KEGG   NETWORK: N01290
Entry
N01290                      Network                                

Name
Escherichia NleA to COPII vesicle formation
Definition
NleA -| SEC24
  Expanded
K16041 -| (10802,10427,9632,9871)
Class
nt06125 Membrane trafficking (bacteria)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
10802  SEC24A; SEC24 homolog A, COPII coat complex component
10427  SEC24B; SEC24 homolog B, COPII coat complex component
9632  SEC24C; SEC24 homolog C, COPII coat complex component
9871  SEC24D; SEC24 homolog D, COPII coat complex component
Perturbant
K16041 (NleA)  nleA; non-LEE-encoded effector NleA
Reference
  Authors
Thanabalasuriar A, Bergeron J, Gillingham A, Mimee M, Thomassin JL, Strynadka N, Kim J, Gruenheid S
  Title
Sec24 interaction is essential for localization and virulence-associated function of the bacterial effector protein NleA.
  Journal
Cell Microbiol 14:1206-18 (2012)
DOI:10.1111/j.1462-5822.2012.01789.x
Reference
  Authors
Reddick LE, Alto NM
  Title
Bacteria fighting back: how pathogens target and subvert the host innate immune system.
  Journal
Mol Cell 54:321-8 (2014)
DOI:10.1016/j.molcel.2014.03.010
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