NETWORK: N01453
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Entry
N01453 Network
Name
BMP signaling pathway
Definition
BMP -> ((ACVR2A,
ACVR2B,
BMPR2)+(BMPR1A,
BMPR1B,
ACVR1)) -> (SMAD1,
SMAD5,
SMAD9) == SMAD4
Expanded
(650,
652,
653,
654,
655,
353500,
656,
8200,
392255,
151449) -> ((92,
93,
659)+(657,
658,
90)) -> (4086,
4090,
4093) == 4089
Class
nt06507
TGFB signaling
Type
Reference
Pathway
hsa04350
TGF-beta signaling pathway
Gene
650
BMP2; bone morphogenetic protein 2
652
BMP4; bone morphogenetic protein 4
653
BMP5; bone morphogenetic protein 5
654
BMP6; bone morphogenetic protein 6
655
BMP7; bone morphogenetic protein 7
353500
BMP8A; bone morphogenetic protein 8a
656
BMP8B; bone morphogenetic protein 8b
8200
GDF5; growth differentiation factor 5
392255
GDF6; growth differentiation factor 6
151449
GDF7; growth differentiation factor 7
92
ACVR2A; activin A receptor type 2A
93
ACVR2B; activin A receptor type 2B
659
BMPR2; bone morphogenetic protein receptor type 2
657
BMPR1A; bone morphogenetic protein receptor type 1A
658
BMPR1B; bone morphogenetic protein receptor type 1B
90
ACVR1; activin A receptor type 1
4086
SMAD1; SMAD family member 1
4090
SMAD5; SMAD family member 5
4093
SMAD9; SMAD family member 9
4089
SMAD4; SMAD family member 4
Reference
PMID:
26115564
Authors
Seeger P, Musso T, Sozzani S
Title
The TGF-beta superfamily in dendritic cell biology.
Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:
10.1016/j.cytogfr.2015.06.002
Reference
PMID:
23612460
Authors
Wakefield LM, Hill CS
Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:
10.1038/nrc3500
Reference
PMID:
27252362
Authors
Katagiri T, Watabe T
Title
Bone Morphogenetic Proteins.
Journal
Cold Spring Harb Perspect Biol 8:a021899 (2016)
DOI:
10.1101/cshperspect.a021899
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