturbant
K13741 (SopE/E2)  sopE; guanine nucleotide exchange factor SopE
Reference
  Authors
Truong D, Brabant D, Bashkurov M, Wan LC, Braun V, Heo WD, Meyer T, Pelletier L, Copeland J, Brumell JH
  Title
Formin-mediated actin polymerization promotes Salmonella invasion.
  Journal
Cell Microbiol 15:2051-63 (2013)
DOI:10.1111/cmi.12173
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