Entry |
|
Name |
Escherichia EspG to RAB1 signaling pathway
|
Definition |
(EspG,EspG2) -| RAB1 |
Expanded |
(K12785,K12809) -| (5861,81876) |
Class |
nt06125 Membrane trafficking (bacteria)
|
Type |
Pathogen
|
Pathway |
hsa05130 | Pathogenic Escherichia coli infection |
|
Disease |
H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
|
Gene |
5861 | RAB1A; RAB1A, member RAS oncogene family |
81876 | RAB1B; RAB1B, member RAS oncogene family |
|
Perturbant |
K12785 (EspG) | espG; LEE-encoded effector EspG |
K12809 (EspG2) | espG2; T3SS secreted effector EspG-like protein |
|
Reference |
|
Authors |
Dong N, Zhu Y, Lu Q, Hu L, Zheng Y, Shao F |
Title |
Structurally distinct bacterial TBC-like GAPs link Arf GTPase to Rab1 inactivation to counteract host defenses. |
Journal |
|
Reference |
|
Authors |
Reddick LE, Alto NM |
Title |
Bacteria fighting back: how pathogens target and subvert the host innate immune system. |
Journal |
|
LinkDB |
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