KEGG   ORTHOLOGY: K12785
Entry
K12785                      KO                                     
Symbol
espG, virA
Name
LEE-encoded effector EspG
Pathway
map05100  Bacterial invasion of epithelial cells
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
Module
M00542  EHEC/EPEC pathogenicity signature, T3SS and effectors
Network
nt06180  Pathogenic Escherichia coli
  Element
N01084  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01085  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01292  Escherichia EspG to RAB1 signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K12785  espG, virA; LEE-encoded effector EspG
   05131 Shigellosis
    K12785  espG, virA; LEE-encoded effector EspG
   05100 Bacterial invasion of epithelial cells
    K12785  espG, virA; LEE-encoded effector EspG
Genes
ECE: Z5142
ECS: ECs_4590(espG)
ECF: ECH74115_5081
ETW: ECSP_4704(espG)
ELX: CDCO157_4324
EOI: ECO111_3731(espG)
EOJ: ECO26_5250(espG)
EOH: ECO103_3639(espG)
ECOO: ECRM13514_4721(espG)
ECOH: ECRM13516_4503(espG)
ECG: E2348C_3970(espG)
EOK: G2583_4444(espG)
SFL: CP0181(virA)
SFE: SFxv_5026(virA)
SSN: SSON_P142(virA)
SDY: SDY_P211(virA)
CRO: ROD_29681(espG)
 » show all
Reference
  Authors
Matsuzawa T, Kuwae A, Yoshida S, Sasakawa C, Abe A.
  Title
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1.
  Journal
EMBO J 23:3570-82 (2004)
DOI:10.1038/sj.emboj.7600359
Reference
  Authors
Yoshida S, Handa Y, Suzuki T, Ogawa M, Suzuki M, Tamai A, Abe A, Katayama E, Sasakawa C
  Title
Microtubule-severing activity of Shigella is pivotal for intercellular spreading.
  Journal
Science 314:985-9 (2006)
DOI:10.1126/science.1133174
  Sequence
[sfl:CP0181]
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