 | | NETWORK: N01321 | |
| Entry |
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| Name |
SARS-CoV-2 nsp1/6/13, ORF3a/6/7b and M to IFN signaling pathway
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| Definition |
(nsp1,nsp6,nsp13,ORF3a,ORF6,ORF7b,M) -| STAT1 |
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| Expanded |
(K25011,K25016,K25022,K24579,K24580,K24582,K24150) -| 6772 |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 6772 | STAT1; signal transducer and activator of transcription 1 |
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| Perturbant |
| K25011 (nsp1) | nsp1; SARS coronavirus host translation inhibitor nsp1 |
| K25016 (nsp6) | nsp6; SARS coronavirus non-structural protein 6 |
| K25022 (nsp13) | nsp13; SARS coronavirus helicase |
| K24579 (ORF3a) | 3a; SARS coronavirus accessory protein 3a |
| K24580 (ORF6) | 6; SARS coronavirus accessory protein 6 |
| K24582 (ORF7b) | 7b; SARS coronavirus accessory protein 7b |
| K24150 (M) | M; SARS coronavirus membrane protein |
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| Reference |
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| Authors |
Xia H, Cao Z, Xie X, Zhang X, Chen JY, Wang H, Menachery VD, Rajsbaum R, Shi PY |
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| Title |
Evasion of Type I Interferon by SARS-CoV-2. |
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| Journal |
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| Reference |
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| Authors |
Harrison AG, Lin T, Wang P |
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| Title |
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis. |
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| Journal |
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| Reference |
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| Authors |
Yuen CK, Lam JY, Wong WM, Mak LF, Wang X, Chu H, Cai JP, Jin DY, To KK, Chan JF, Yuen KY, Kok KH |
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| Title |
SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. |
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| Journal |
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| Reference |
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| Authors |
Lei X, Dong X, Ma R, Wang W, Xiao X, Tian Z, Wang C, Wang Y, Li L, Ren L, Guo F, Zhao Z, Zhou Z, Xiang Z, Wang J |
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| Title |
Activation and evasion of type I interferon responses by SARS-CoV-2. |
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| Journal |
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| LinkDB |
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